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Temporary hypothyroidism in severe crush syndrome: a potential novel entity
BackgroundThyroid hormone synthesis is a complex process in the human body. Although the thyroid gland is essential for thyroid hormone synthesis,...
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The relationship between thyroid and human-associated microbiota: A systematic review of reviews
In recent years, a growing number of studies have examined the relationship between thyroid pathophysiology and intestinal microbiota composition....
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Interrelationship between thyroid hormones and reduced renal function, a review article
BackgroundUnderstanding the relationship of thyroid hormones with the development of chronic kidney disease (CKD) has important clinical implications...
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The performance of levothyroxine tablet is impaired by bariatric surgery
ObjectiveThe aim was to evaluate if bariatric surgery can affect the LT4 performance. The endpoints were the following: 1) difference between LT4...
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Nonthyroidal illness syndrome in acute pancreatitis patients: an 8-year cohort study
BackgroundNonthyroidal illness syndrome (NTIS) is common in critical illness and is associated with poor prognosis. The aim of this study was to find...
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Promoter methylation changes in the placenta involved in the relationship between prenatal depression and small for gestational age
BackgroundRecent studies suggest that the incidence of small for gestational age (SGA) birth related to maternal depression, but the mechanism is...
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Role and Clinical Significance of Monocarboxylate Transporter 8 (MCT8) During Pregnancy
The review aims to summarize the available research focusing on the importance of monocarboxylate transporter ( MCT8 ) in thyroid hormone trafficking...
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Thyroid hormone action in epidermal development and homeostasis and its implications in the pathophysiology of the skin
Thyroid hormones (THs) are key endocrine regulators of tissue development and homeostasis. They are constantly released into the bloodstream and help...
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Adverse perinatal conditions and the developmental origins of thyroid dysfunction—Lessons from Animal Models
PurposeNutritional, hormonal, and environmental status during development can predispose the individual to obesity and endocrine diseases later in...
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Nonhuman primate genetic models for the study of rare diseases
Pre-clinical research and development relies heavily upon translationally valid models of disease. A major difficulty in understanding the biology...
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Thyroid Disease, Pregnancy, and Selenium Supplementation
Purpose of ReviewThyroid autoimmune disease is very common in women during their fertile age. From 2 to 17% of pregnant women in the general...
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Low urinary selenium levels are associated with iodine deficiency in Brazilian schoolchildren and adolescents
BackgroundSelenium (Se) and iodine (Io) are important micronutrients for the proper functioning of the thyroid gland, as they are crucial for the...
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Clinical recognition and evaluation of patients with inherited serum thyroid hormone-binding protein mutations
There are three important thyroid hormone-binding proteins in human serum, thyroxine-binding globulin, transthyretin, and albumin. Genetic variation...
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Analysis of metabolomics profile in hypothyroid patients before and after thyroid hormone replacement
PurposeThe serum metabolic changes occurring during the transition from hypothyroidism to euthyroidism are not known. This study aimed to determine...
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Genetics of primary congenital hypothyroidism—a review
PurposeCongenital primary hypothyroidism (CH) is a state of inadequate thyroid hormone production detected at birth, caused either by absent,...
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Atypical pituitary hormone-target tissue axis
A long-held belief is that pituitary hormones bind to their cognate receptors in classical target glands to actuate their manifold functions....
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Interconnection between circadian clocks and thyroid function
Circadian rhythmicity is an approximately 24-h cell-autonomous period driven by transcription–translation feedback loops of specific genes, which are...
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Thyroid hormone metabolites and analogues
Several metabolic products that derive from l -thyroxine (T4) and 3,3′5- l -triiodothyronine (T3), the main thyroid hormones secreted by the thyroid...
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Comparative assessment of gut microbial composition and function in patients with Graves’ disease and Graves’ orbitopathy
BackgroundA previous study indicated that gut microbiota changed notably in Graves’ orbitopathy (GO) patients as compared to controls. However, the...
