Search
Search Results
-
MiR-217 regulates autophagy through OPG/RANKL/RANK in giant cell tumors
BackgroundIncreasing evidence suggests that microRNAs (miRNAs) play a crucial role in cancer development and progression. Our previous study showed...
-
LncRNA-NEAT1 blocks the Wnt/β-catenin signaling pathway by targeting miR-217 to inhibit trophoblast cell migration and invasion
ObjectiveThis study aimed to study the correlation between preeclampsia (PE) and lncRNA nuclear paraspeckle assembly transcript 1 (NEAT1), and to...
-
Epigenetic modification of miR-217 promotes intervertebral disc degeneration by targeting the FBXO21-ERK signalling pathway
BackgroundNumerous potential therapeutic alternatives for intervertebral disc degeneration (IDD) have been investigated, the most promising of which...
-
Circular RNA hsa_circ_0023404 promotes the proliferation, migration and invasion in endometrial cancer cells through regulating miR-217/MAPK1 axis
BackgroundEmerging studies indicated that circular RNA hsa_circ_ 0023404 and its target miR-217/MARK1 axis play a critical role in cancer progression...
-
Serum MicroRNA profiles in chronic hepatitis C Egyptian patients before and after combined sofosbuvir and daclatasvir treatment
BackgroundMicroRNAs (miR) are small sequence of nucleotides that can affect multiple genes involved in the hepatitis C virus (HCV) life cycle and...
-
Metabolic memory in diabetic foot syndrome (DFS): MICRO-RNAS, single nucleotide polymorphisms (SNPs) frequency and their relationship with indices of endothelial function and adipo-inflammatory dysfunction
BackgroundDiabetic foot is a significant cause of morbidity in diabetic patients, with a rate that is approximately twice that of patients without...
-
Expression of miR-217 and HIF-1α/VEGF pathway in patients with diabetic foot ulcer and its effect on angiogenesis of diabetic foot ulcer rats
ObjectiveTo investigate the expression of miR-217 and HIF-1α/VEGF pathway in patients with diabetic foot ulcer (DFU) and its effect on angiogenesis...
-
MicroRNA-135 inhibits initiation of epithelial-mesenchymal transition in breast cancer by targeting ZNF217 and promoting m6A modification of NANOG
MicroRNAs play significant roles in various malignancies, with breast cancer (BC) being no exception. Consequently, we explored the functional...
-
CircRNA-100284 activates aurora kinase B by inducing methylation of HSP70 via microRNA-217 to promote proliferation of bladder cancer cells
ObjectiveThe malignant transformation of normal bladder cells (SV-HUC-1) was induced by arsenite to explore the possible mechanism of circRNA-100284...
-
Estrogen receptor β promotes renal cell carcinoma progression via regulating LncRNA HOTAIR-miR-138/200c/204/217 associated CeRNA network
Recent studies indicated that the estrogen receptor beta (ERβ) could affect the progression of prostate and bladder tumors, however, its roles in the...
-
Disregulation of miR-216a and miR-217 in Gastric Cancer and Their Clinical Significance
ObjectiveThe majority of gastric cancer (GC) diagnoses occur at the middle or late stage of the disease, indicating that finding novel biomarkers...
-
Diagnostic and prognostic significance of miR-320a-3p in patients with chronic heart failure
AimThe purpose of this study was to investigate the diagnostic and prognostic value of miR-320a-3p in chronic heart failure (CHF).
Methods ...
-
Moderate evidence exists for four microRNAs as potential biomarkers for tendinopathies and degenerative tendon ruptures at the upper extremity in elderly patients: conclusion of a systematic review with best-evidence synthesis
PurposeThe aim of this systematic review was to investigate tendon-specific microRNAs (miRNAs) as biomarkers for the detection of tendinopathies or...
-
The role of microRNAs in brain metastasis
Brain metastasis (BM) is the most common type of brain tumor and frequently foreshadows disease progression and poor overall survival with patients...
-
Unraveling the miRNA Puzzle in Atherosclerosis: Revolutionizing Diagnosis, Prognosis, and Therapeutic Approaches
Purpose of ReviewTo eradicate atherosclerotic diseases, novel biomarkers, and future therapy targets must reveal the burden of early atherosclerosis...
-
Surgical suction filter-derived bone graft displays osteogenic miRNA and mRNA patterns
PurposeRecently, a surgical suction filter device was introduced which aims at generating a suction filter-derived bone grafting substitute (SF-BGS)....
-
The roles of lncRNAs in Th17-associated diseases, with special focus on JAK/STAT signaling pathway
One of the most crucial T cell subsets in a variety of autoimmune and chronic inflammatory illnesses is T helper (Th) 17 cells. Th17 cells appear to...
-
Gene network analysis for identification of microRNA biomarkers for asthma
BackgroundTo date, reliable biomarkers for asthma have not been identified. MicroRNAs (miRNAs) are small, non-coding RNAs that negatively regulate...
-
Development of a Serum-Based MicroRNA Signature for Early Detection of Pancreatic Cancer: A Multicenter Cohort Study
BackgroundA grim prognosis of pancreatic cancer (PCa) was attributed to the difficulty in early diagnosis of the disease.
AimsIdentifying novel...
-
Drug resistance in breast cancer is based on the mechanism of exocrine non-coding RNA
Breast cancer (BC) ranks first among female malignant tumors and involves hormonal changes and genetic as well as environmental risk factors. In...
