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MiR-124-3p negatively impacts embryo implantation via suppressing uterine receptivity formation and embryo development
During embryo implantation, blastocyst interacts with the receptivity endometrium and the endometrial epithelium secretes nurturing fluid to support...
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miR-124-3p target genes identify globus pallidus role in suicide ideation recovery in borderline personality disorder
Borderline personality disorder (BPD) is characterized by patterns of unstable affect, unstable interpersonal relationships, and chronic suicidal...
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miR-124-3p sabotages lncRNA MALAT1 stability to repress chondrocyte pyroptosis and relieve cartilage injury in osteoarthritis
BackgroundOsteoarthritis (OA) is a prevalent inflammatory joint disorder. microRNAs (miRNAs) are increasingly involved in OA.
AimOur study is...
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PCGEM1 promotes cell proliferation and migration in endometriosis by targeting miR-124-3p-mediated ANTXR2 expression
BackgroundEndometriosis, a common gynaecological disease in women, affects 10% of women of childbearing age. Among infertile women, this proportion...
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HRCT1, negatively regulated by miR-124-3p, promotes tumor metastasis and the growth of gastric cancer by activating the ERBB2-MAPK pathway
BackgroundGastric cancer is the fourth leading cause of cancer-related deaths worldwide. And patient outcomes are poor due to tumor relapse and...
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EBF1-mediated up-regulation of lncRNA FGD5-AS1 facilitates osteosarcoma progression by regulating miR-124-3p/G3BP2 axis as a ceRNA
BackgroundAs a skeletal malignancy, osteosarcoma has high incidence among primary malignant bone tumors. With increasing researches on molecules...
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Expression levels of plasma exosomal miR-124, miR-125b, miR-133b, miR-130a and miR-125b-1-3p in severe asthma patients and normal individuals with emphasis on inflammatory factors
BackgroundIdentification of molecular markers, such as miRNAs is promising for the diagnosis of asthma and its clinical phenotypes. The aim of this...
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LLLI promotes BMSC proliferation through circRNA_0001052/miR-124-3p
Osteoporosis (OP) is a multifactorial bone disease that occurs worldwide. The treatment of OP is still unsatisfactory. Bone mesenchymal stem cell...
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MiR-124-3p reduces angiotensin II-dependent hypertension by down-regulating EGR1
Through previous literature studies, we found that miR-124-3p may be associated with hypertension. Therefore, we investigated the relationship...
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AKT2 drives cancer progression and is negatively modulated by miR-124 in human lung adenocarcinoma
BackgroundAKT2 is highly expressed in many human cancers, including non-small cell lung cancer (NSCLC). Accumulating evidence has also revealed that...
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SP1-activated long noncoding RNA lncRNA GCMA functions as a competing endogenous RNA to promote tumor metastasis by sponging miR-124 and miR-34a in gastric cancer
Long noncoding RNAs (lncRNAs) were demonstrated to play important roles in gene regulation and cancer progression. However, the functional roles of...
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Promoter methylation levels of microRNA-124 in non-neoplastic rectal mucosa as a potential biomarker for ulcerative colitis-associated colorectal cancer in pediatric-onset patients
PurposeTo determine the methylation level of the miR-124 promoter in non-neoplastic rectal mucosa of patients with pediatric-onset ulcerative colitis...
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Retraction Note: Sedum sarmentosum Bunge extract ameliorates lipopolysaccharide- and D-galactosamine-induced acute liver injury by attenuating the hedgehog signaling pathway via regulation of miR-124 expression
This article has been retracted. Please see the Retraction Notice for more detail: https://doi.org/10.1186/s12906-020-2873-1.
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Role of micro-RNAs 21, 124 and other novel biomarkers in distinguishing between group 1 WHO pulmonary hypertension and group 2, 3 WHO pulmonary hypertension
BackgroundPulmonary hypertension “PH” is considered a serious cardiovascular disease. World Health Organization divided PH into groups depending on...
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miR-124/VAMP3 is a novel therapeutic target for mitigation of surgical trauma-induced microglial activation
Activation of microglia and the subsequently elevated inflammatory cytokine release in the brain during surgery predispose individuals to cognitive...
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Long non-coding RNA nuclear paraspeckle assembly transcript 1 downregulation protects lens epithelial cells from oxidative stress-induced apoptosis by regulating the microRNA-124-3p/death-associated protein kinase 1 axis in age-related cataract
Oxidative stress plays a significant role in cataract development. It causes the apoptosis of lens epithelial cells (LECs), resulting in lens...
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RETRACTED ARTICLE: Sedum sarmentosum Bunge extract ameliorates lipopolysaccharide- and D-galactosamine-induced acute liver injury by attenuating the hedgehog signaling pathway via regulation of miR-124 expression
BackgroundSedum sarmentosum is traditionally used to treat various inflammatory diseases in China. It has protective effects against acute liver...
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Functional involvement of septal miR-132 in extinction and oxytocin-mediated reversal of social fear
Social interactions are critical for mammalian survival and evolution. Dysregulation of social behavior often leads to psychopathologies such as...
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Human Hematopoietic Stem Cells Co-cultured in 3D with Stromal Support to Optimize Lentiviral Vector-mediated Gene Transduction
HSC transplantation (HSCT) has emerged as a promising treatment option for hematological and immunological disorders. Unfortunately, many viral...
