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Incidence of heart valve disease in women treated with the ergot-derived dopamine agonist bromocriptine
BackgroundErgot-derived dopamine agonists are thought to induce fibrotic changes in cardiac valve leaflets. We sought to determine the incidence of...
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Unusual acute neonatal mortality and sow agalactia linked with ergot alkaloid contamination of feed
BackgroundAn increase in the occurrence of ergot alkaloid contamination has been observed in Europe in recent years. The typical clinical signs of...
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Treatment initiation for parkinson’s disease in Australia 2013–2018: a nation-wide study
BackgroundGuidelines highlight the importance of an individualized approach to treatment initiation for Parkinson’s disease. Our aim was to...
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Drug Safety in Episodic Migraine Management in Adults Part 1: Acute Treatments
Purpose of ReviewThe aim of this review is to aid in choosing safe options when assessing potential risks of acute migraine treatments based on known...
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Tolerability of non-ergot oral and transdermal dopamine agonists in younger and older Parkinson’s disease patients: an European multicentre survey
In older patients with Parkinson’s disease (PD), the use of dopamine agonists (DA) has been limited due to uncertainties related to their...
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Role of dopamine agonists in Parkinson's disease therapy
Dopamine agonists are an important component of Parkinson's therapy. When weighing up the various therapy options, therapy with levodopa has recently...
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Non-oral continuous drug delivery based therapies and sleep dysfunction in Parkinson’s disease
Continuous drug delivery (CDD) has emerged as a feasible and pragmatic therapeutic option for dopamine replacement therapy in advanced Parkinson’s...
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Acute Treatment Patterns, Migraine Burden, and Healthcare Resource Use in People With Migraine: Results From the OVERCOME (EU) Observational Study
IntroductionThe ObserVational survey of the Epidemiology, tReatment and Care Of MigrainE (OVERCOME) European Union (EU) is part of an overarching...
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Effects of rasagiline combined with levodopa and benserazide hydrochloride on motor function and homocysteine and IGF-1 levels in elderly patients with Parkinson’s disease
BackgroundDuring the course of their illness, people with Parkinson’s disease may see changes in their insulin-like growth factor (IGF-1) and serum...
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Medieval surgery (eleventh–thirteenth century): barber surgeons and warfare surgeons in France
PurposeFrom the eleventh to the thirteenth century, three major events marked surgery in France: the appearance of an epidemic linked to ergotism...
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How to manage intolerance to dopamine agonist in patients with prolactinoma
PurposeDopamine agonists (DA) are the gold-standard for prolactinoma and hyperprolactinemia treatment. Intolerance to DA leading to drug drop out...
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Ergotism in feedlot cattle: clinical, hematological, and pathological findings
Consumption of grains, contaminated with Claviceps purpurea , may cause ergotism in animals. Ruminants are considered relatively sensitive to...
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Treatment patterns for patients initiating novel acute migraine specific medications (nAMSMs) in the context of monoclonal antibodies (mAbs) targeting the calcitonin gene-related peptide (CGRP) pathway
BackgroundNew acute and preventive migraine medications are available, but data on current treatment patterns are limited. This study describes...
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Addressing the cost of chronic and episodic migraine and its main drivers: a short-term longitudinal analysis from a third-level Italian center
BackgroundChronic migraine (CM) is one of the most disabling neurological diseases, often associated to medication overuse headache (MOH). These...
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Long-term treatment with lasmiditan in patients with migraine: post hoc analysis of treatment patterns and outcomes from the open-label extension of the CENTURION randomized trial
BackgroundThe objective of this analysis was to gain new insights into the patient characteristics and other factors associated with lasmiditan usage...
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Sex differences in the clinical manifestations related to dependence behaviors in medication-overuse headache
ObjectiveThe present study aimed to compare sex differences in the clinical manifestations related to dependence behaviors in medication-overuse...
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Off-time Treatment Options for Parkinson’s Disease
Motor fluctuations (MF) are deemed by patients with Parkinson's disease (PD) as the most troublesome disease feature resulting from the increasing...
