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  1. Effect of clinical decision support for severe hypercholesterolemia on low-density lipoprotein cholesterol levels

    Severe hypercholesterolemia/possible familial hypercholesterolemia (FH) is relatively common but underdiagnosed and undertreated. We investigated...

    Hana Bangash, Seyedmohammad Saadatagah, ... Iftikhar J. Kullo in npj Digital Medicine
    Article Open access 18 March 2024
  2. An increase in calculated small dense low-density lipoprotein cholesterol predicts new onset of hypertension in a Japanese cohort

    A disorder of lipid metabolism is involved in cardiovascular diseases including hypertension. A high level of small dense low-density lipoprotein...

    Marenao Tanaka, Tatsuya Sato, ... Masato Furuhashi in Hypertension Research
    Article 02 August 2023
  3. Genetic variations of low-density lipoprotein cholesterol on metabolic disorders in obstructive sleep apnea

    Background

    The study aimed to explore the relationship between low-density lipoprotein cholesterol (LDL-C) genetic variants and obstructive sleep...

    Yu Peng, Hangdong Shen, ... Shankai Yin in Nutrition & Metabolism
    Article Open access 10 June 2024
  4. Effect of low-density lipoprotein level and mortality in older incident statin-naïve hemodialysis patients

    Background

    This study aimed to analyze low-density lipoprotein cholesterol (LDL-C) levels and their relationship with mortality in order to identify...

    Je Hun Song, Eun Hee Park, ... Kyung Don Yoo in BMC Nephrology
    Article Open access 02 October 2023
  5. High-density lipoprotein, low-density lipoprotein and triglyceride levels and upper gastrointestinal cancers risk: a trans-ancestry Mendelian randomization study

    Objective

    This study was conducted to explore the causal associations of high-density lipoprotein (HDL), low-density lipoprotein (LDL) and...

    Yanling Wu, Junyi **n, ... Zhengdong Zhang in European Journal of Clinical Nutrition
    Article 21 January 2022
  6. Systolic blood pressure, low-density lipoprotein cholesterol levels, and adverse kidney outcome: results from KNOW-CKD

    It is unknown whether intensive control of blood pressure (BP) and lipids can delay the progression of chronic kidney disease (CKD). This study...

    Kyung Won Kim, Hee Byung Koh, ... Seung Hyeok Han in Hypertension Research
    Article 27 February 2023
  7. The association of cumulative low-density lipoprotein cholesterol exposure and carotid intima-media thickness in a young adulthood population

    Objective

    To investigate the association between cumulative exposure to low-density lipoprotein cholesterol (LDL-C) and carotid intima-media thickness...

    Wei Huang, Weiqi Nie, ... Shouling Wu in BMC Cardiovascular Disorders
    Article Open access 24 June 2024
  8. Association between low-density lipoprotein cholesterol and sudden cardiac arrest in people with diabetes mellitus

    Background

    Dyslipidemia measured as low-density lipoprotein (LDL)-cholesterol is an established risk factor of cardiovascular disease, which is more...

    Yun Gi Kim, Joo Hee Jeong, ... Young-Hoon Kim in Cardiovascular Diabetology
    Article Open access 20 February 2023
  9. Low-density lipoprotein cholesterol to apolipoprotein B ratio predicts mortality and cardiovascular events in peritoneal dialysis patients

    Purpose

    The ratio of low-density lipoprotein cholesterol (LDL-C)/apolipoprotein B (apo B) is associated with all-cause mortality and cardiovascular...

    Chuanfei Zeng, Qing Zhan, ... **aojiang Zhan in International Urology and Nephrology
    Article 18 February 2023
  10. The role of remnant cholesterol beyond low-density lipoprotein cholesterol in diabetes mellitus

    Background

    Previous research has linked elevated low-density lipoprotein cholesterol (LDL-C) and remnant cholesterol (RC) with diabetes mellitus (DM)....

