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Showing 1-15 of 15 results

  1. New concepts in regulation and function of the FGF23

    In comparison to the regulation of calcium homeostasis, which has been widely studied over the last several decades, phosphate homeostasis is little...

    Sanaz Dastghaib, Farhad Koohpeyma, ... Aliakbar Alizadeh in Clinical and Experimental Medicine
    Article 16 June 2022

  2. Research progress of fibroblast growth factor 23 in acute kidney injury

    Fibroblast growth factor 23 (FGF23) is primarily produced in bones and mainly regulates calcium and phosphorus metabolism. The level of circulating...

    Lina Zhang, Wei Qin in Pediatric Nephrology
    Article Open access 22 November 2022

  3. Skeletal endocrinology: where evolutionary advantage meets disease

    The regulation of whole-body homeostasis by the skeleton is mediated by its capacity to secrete endocrine signaling molecules. Although bone-derived...

    Nikolai Jaschke, Wolfgang Sipos, ... Martina Rauner in Bone Research
    Article Open access 28 May 2021

  4. FGF/FGFR signaling in health and disease

    Growing evidences suggest that the fibroblast growth factor/FGF receptor (FGF/FGFR) signaling has crucial roles in a multitude of processes during...

    Yangli **e, Nan Su, ... Lin Chen in Signal Transduction and Targeted Therapy
    Article Open access 02 September 2020

  5. Osteocyte Egln1/Phd2 links oxygen sensing and biomineralization via FGF23

    Osteocytes act within a hypoxic environment to control key steps in bone formation. FGF23, a critical phosphate-regulating hormone, is stimulated by...

    Megan L. Noonan, Pu Ni, ... Kenneth E. White in Bone Research
    Article Open access 18 January 2023

  6. Relationship between cFGF23/Klotho ratio and phosphate levels in patients with chronic kidney disease

    Purpose

    To characterize the relationship between the cFGF23/Klotho ratio and phosphate level in patients with chronic kidney disease (CKD).

    ...
    Zhongyan Liu, Hao Zhou, ... **g Zheng in International Urology and Nephrology
    Article 28 January 2019

  7. DMP1 prevents osteocyte alterations, FGF23 elevation and left ventricular hypertrophy in mice with chronic kidney disease

    During chronic kidney disease (CKD), alterations in bone and mineral metabolism include increased production of the hormone fibroblast growth factor...

    Corey Dussold, Claire Gerber, ... Aline Martin in Bone Research
    Article Open access 25 April 2019

  13. Klotho and fibroblast growth factor 23 in cerebrospinal fluid in children

    The fibroblast growth factor (FGF) 23/Klotho axis is a principal regulator of phosphate hemostasis and vitamin D metabolism, but limited data is...

    Svenja Kristin Kunert, Hans Hartmann, ... Maren Leifheit-Nestler in Journal of Bone and Mineral Metabolism
    Article 26 March 2016

  14. The PTH-Vitamin D-FGF23 axis

    Fibroblast growth factor 23 (FGF23) has emerged as an important regulator of phosphate and vitamin D homeostasis. It is important to understand how...

    Jenny E. Blau, Michael T. Collins in Reviews in Endocrine and Metabolic Disorders
    Article 01 June 2015
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