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Effect of clinical decision support for severe hypercholesterolemia on low-density lipoprotein cholesterol levels
Severe hypercholesterolemia/possible familial hypercholesterolemia (FH) is relatively common but underdiagnosed and undertreated. We investigated...
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An increase in calculated small dense low-density lipoprotein cholesterol predicts new onset of hypertension in a Japanese cohort
A disorder of lipid metabolism is involved in cardiovascular diseases including hypertension. A high level of small dense low-density lipoprotein...
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Genetic variations of low-density lipoprotein cholesterol on metabolic disorders in obstructive sleep apnea
BackgroundThe study aimed to explore the relationship between low-density lipoprotein cholesterol (LDL-C) genetic variants and obstructive sleep...
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Effect of low-density lipoprotein level and mortality in older incident statin-naïve hemodialysis patients
BackgroundThis study aimed to analyze low-density lipoprotein cholesterol (LDL-C) levels and their relationship with mortality in order to identify...
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High-density lipoprotein, low-density lipoprotein and triglyceride levels and upper gastrointestinal cancers risk: a trans-ancestry Mendelian randomization study
ObjectiveThis study was conducted to explore the causal associations of high-density lipoprotein (HDL), low-density lipoprotein (LDL) and...
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Systolic blood pressure, low-density lipoprotein cholesterol levels, and adverse kidney outcome: results from KNOW-CKD
It is unknown whether intensive control of blood pressure (BP) and lipids can delay the progression of chronic kidney disease (CKD). This study...
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The association of cumulative low-density lipoprotein cholesterol exposure and carotid intima-media thickness in a young adulthood population
ObjectiveTo investigate the association between cumulative exposure to low-density lipoprotein cholesterol (LDL-C) and carotid intima-media thickness...
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Association between low-density lipoprotein cholesterol and sudden cardiac arrest in people with diabetes mellitus
BackgroundDyslipidemia measured as low-density lipoprotein (LDL)-cholesterol is an established risk factor of cardiovascular disease, which is more...
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Low-density lipoprotein cholesterol to apolipoprotein B ratio predicts mortality and cardiovascular events in peritoneal dialysis patients
PurposeThe ratio of low-density lipoprotein cholesterol (LDL-C)/apolipoprotein B (apo B) is associated with all-cause mortality and cardiovascular...
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The role of remnant cholesterol beyond low-density lipoprotein cholesterol in diabetes mellitus
BackgroundPrevious research has linked elevated low-density lipoprotein cholesterol (LDL-C) and remnant cholesterol (RC) with diabetes mellitus (DM)....
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The impact of statins treatments for plaque characteristics in stable angina pectoris patients with very low and high low-density lipoprotein cholesterol levels: an intracoronary optical coherence tomography study
Low-density lipoprotein cholesterol (LDL-C) levels are recommended according to the patient's risk factors based on guidelines. In patients achieving...
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Low-density lipoprotein cholesterol reduction with immediate combination therapy of statin and ezetimibe compared to statin monotherapy after percutaneous coronary intervention
BackgroundCurrent guidelines recommend a stepwise initiation of lipid-lowering therapy after percutaneous coronary interventions (PCI) in...
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New Strategies for Lowering Low-Density Lipoprotein Cholesterol for Cardiovascular Disease Prevention
Purpose of ReviewThe primary and secondary prevention of atherosclerotic cardiovascular disease (ASCVD) relies on optimizing cardiovascular health...
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Associations of preoperative serum high-density lipoprotein cholesterol and low-density lipoprotein cholesterol levels with the prognosis of ovarian cancer
BackgroundThe effect of serum lipids on ovarian cancer is controversial. We conducted this study to evaluate the prognostic value of preoperative...
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Procyanidin B2 alleviates oxidized low-density lipoprotein-induced cell injury, inflammation, monocyte chemotaxis, and oxidative stress by inhibiting the nuclear factor kappa-B pathway in human umbilical vein endothelial cells
BackgroundOxidized low-density lipoprotein (ox-LDL) can initiate and affect almost all atherosclerotic events including endothelial dysfunction. In...
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Benefits and Risks of Antihyperlipidemic Medication in Adults with Different Low-Density Lipoprotein Cholesterol Based on the Number Needed to Treat
PurposeThe objective of this investigation is to examine the benefits and potential risks of these drugs in individuals by varying baseline...
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Protective effects of paraoxonase-1, vitamin E and selenium, and oxidative stress index on the susceptibility of low density lipoprotein to oxidation in diabetic patients with/without coronary artery disease
BackgroundThe oxidative modification of low density lipoprotein (LDL) is closely associated with an increased risk for coronary artery disease (CAD)...
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Additive effect between homocysteine and low-density-lipoprotein cholesterol upon incidence of novel carotid plaque formation: data from a Chinese community-based cohort
ObjectiveHomocysteine (HCY) has been associated with carotid plaque in cross-sectional studies, but the prospective relationship between HCY and...
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Do Triglyceride-Rich Lipoproteins Equal Low-Density Lipoproteins in Risk of ASCVD?
Purpose of ReviewRecent large clinical trials have failed to show that triglyceride-rich lipoprotein-lowering therapies decrease the risk of...