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Blunted circadian variation of blood pressure in individuals with neurofibromatosis type 1
BackgroundCardiovascular events such as myocardial infarction and stroke are life-threatening complications associated with Neurofibromatosis type 1...
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Association between circadian variation of heart rate and mortality among critically ill patients: a retrospective cohort study
BackgroundHeart rate (HR) related parameters, such as HR variability, HR turbulence, resting HR, and nighttime mean HR have been recognized as...
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The intersection between ghrelin, metabolism and circadian rhythms
Despite the growing popular interest in sleep and diet, many gaps exist in our scientific understanding of the interaction between circadian rhythms...
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Circadian rhythm, ipRGCs, and dopamine signalling in myopia
Myopia, a common ophthalmic disorder, places a high economic burden on individuals and society. Genetic and environmental factors influence myopia...
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Circadian Advantages in Elite Athletes
Purpose of ReviewThis review discusses the opportunities and challenges of training and competing “around the clock.”
Recent Findings ... -
Circadian Factors in Stroke: A Clinician’s Perspective
Stroke remains one of the leading causes of mortality and long-term and permanent disability worldwide despite technological innovations and...
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The history of circadian rhythm research in Austria
In view of the recent revival of interest in circadian biology and circadian epidemiology at the Medical University of Vienna, it seems appropriate...
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A longitudinal study of blood pressure circadian rhythm from childhood to early adulthood
Altered blood pressure (BP) circadian rhythmicity has been increasingly linked with cardiovascular risk. However, little is known about BP circadian...
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Circadian, Reward, and Emotion Systems in Teens prospective longitudinal study: protocol overview of an integrative reward-circadian rhythm model of first onset of bipolar spectrum disorder in adolescence
BackgroundBipolar spectrum disorders (BSDs) are associated with a heightened sensitivity to rewards and elevated reward-related brain function in...
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Molecular mechanisms of tumour development in glioblastoma: an emerging role for the circadian clock
Glioblastoma is one of the most lethal cancers with current therapeutic options lacking major successes. This underlines the necessity to understand...
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Pressure Building Against the Clock: The Impact of Circadian Misalignment on Blood Pressure
Purpose of ReviewMisalignment between the endogenous biological timing system and behavioral activities (i.e., sleep/wake, eating, activity)...
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Circadian rhythm analysis using wearable-based accelerometry as a digital biomarker of aging and healthspan
Recognizing the pivotal role of circadian rhythm in the human aging process and its scalability through wearables, we introduce CosinorAge, a digital...
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Peripheral immune circadian variation, synchronisation and possible dysrhythmia in established type 1 diabetes
Aims/hypothesisThe circadian clock influences both diabetes and immunity. Our goal in this study was to characterise more thoroughly the circadian...
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Effects of Mood Stabilizers on Sleep and Circadian Rhythms: A Systematic Review
Purpose of ReviewMood disorders tend to be recurrent, chronic, and disabling, caused by a complex interplay of factors. Within this context, sleep,...
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Approaches for Assessing Circadian Rest-Activity Patterns Using Actigraphy in Cohort and Population-Based Studies
Purpose of ReviewTo review methods for analyzing circadian rest-activity patterns using actigraphy and to discuss their applications in large cohort...
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Targeting sleep and the circadian system as a novel treatment strategy for Parkinson’s disease
There is a growing appreciation of the wide range of sleep–wake disturbances that occur frequently in Parkinson’s disease. These are known to be...
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Circadian temperature rhythm in breeding sows: differences between days in oestrus and anoestrus after weaning
BackgroundMammals are subject to circadian rhythms for the control of various physiological events. One of the parameters known to be subject to...
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Circadian rhythms of melatonin and its relationship with anhedonia in patients with mood disorders: a cross-sectional study
BackgroundMood disorders are strongly associated with melatonin disturbances. However, it is unclear whether there is a difference in melatonin...
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The role of insufficient sleep and circadian misalignment in obesity
Traditional risk factors for obesity and the metabolic syndrome, such as excess energy intake and lack of physical activity, cannot fully explain the...
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Association between circadian physical activity patterns and mortality in the UK Biobank
BackgroundThe benefit of physical activity (PA) for increasing longevity is well-established, however, the impact of diurnal timing of PA on...