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Chemoprevention—Historical Perspectives and Current Trends
Purpose of ReviewTo explore the landmark clinical trials which shaped contemporary chemoprevention practice, discuss trends in chemoprevention...
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Chemoprevention in hepatocellular carcinoma
Purpose of ReviewThe number of deaths due to hepatocellular carcinoma (HCC) continues to rise. Chemoprevention may be a useful strategy to prevent...
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Cancer metastasis chemoprevention prevents circulating tumour cells from germination
The war against cancer traces back to the signature event half-a-century ago when the US National Cancer Act was signed into law. The cancer crusade...
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Contraception as chemoprevention of ovarian cancer in BRCA1 and BRCA2 women
Ovarian cancer is the seventh most common cancer in women in the world, with an estimated worldwide mortality of over 207′000 women every year. This...
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Household-level effects of seasonal malaria chemoprevention in the Gambia
BackgroundIn 2022 the WHO recommended the discretionary expansion of the eligible age range for seasonal malaria chemoprevention (SMC) to children...
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Qualitative analysis of shared decision-making for chemoprevention in the primary care setting: provider-related barriers
BackgroundChemoprevention with anti-estrogens, such as tamoxifen, raloxifene or aromatase inhibitors, have been shown to reduce breast cancer risk in...
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Affect regulation as a moderator of intentions for breast cancer chemoprevention
Women at high risk for breast cancer (BC) may consider chemoprevention for risk reduction, but uptake is low. This study examined the role of affect...
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Initiation and tolerance of chemoprevention among women with high-risk breast lesions: the potential of low-dose tamoxifen
PurposeHigh-risk lesions (HRLs) of the breast are an indication for chemoprevention, yet uptake is low, largely due to concerns about side effects....
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Seasonal malaria chemoprevention in Africa and China’s upgraded role as a contributor: a sco** review
BackgroundChildren under five are the vulnerable population most at risk of being infected with Plasmodium parasites, especially in the Sahel...
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Cancer chemoprevention through Frizzled receptors and EMT
Frizzled (FZD) transmembrane receptors are well known for their role in β-catenin signaling and development and now understanding of their role in...
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Coverage of seasonal malaria chemoprevention in children aged 3 to 59 months in Burkina Faso: a nationwide cross-sectional study
AimThe objective of this study was to investigate seasonal malaria chemoprevention (SMC) coverage during the 2018 campaign and to identify factors...
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Precision and Immunoprevention Strategies for Tobacco-Related Head and Neck Cancer Chemoprevention
To date, there is no FDA-approved chemoprevention approach for tobacco-related HNSCC. Effective chemoprevention approaches validated in sufficiently...
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Dihydroartemisinin-piperaquine or sulphadoxine-pyrimethamine for the chemoprevention of malaria in children with sickle cell anaemia in eastern and southern Africa (CHEMCHA): a protocol for a multi-centre, two-arm, double-blind, randomised, placebo-controlled superiority trial
BackgroundAn estimated 300,000 babies are born with sickle cell anaemia (SCA) annually. Affected children have chronic ill health and suffer...
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Co-implementing vitamin A supplementation with seasonal malaria chemoprevention in Sokoto State, Nigeria: a feasibility and acceptability study
BackgroundBi-annual high dose vitamin A supplements administered to children aged 6–59 months can significantly reduce child mortality, but vitamin A...
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Updates in Chemoprevention Research for Hereditary Gastrointestinal and Polyposis Syndromes
Purpose of reviewTo critically examine recently published research in the area of chemoprevention in hereditary polyposis and gastrointestinal...
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Chemoprevention for Colorectal Cancers: Are Chemopreventive Effects Different Between Left and Right Sided Colorectal Cancers?
Background and AimsRecent studies have suggested that right- and left-sided colorectal cancers (CRCs) are molecularly distinct. In this study, we...
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Understanding low chemoprevention uptake by women at high risk of breast cancer: findings from a qualitative inductive study of women’s risk-reduction experiences
BackgroundChemoprevention is one of several methods that have been developed to help high-risk women reduce their risk of breast cancer. Reasons for...
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Using systems thinking to understand the scale-up and sustainability of health innovation: a case study of seasonal malaria chemoprevention processes in Burkina Faso
BackgroundScale-up and sustainability are often studied separately, with few studies examining the interdependencies between these two processes and...