    **angming Hu, Qunzhi Liu, ... Ji** Lin in Cardiovascular Diabetology
    Article Open access 27 June 2022
  11. The impact of statins treatments for plaque characteristics in stable angina pectoris patients with very low and high low-density lipoprotein cholesterol levels: an intracoronary optical coherence tomography study

    Low-density lipoprotein cholesterol (LDL-C) levels are recommended according to the patient's risk factors based on guidelines. In patients achieving...

    Hideo Amano, Yoshimasa Kojima, ... Takanori Ikeda in Heart and Vessels
    Article 21 February 2024
  12. Low-density lipoprotein cholesterol reduction with immediate combination therapy of statin and ezetimibe compared to statin monotherapy after percutaneous coronary intervention

    Background

    Current guidelines recommend a stepwise initiation of lipid-lowering therapy after percutaneous coronary interventions (PCI) in...

    Achim Leo Burger, Nora Beran, ... Kurt Huber in Wiener klinische Wochenschrift
    Article 24 October 2023
  13. New Strategies for Lowering Low-Density Lipoprotein Cholesterol for Cardiovascular Disease Prevention

    Purpose of Review

    The primary and secondary prevention of atherosclerotic cardiovascular disease (ASCVD) relies on optimizing cardiovascular health...

    Sean Paul Gaine, Renato Quispe, ... Erin D. Michos in Current Cardiovascular Risk Reports
    Article 25 June 2022
  14. Associations of preoperative serum high-density lipoprotein cholesterol and low-density lipoprotein cholesterol levels with the prognosis of ovarian cancer

    Background

    The effect of serum lipids on ovarian cancer is controversial. We conducted this study to evaluate the prognostic value of preoperative...

    Qingqing Lin, Wenchao Liu, ... Li** Sun in Archives of Gynecology and Obstetrics
    Article 28 August 2021
  15. Procyanidin B2 alleviates oxidized low-density lipoprotein-induced cell injury, inflammation, monocyte chemotaxis, and oxidative stress by inhibiting the nuclear factor kappa-B pathway in human umbilical vein endothelial cells

    Background

    Oxidized low-density lipoprotein (ox-LDL) can initiate and affect almost all atherosclerotic events including endothelial dysfunction. In...

    Limei Yuan, Lihua Fan, ... Zhiguo Zhang in BMC Cardiovascular Disorders
    Article Open access 29 April 2024
  16. Benefits and Risks of Antihyperlipidemic Medication in Adults with Different Low-Density Lipoprotein Cholesterol Based on the Number Needed to Treat

    Purpose

    The objective of this investigation is to examine the benefits and potential risks of these drugs in individuals by varying baseline...

    Hong-Fei Wang, Yu-Cheng Mao, ... Qing-Bao Tian in American Journal of Cardiovascular Drugs
    Article 23 May 2024
  17. Protective effects of paraoxonase-1, vitamin E and selenium, and oxidative stress index on the susceptibility of low density lipoprotein to oxidation in diabetic patients with/without coronary artery disease

    Background

    The oxidative modification of low density lipoprotein (LDL) is closely associated with an increased risk for coronary artery disease (CAD)...

    Fatemeh Mehvari, Fatemeh Imanparast, ... Ali Khosrowbeygi in European Journal of Medical Research
    Article Open access 27 August 2023
  18. Additive effect between homocysteine and low-density-lipoprotein cholesterol upon incidence of novel carotid plaque formation: data from a Chinese community-based cohort

    Objective

    Homocysteine (HCY) has been associated with carotid plaque in cross-sectional studies, but the prospective relationship between HCY and...

    Mohetaboer Momin, Fangfang Fan, ... Yan Zhang in BMC Cardiovascular Disorders
    Article Open access 30 June 2023
  19. Do Triglyceride-Rich Lipoproteins Equal Low-Density Lipoproteins in Risk of ASCVD?

    Purpose of Review

    Recent large clinical trials have failed to show that triglyceride-rich lipoprotein-lowering therapies decrease the risk of...

    Benjamin N. Wadström, Anders B. Wulff, ... Børge G. Nordestgaard in Current Atherosclerosis Reports
    Article 28 September 2023
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