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  1. TRAIL inhibition by soluble death receptor 5 protects against acute myocardial infarction in rats

    Acute myocardial infarction (AMI) is associated with high morbidity and mortality. An effective therapeutic strategy is to rescue cardiomyocytes from...

    Mingli Wang, Yinxiang Wei, ... Yuanfang Ma in Heart and Vessels
    Article 07 November 2022
  2. Duck Tembusu virus infection induces mitochondrial-mediated and death receptor-mediated apoptosis in duck embryo fibroblasts

    Duck Tembusu virus (DTMUV) is a pathogenic flavivirus that has caused enormous economic losses in Southeast Asia. Our previous study showed that...

    Yuhong Pan, Wenjun Cai, ... Renyong Jia in Veterinary Research
    Article Open access 07 July 2022
  3. Leukocyte-associated immunoglobulin-like receptor-1 blockade in combination with programmed death-ligand 1 targeting therapy mediates increased tumour control in mice

    Collagen expression and structure in the tumour microenvironment are associated with tumour development and therapy response. Leukocyte-associated...

    Akashdip Singh, Eline T. A. M. Mommers-Elshof, ... M. Ines Pascoal Ramos in Cancer Immunology, Immunotherapy
    Article Open access 18 January 2024
  4. Negligible role of TRAIL death receptors in cell death upon endoplasmic reticulum stress in B-cell malignancies

    Impairments in protein folding in the endoplasmic reticulum (ER) lead to a condition called ER stress, which can trigger apoptosis via the...

    Francesca Favaro, Demi Both, ... Eric Eldering in Oncogenesis
    Article Open access 08 February 2023
  5. Gene expression of programmed cell death ligand-1 (PDL-1) and vitamin D receptor (VDR) with the serum vitamin D3 in lung cancer

    Background

    Lung cancer (LC) is one of the leading causes of death worldwide. Programmed cell death receptor 1 (PD-1) interacts with its ligand (PDL-1)...

    Ragaa H. M. Salama, Soad M. A. Faied, ... Marwa A. Dahpy in The Egyptian Journal of Bronchology
    Article Open access 09 December 2022
  6. Blood pressure-lowering effects of SGLT2 inhibitors and GLP-1 receptor agonists for preventing of cardiovascular events and death in type 2 diabetes: a systematic review and meta-analysis

    Aims

    To investigate the lowering BP effects of sodium glucose cotransporter 2 inhibitors (SGLT2i) and glucagon-like peptide 1 receptor agonists (GLP-1...

    Alhassane Diallo, Miguel Carlos-Bolumbu, Florence Galtier in Acta Diabetologica
    Article 13 July 2023
  7. Hsp90α and cell death in cancers: a review

    Heat shock protein 90α (Hsp90α), an important molecular chaperone, plays a crucial role in regulating the activity of various intracellular signaling...

    Bin Liu, Daohai Qian in Discover Oncology
    Article Open access 10 May 2024
  8. Arginine methylation of caspase-8 controls life/death decisions in extrinsic apoptotic networks

    Procaspase-8 is a key mediator of death receptor (DR)-mediated pathways. Recently, the role of post-translational modifications (PTMs) of...

    Fabian Wohlfromm, Nikita V. Ivanisenko, ... Inna N. Lavrik in Oncogene
    Article Open access 10 May 2024
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