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Weighing Risks and Benefits in the Presence of Competing Risks
Purpose of ReviewWhen competing events occur, there are two main options for handling them analytically that invoke different assumptions: 1) censor...
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Systematic comparison of approaches to analyze clustered competing risks data
BackgroundIn many clinical trials the study interest lies in the comparison of a treatment to a control group regarding a time to event endpoint like...
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Competing-risks model for predicting the prognosis of patients with angiosarcoma based on the SEER database of 3905 cases
PurposeTo establish a competing-risks model and compare it with traditional survival analysis, aiming to identify more precise prognostic factors for...
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The importance of considering competing risks in recurrence analysis of intracranial meningioma
BackgroundThe risk of recurrence is overestimated by the Kaplan–Meier method when competing events, such as death without recurrence, are present....
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Application and subgroup analysis of competing risks model based on different lymph node staging systems in differentiated thyroid cancer
Differentiated thyroid cancer (DTC) is the most common endocrine malignancy, with a rising incidence worldwide. Accurate prognostic models are...
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Competing-risks analysis for evaluating the prognosis of patients with microinvasive cutaneous squamous cell carcinoma based on the SEER database
BackgroundUtilizing the traditional Cox regression model to identify the factors affecting the risk of mortality due to microinvasive cutaneous...
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Competing risks analysis for neutrophil to lymphocyte ratio as a predictor of diabetic retinopathy incidence in the Scottish population
BackgroundDiabetic retinopathy (DR) is a major sight-threatening microvascular complication in individuals with diabetes. Systemic inflammation...
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Statistical models versus machine learning for competing risks: development and validation of prognostic models
BackgroundIn health research, several chronic diseases are susceptible to competing risks (CRs). Initially, statistical models (SM) were developed to...
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Long-term outcomes of 5-year survivors without recurrence after the complete resection of non-small cell lung cancer after lobectomy: a landmark analysis in consideration of competing risks
PurposeAmong non-small cell lung cancers (NSCLC), 5 years is a benchmark in cancer control and treatment, but a certain percentage of cases recur...
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The use of adjuvant chemotherapy is not associated with recurrence or cancer-specific death following curative resection for stage III rectal cancer: a competing risks analysis
BackgroundThe role of adjuvant chemotherapy (AC) in stage III rectal cancer (RC) has been argued based on evidence from its use in colon cancer....
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A multistate competing risks framework for preconception prediction of pregnancy outcomes
BackgroundPreconception pregnancy risk profiles—characterizing the likelihood that a pregnancy attempt results in a full-term birth, preterm birth,...
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Evaluation of laboratory values affecting mortality of end-stage renal disease patients: a competing risks approach
BackgroundChronic Kidney Disease (CKD) is a prevalent and life-threatening situation recognized as an emerging health issue. The present study aimed...
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Competing risks analysis of external versus internal radiation in patients with hepatocellular carcinoma after controlling for immortal time bias
PurposeIn cohort studies on liver cancer, there are often immortal time bias and interference of competing risk events. This study proposes to...
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Competing Benefits and Competing Hazards: The Benefit to Harm Balance in Individual Patients in Rational Therapeutics
For any therapeutic intervention in an individual, there is a balance between the potential benefits and the possible harms. The extent to which the...
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Joint modelling with competing risks of dropout for longitudinal analysis of health-related quality of life in cancer clinical trials
PurposeHealth-related quality of life (HRQoL) is an important endpoint in cancer clinical trials. Analysis of HRQoL longitudinal data is plagued by...
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Prostate cancer mortality rates in low- and favorable intermediate-risk active surveillance patients: a population-based competing risks analysis
PurposeTo determine prostate cancer (PCa) and other-cause mortality rates in low- and favorable intermediate-risk (FIR) active surveillance (AS)...
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An external validation of the Kidney Donor Risk Index in the UK transplant population in the presence of semi-competing events
BackgroundTransplantation represents the optimal treatment for many patients with end-stage kidney disease. When a donor kidney is available to a...
