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Different pain phenotypes are associated with anti-Caspr2 autoantibodies
Autoantibodies against contactin-associated protein 2 (Caspr2) not only induce limbic autoimmune encephalitis but are also associated with pain...
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Autoantibodies in patients with obsessive-compulsive disorder: a systematic review
Obsessive-compulsive disorder (OCD) is a frequent and debilitating mental illness. Although efficacious treatment options are available, treatment...
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Plasma anti-myosin autoantibodies in the diagnosis of necrotizing enterocolitis
We aimed to assess whether autoantibodies can be used as biomarkers for necrotizing enterocolitis (NEC) and applied for its early diagnosis. A...
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Autoantibodies to ACE2 and immune molecules are associated with COVID-19 disease severity
BackgroundIncreased inflammation caused by SARS-CoV-2 infection can lead to severe coronavirus disease 2019 (COVID-19) and long-term disease...
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The presence and clinical significance of autoantibodies in amyotrophic lateral sclerosis: a narrative review
Amyotrophic lateral sclerosis (ALS) is a debilitating and rapidly fatal neurodegenerative disease, which is characterized by the selective loss of...
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Elevated plasma levels of specific antiplatelet glycoprotein autoantibodies in patients with primary Sjögren syndrome with thrombocytopenia
IntroductionThrombocytopenia is one of the primary Sjögren’s syndrome (pSS) hematological manifestations. The objective of this study was to evaluate...
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Anti-integrin αvβ6 autoantibodies in patients with primary sclerosing cholangitis
BackgroundPatients with primary sclerosing cholangitis (PSC) possess autoantibodies against biliary epithelial cells. However, the target molecules...
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Islet autoantibodies as precision diagnostic tools to characterize heterogeneity in type 1 diabetes: a systematic review
BackgroundIslet autoantibodies form the foundation for type 1 diabetes (T1D) diagnosis and staging, but heterogeneity exists in T1D development and...
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The peculiar features, diversity and impact of citrulline-reactive autoantibodies
Since entering the stage 25 years ago as a highly specific serological biomarker for rheumatoid arthritis, anti-citrullinated protein antibodies...
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The prevalence of positive thyroid autoantibodies in patients with subacute thyroiditis: a systematic review and meta-analysis
Purpose:Subacute thyroiditis (SAT) is a transient inflammatory disorder of the thyroid gland with a possible viral etiology. We conducted this study...
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Repositioning synthetic glucocorticoids in psychiatric disease associated with neural autoantibodies: a narrative review
Synthetic glucocorticoids (sGCs) are a well-investigated and standard drug therapy for disorders associated with CNS inflammation. Less is known...
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Correlation between extraocular muscle enlargement and thyroid autoantibodies in thyroid eye disease
PurposeThis study aimed to investigate the factors affecting extraocular muscle enlargement in thyroid eye disease (TED).
Study design ...
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Higher prevalence of thyroid-specific autoantibodies (TPOAb and TgAb) is related to a higher prevalence of fractures in females: results from NHANES 2007–2010
SummaryA retrospective analysis was conducted using data from the NHANES. Bone mineral density (BMD) was compared in different thyroid-specific...
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Pathogenic autoantibodies in multiple sclerosis — from a simple idea to a complex concept
The role of autoantibodies in multiple sclerosis (MS) has been enigmatic since the first description, many decades ago, of intrathecal immunoglobulin...
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Neuronal autoantibodies in a sample of Egyptian patients with drug-resistant epilepsy
BackgroundEpilepsy is one of the most common and chronic neurological diseases. About one-third of epilepsy patients do not achieve seizure freedom...
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The role of seven tumor-associated autoantibodies in the diagnosis, staging and treatment guidance of lung cancer
BackgroundThis study assessed the diagnosis, staging and treatment guidance of lung cancer (LC) based on seven tumor-associated autoantibodies...
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Multiple intracellular pathogen infections with ocular pathologies associated with adult-onset immunodeficiency due to anti-interferon-γ autoantibodies: a case report
BackgroundAutoantibodies against interferon-γ (IFN-γ) can inhibit IFN-γ-dependent signal transducer and activator of transcription 1 phosphorylation...
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Utility of Myositis-Specific Autoantibodies for Treatment Selection in Myositis
Purpose of ReviewAutoimmune myopathies (IMs) are a group of diseases characterized by muscle weakness and inflammatory infiltrates on the muscle...
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Determination of autoantibodies in type 2 diabetes: one simple way to improve classification
This letter aims to increase interest in better classification of type 2 diabetes. This can be done in a simple and cheap way via determination of...
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Multiple refractory intracellular pathogen infections in a human immunodeficiency virus-negative patient with anti-interferon-γ autoantibodies: a case report
BackgroundThe clinical presentation of adult-onset immunodeficiency with anti-interferon (IFN)-γ autoantibodies with intracellular pathogens can be...
