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1. Anaphylactic Responses to Neuromuscular Blockade Drugs and Reversal Drugs

   Purpose of Review

   This review discusses the incidence of anaphylaxis to neuromuscular blockade drugs (NMBDs), the mechanism and clinical features, as...

   Alice C. Quayle, Tim M. Cook in Current Anesthesiology Reports

   Article 09 September 2023
   

2. Drugs in Human Milk Part 1: Practical and Analytical Considerations in Measuring Drugs and Metabolites in Human Milk

   Human milk is a remarkable biofluid that provides essential nutrients and immune protection to newborns. Breastfeeding women consuming medications...

   Osama Y. Alshogran, Prerna Dodeja, ... Raman Venkataramanan in Clinical Pharmacokinetics

   Article 15 May 2024
   

3. The Pharmacokinetics and Target Attainment of Antimicrobial Drugs Throughout Pregnancy: Part III Non-penicillin and Non-cephalosporin Drugs

   Introduction

   Understanding the pharmacokinetics (PK) of antimicrobial drugs in pregnant women is crucial to provide effective and safe treatment. This...

   F. Groen, J. R. Prins, ... P. Mian in Clinical Pharmacokinetics

   Article Open access 20 March 2023
   

4. Police seizure of drugs without arrest among people who use drugs in Vancouver, Canada, before provincial ‘decriminalization’ of simple possession: a cohort study

   Background

   Several jurisdictions in Canada have recently considered decriminalizing possession of illicit drugs for personal use (henceforth, simple...

   Kanna Hayashi, Tyson Singh Kelsall, ... Thomas Kerr in Harm Reduction Journal

   Article Open access 30 August 2023

5. Anticholinergic drugs for parkinsonism and other movement disorders

   Anticholinergic (AC) drugs, a medication class that acts by blocking nicotinic and muscarinic acetylcholine receptors, were first utilized for...

   Peter A. LeWitt, Luke Hong, Mark S. Moehle in Journal of Neural Transmission

   Article 21 June 2024

6. Designing combinational herbal drugs based on target space analysis

   Background

   Traditional oriental medicines (TOMs) are a medical practice that follows different philosophies to pharmaceutical drugs and they have been...

   Assefa Mussa Woyessa, Lemessa Etana Bultum, Doheon Lee in BMC Complementary Medicine and Therapies

   Article Open access 01 May 2024
   

7. Bioavailability of Orally Administered Drugs After Bariatric Surgery

   Purpose of Review

   Oral drug absorption after bariatric surgery is likely to be altered, but the impact of different bariatric surgery procedures on...

   Eliška Dvořáčková, Alena Pilková, ... Jan Miroslav Hartinger in Current Obesity Reports

   Article 03 January 2024
   

8. Neuro-ophthalmic complications of modern anti-cancer drugs

   Purpose

   Targeted cancer therapies have been responsible for a dramatic shift in treatment strategies for cancer, and the number of drugs, classes, and...

   Joshua A. Oskam, Helen V. Danesh-Meyer in Graefe's Archive for Clinical and Experimental Ophthalmology

   Article Open access 12 February 2024
   

9. People Who Inject Drugs in Mozambique: We need to normalize HIV treatment and care services in specialized community centers for people who inject drugs!

   Globally, People Who Inject Drugs (PWID) have limited healthcare, treatment, and prevention services, and they frequently experience stigma and...

   Cynthia Semá Baltazar, Auria Ribeiro Banze, ... Makini Boothe in Harm Reduction Journal

   Article Open access 06 January 2024

10. HTA Barriers for Conditional Approval Drugs

    Background

    Conditional approval pathways facilitate accelerated marketing authorisation based on immature clinical evidence for drugs that address an...

    Mackenzie Mills in PharmacoEconomics

    Article 23 February 2023
    

11. Implementation status of pharmacological studies in the development of orphan drugs

    Background

    The nonclinical as well as clinical development of orphan drugs is difficult, owing to unknown pathophysiology and the absence of animal...

    Saki Yokoshiki, Teruyo Arato in Orphanet Journal of Rare Diseases

    Article Open access 02 January 2024
    

12. Senolytic Drugs: Implications for Clinical Practice

    Abstract

    Studying the mechanisms of aging is one of the most important goals of modern science. A significant amount of data on the processes...

    A. K. Ilyushchenko, L. V. Matchekhina, ... I. D. Strazhesko in Advances in Gerontology

    Article 01 June 2023
    

13. “2.5 g, I could do that before noon”: a qualitative study on people who use drugs’ perspectives on the impacts of British Columbia’s decriminalization of illegal drugs threshold limit

    Background

    In May 2022, Health Canada approved a three-year exemption from the Controlled Drugs and Substances Act decriminalizing possession of...

    Farihah Ali, Cayley Russell, ... Jürgen Rehm in Substance Abuse Treatment, Prevention, and Policy

    Article Open access 15 June 2023

14. Postmortem redistribution of drugs: a literature review

    Postmortem drug analysis is crucial in identifying the potential cause and manner of death. However, it is threatened by a significant phenomenon...

    Ghadeer M. M. Abdelaal, Nagah I. Hegazy, ... Ghada E. A. Elmesallamy in Forensic Science, Medicine and Pathology

    Article Open access 16 September 2023

15. Psychoactive drugs and male fertility: impacts and mechanisms

    Although psychoactive drugs have their therapeutic values, they have been implicated in the pathogenesis of male infertility. This study highlights...

    Moses Agbomhere Hamed, Victor Olukayode Ekundina, Roland Eghoghosoa Akhigbe in Reproductive Biology and Endocrinology

    Article Open access 28 July 2023
    

16. Pharmacological fingerprint of antipsychotic drugs at the serotonin 5-HT_2A receptor

    The intricate involvement of the serotonin 5-HT _2A receptor (5-HT _2A R) both in schizophrenia and in the activity of antipsychotic drugs is widely...

    Supriya A. Gaitonde, Charlotte Avet, ... Michel Bouvier in Molecular Psychiatry

    Article Open access 02 April 2024
    

17. Do generic drugs cause hypersensitivity?

    Generic drugs may differ from brand-name drugs in nature and quantity of excipients. Hypersensitivity to generic drugs is a subject of growing...

    Florence Tetart, Henri Gonde, Charles Hervouët in European Journal of Dermatology

    Article 01 September 2022

18. A new score for predicting intracranial hemorrhage in patients using antiplatelet drugs

    Antiplatelet drugs in patients increase the risk of intracranial hemorrhage (ICH), which can seriously affect patients’ quality of life and even...

    Fuxin Ma, Zhiwei Zeng, ... **hua Zhang in Annals of Hematology

    Article 17 April 2024
    

19. Incomplete Data and Potential Risks of Drugs in People with Obesity

    Purpose of Review

    To provide examples of knowledge gaps in current pharmaceutical treatments for people with obesity and call for changes to...

    Caroline M. Apovian, Christopher D. Bruno, ... David J. Greenblatt in Current Obesity Reports

    Article Open access 18 November 2023
    

20. Potentially Inappropriate Psychotropic Drugs in Nursing Homes: An Italian Observational Study

    Background and objectives

    Physicians often face difficulties in selecting appropriate medications for older adults with multiple comorbidities. As...

    Marina Azab, Alessio Novella, ... Luca Pasina in Drugs & Aging

    Article 30 November 2023