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e-Consent in UK academic-led clinical trials: current practice, challenges and the need for more evidence
BackgroundDuring the COVID-19 pandemic, in-person healthcare visits were reduced. Consequently, trial teams needed to consider implementing remote...
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E-Consent—a guide to maintain recruitment in clinical trials during the COVID-19 pandemic
BackgroundThe COVID-19 pandemic has posed daunting challenges when conducting clinical research. Adopting new technologies such as remote electronic...
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The use of e-consent in surgery and application to neurosurgery: a systematic review and meta-analysis
IntroductionThe integration of novel electronic informed consent platforms in healthcare has undergone significant growth over the last decade....
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Electronic informed consent: effects on enrolment, practical and economic benefits, challenges, and drawbacks—a systematic review of studies within randomized controlled trials
BackgroundEnrolment is one of the most challenging aspects of conducting clinical trials, preceded by the process of informed consent (IC). Different...
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Quantitative analysis of a rare disease network’s international contact database and E-repository provides insights into biobanking in the electronic consent era
BackgroundCastleman disease (CD) describes a group of rare and poorly understood lymphoproliferative disorders that include unicentric CD (UCD),...
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The AlzMatch Pilot Study - Feasibility of Remote Blood Collection of Plasma Biomarkers for Preclinical Alzheimer’s Disease Trials
BackgroundAdvances in plasma biomarkers to detect Alzheimer’s disease (AD) biology allows researchers to improve the efficiency of participant...
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Legal issues in digital oral health: a sco** review
BackgroundThis sco** review aims to systematically and critically describe the numerous legal challenges brought about by the utilization of...
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Correlation Between Nasal Allergy and the Number of Eosinophils in Adenoid Tissue
To study adenoid tissue eosinophilia in allergic rhinitis. A single-centre clinical case–control prospective study with 66 subjects enrolled for the...
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Effectiveness of nicotine salt vapes, cytisine, and a combination of these products, for smoking cessation in New Zealand: protocol for a three-arm, pragmatic, community-based randomised controlled trial
BackgroundCombining short-acting nicotine replacement therapy with varenicline increases smoking cessation rates compared with varenicline alone, but...
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Study protocol for two pilot randomised controlled trials aimed at increasing physical activity using electrically assisted bicycles to enhance prostate or breast cancer survival
BackgroundIn 2020, 1.4 and 2.3 million new cases of prostate cancer and breast cancer respectively were diagnosed globally. In the UK, prostate...
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Digital consent in gynecology: an evaluation of patient experience
IntroductionThe surgical consent process is a crucial discussion between patient and surgeon, which is predominantly documented utilizing...
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Evaluation the quality of bag-mask ventilation by E/C, T/E and hook technique (a new proposed technique)
BackgroundBag-Mask Ventilation (BMV) is a crucial skill in managing emergency airway situations and induction of general anesthesia. Ensuring...
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Myocardial performance imaging for the early identification of cardiac dysfunction in neonates with sepsis
PurposeThe assessment of cardiac performance in septic new-borns is crucial for detecting hemodynamic instability and predicting outcome. The aim of...
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Protocol implementation during the COVID-19 pandemic: experiences from a randomized trial of stress ulcer prophylaxis
BackgroundDuring the COVID-19 pandemic, many intensive care units (ICUs) halted research to focus on COVID-19-specific studies.
Objective ...
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Laparoscopic modified e-tep repair of concomitant inguinal and ventral hernias
BackgroundLaparoscopic hernia repair in recent times has gained the most acceptance among both the surgical community and the patient groups, as it...
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A multicenter prospective randomized controlled trial investigating the effects of combustion-free nicotine alternatives on cardiovascular risk factors and metabolic parameters in individuals with type 2 diabetes who smoke: the DiaSmokeFree study protocol
Stop** smoking is crucial for public health and especially for individuals with diabetes. Combustion-free nicotine alternatives like e-cigarettes...
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Awareness and use of tobacco products among underage individuals: findings from the altria client services underage tobacco use survey 2020–2022
BackgroundTobacco use among underage individuals is a public health concern. Timely data about tobacco products, especially emerging products such as...
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Randomized Evaluation of Surgery in Elderly with Traumatic Acute SubDural Hematoma (RESET-ASDH trial): study protocol for a pragmatic randomized controlled trial with multicenter parallel group design
BackgroundThe rapidly increasing number of elderly (≥ 65 years old) with TBI is accompanied by substantial medical and economic consequences. An ASDH...
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Hypnosis in the operating room: are anesthesiology teams interested and well-informed?
BackgroundHypnosis can be a beneficial complementary anesthesia technique for a variety of surgical procedures. Despite favorable scientific...
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Sleep disorders in patients with endometriosis; a cross-sectional study
BackgroundEndometriosis affects 10–15% of women of reproductive age and is considered a critical gynecological problem. Endometriosis causes pain and...