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Modified histopathological classification with age-related glomerulosclerosis for predicting kidney survival in ANCA-associated glomerulonephritis
BackgroundThe histopathological classification of ANCA-GN divides patients into four groups based on signs of glomerular injury. However, this...
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A case of idiopathic nodular glomerulosclerosis successfully treated by intensive blockade of the renin–angiotensin–aldosterone system
Idiopathic nodular glomerulosclerosis has a poor renal prognosis and is characterized by diffuse nodular glomerulosclerotic lesions in the absence of...
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Hidden genetics behind glomerular scars: an opportunity to understand the heterogeneity of focal segmental glomerulosclerosis?
Focal segmental glomerulosclerosis (FSGS) is a complex disease which describes different kinds of kidney defects, not exclusively linked with...
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Nephrotic syndrome due to focal segmental glomerulosclerosis complicating scleroderma: a case report
BackgroundSystemic scleroderma (SSc) is an insidious autoimmune connective tissue disorder with multiorgan involvement. Renal involvement is one of...
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A Case of Noncompaction Cardiomyopathy with Focal Segmental Glomerulosclerosis Treated with Combined Heart and Kidney Transplantation: a Case Report
Left ventricular noncompaction cardiomyopathy (LVNC) is a rare condition and a cause of heart failure and sudden cardiac death in young adults. It is...
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Familial focal segmental glomerulosclerosis with Alport-like glomerular basement changes caused by paired box protein 2 gene variant
Paired box protein 2 ( PAX2 ) gene variant causes renal coloboma syndrome (MIM#120330). Further, they are associated with focal segmental...
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Clinicopathological differences in focal segmental glomerulosclerosis depending on the accompanying pathophysiological conditions in renal allografts
Primary focal segmental glomerulosclerosis (FSGS) is thought to be caused by circulating factors leading to podocytopathy, whereas segmental...
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Ferroptosis-related genes, a novel therapeutic target for focal segmental glomerulosclerosis
Recent studies have suggested that ferroptosis participates in various renal diseases. However, its effect on focal segmental glomerulosclerosis...
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A clinicopathological and prognostic study of 18 children with C1q nephropathy and focal segmental glomerulosclerosis: an 18-year experience from a single center
BackgroundC1q nephropathy is a relatively rare glomerulonephritis characterized by dominant mesangial deposition of C1q. Even though C1q nephropathy...
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Focal segmental glomerulosclerosis in a patient with multiple sclerosis treated with Teriflunomide and Ocrelizumab
We describe the case of a 24-year-old male patient with multiple sclerosis (MS) who was treated with Teriflunomide for eight months. However, due to...
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Anterior and posterior ischemic optic neuropathy in a child with focal segmental glomerulosclerosis on hemodialysis
BackgroundIschemic optic neuropathy (ION) is exceedingly rare in children on dialysis, resulting from poor perfusion of the optic nerve, and presents...
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Non-glomerular Tip Lesion Focal Segmental Glomerulosclerosis as a Negative Predictor in Idiopathic Membranous Nephropathy
ObjectiveTo assess the significance of focal segmental glomerulosclerosis (FSGS) variants on clinicopathological characteristics and short-term...
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Post-operative recurrence of focal segmental glomerulosclerosis according to pre-transplant treatment after kidney transplantation
BackgroundRecurrent focal segmental glomerulosclerosis (FSGS) after kidney transplantation (KT) is a serious complication and a significant risk...
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Ocular manifestations of the genetic causes of focal and segmental glomerulosclerosis
Genetic forms of focal and segmental glomerulosclerosis (FSGS) often have extra-renal manifestations. This study examined FSGS-associated genes from...
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Kidney outcomes in children with primary focal segmental glomerulosclerosis from a low- and middle- income country
BackgroundLimited data exists regarding the clinical course and outcomes of children with primary focal segmental glomerulosclerosis (FSGS) from low-...
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WT1 exon 10 missense variant in a pediatric patient with focal segmental glomerulosclerosis with embryonal hyperplasia
A 6-year-old boy was diagnosed with chromosomal abnormalities (48,XYY, + 21[11]/46,XY[19]) at 4 months of age after a physical examination revealed...
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Development of a Conceptual Model for the Patient Experience of Focal Segmental Glomerulosclerosis (FSGS): A Qualitative Targeted Literature Review
IntroductionFocal segmental glomerulosclerosis (FSGS) is a leading cause of kidney disease and can progress to end stage kidney disease (ESKD). An...
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Marked reduction of proteinuria after removal of a growth hormone-producing pituitary adenoma in a patient with focal segmental glomerulosclerosis: a case report and literature review
Focal segmental glomerulosclerosis is a rare complication of acromegaly. A 74-year-old man was found to have acromegaly features such as enlargement...
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Anuria after kidney transplantation diagnosed as early recurrence of focal segmental glomerulosclerosis combined with acute calcineurin inhibitor nephrotoxicity: a case report and literature review
BackgroundPrimary focal segmental glomerulosclerosis (FSGS) is a glomerular disease that sometimes recurs in patients after kidney transplantation...
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CUBN gene mutations may cause focal segmental glomerulosclerosis (FSGS) in children
BackgroundImerslund-Gräsbeck Syndrome (IGS) is mainly caused by CUBN gene biallelic mutations. Proteinuria accompanies IGS specific symptoms in about...