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Traumatic Brain Injury
In spite of great improvements in prehospital, critical care, and surgical management, traumatic brain injury is still a leading cause of death and...
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Utility of brain imaging in pediatric patients with a suspected accidental spinal injury but no brain injury-related symptoms
PurposeImaging is the gold standard in diagnosing traumatic brain injury, but unnecessary scans should be avoided, especially in children and...
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Bilateral vertebral artery injury leads to brain death following traumatic brain injury: a case report
BackgroundVertebral artery injury is a rare condition in trauma settings. In the advanced stages, it causes death.
CaseA 31-year-old Sundanese woman...
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Cardiac Injury After Traumatic Brain Injury: Clinical Consequences and Management
Traumatic brain injury (TBI) is a significant public health issue because of its increasing incidence and the substantial short-term and long-term...
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Brain retraction injury: systematic literature review
Cerebral retraction is frequently required in cranial surgery to access deep areas. Brain retractors have been systematically used in the past, but...
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Structural Brain Injury on Brain Magnetic Resonance Imaging in Acute Respiratory Distress Syndrome
BackgroundAcute respiratory distress syndrome (ARDS) is an acute inflammatory respiratory failure condition that may be associated with brain injury....
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Pathophysiology of acute lung injury in patients with acute brain injury: the triple-hit hypothesis
It has been convincingly demonstrated in recent years that isolated acute brain injury (ABI) may cause severe dysfunction of peripheral extracranial...
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Brain Oxygenation Response to Hypercapnia in Patients with Acute Brain Injury
BackgroundCerebral hypoxia is a frequent cause of secondary brain damage in patients with acute brain injury. Although hypercapnia can increase...
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Potential biomarkers in hypoglycemic brain injury
Oxidative stress is a major underlying mechanism in hypoglycemic brain injury. Several oxidative stress–related proteins were identified through...
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Neurophysiologic Features Reflecting Brain Injury During Pediatric ECMO Support
BackgroundExtracorporeal membrane oxygenation (ECMO) provides lifesaving support to critically ill patients who experience refractory cardiopulmonary...
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Ferroptosis in early brain injury after subarachnoid hemorrhage: review of literature
Spontaneous subarachnoid hemorrhage (SAH), mainly caused by ruptured intracranial aneurysms, is a serious acute cerebrovascular disease. Early brain...
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Accuracy of acute hyperglycemia as a biomarker of severe brain damage in children with traumatic brain injury
PurposeBiomarkers are substances measured at the systemic level to evaluate organic responses in certain situations, establishing diagnoses, disease...
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From spreading depolarization to blood–brain barrier dysfunction: navigating traumatic brain injury for novel diagnosis and therapy
Considerable strides in medical interventions during the acute phase of traumatic brain injury (TBI) have brought improved overall survival rates....
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Investigating cognitive reserve, symptom resolution and brain connectivity in mild traumatic brain injury
BackgroundA proportion of patients with mild traumatic brain injury (mTBI) suffer long-term consequences, and the reasons behind this are still...
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Unravelling the current shortfalls, challenges, and opportunities in traumatic brain injury
The brain is the control centre of the human body. Injury to the brain can have diverse and disabling effects. Yet there remain important unanswered...
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Mild traumatic brain injury: not always a mild injury
PurposeIn general, risk of mortality after trauma correlates with injury severity. Despite arriving in relatively stable clinical condition, however,...
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Novel biomarkers of preterm brain injury from blood transcriptome in sheep model of intrauterine asphyxia
BackgroundInfants born preterm have a higher incidence of neurological deficits. A key step in finding effective treatments is to identify biomarkers...
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Neuromonitoring in Children with Traumatic Brain Injury
Traumatic brain injury remains a major cause of mortality and morbidity in children across the world. Current management based on international...
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Case identification of non-traumatic brain injury in youth using linked population data
BackgroundPopulation-level administrative data provides a cost-effective means of monitoring health outcomes and service needs of clinical...
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Psychiatric sequelae of traumatic brain injury — future directions in research
Despite growing appreciation that traumatic brain injury (TBI) is an important public health burden, our understanding of the psychiatric and...