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Effects of antiviral therapy and drug withdrawal on postpartum hepatitis in pregnant women with chronic HBV infection
ObjectiveTo investigate the effect of antiviral therapy and drug withdrawal on the incidence of hepatitis B after delivery in pregnant women with...
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Mechanisms and Clinical Significance of Pharmacokinetic Drug Interactions Mediated by FDA and EMA-approved Hepatitis C Direct-Acting Antiviral Agents
The treatment of patients infected with the hepatitis C virus (HCV) has been revolutionised by the development of direct-acting antiviral agents...
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Antiviral activity and mechanism of the antifungal drug, anidulafungin, suggesting its potential to promote treatment of viral diseases
BackgroundThe severe fever with thrombocytopenia syndrome disease (SFTS), caused by the novel tick-borne SFTS virus (SFTSV), was listed among the top...
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Perceived Risk for Severe COVID-19 and Oral Antiviral Use Among Antiviral-Eligible US Adults
IntroductionOral antiviral medications are important tools for preventing severe COVID-19 outcomes. However, their uptake remains low for reasons...
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Detection of antiviral drug resistance in patients with congenital cytomegalovirus infection using long-read sequencing: a retrospective observational study
BackgroundCongenital human cytomegalovirus (cCMV) infection can cause sensorineural hearing loss and neurodevelopmental disabilities in children....
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Association between human herpesvirus-6 encephalitis and antiviral prophylaxis after allogeneic hematopoietic stem cell transplantation in the letermovir era
The impact of letermovir (LTV)—an anti-cytomegalovirus (CMV) drug—on human herpesvirus-6 (HHV-6) encephalitis is unclear. We hypothesized that LTV...
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Screening and verification of antiviral compounds against HSV-1 using a method based on a plaque inhibition assay
BackgroundHerpes simplex virus type 1 (HSV-1) infection is a common viral disease that mainly causes oral lesions, but can also cause genital lesions...
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Clinical antiviral efficacy of favipiravir in early COVID-19 (PLATCOV): an open-label, randomised, controlled, adaptive platform trial
Brief summaryIn early symptomatic COVID-19 treatment, high dose oral favipiravir did not accelerate viral clearance.
BackgroundFavipiravir, an...
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Construction of recombinant fluorescent LSDV for high-throughput screening of antiviral drugs
Lumpy skin disease virus (LSDV) infection is a major socio-economic issue that seriously threatens the global cattle-farming industry. Here, a...
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Potential antiviral activities of chrysin against hepatitis B virus
BackgroundInterferon and nucleos(t)ide analogues are current therapeutic treatments for chronic Hepatitis B virus (HBV) infection with the...
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Cytomegalovirus enteritis resistant to antiviral drugs improved following total colectomy
BackgroundCytomegalovirus (CMV) infection, often subclinical in childhood, is reactivated during a state of cell-mediated immunodeficiency. In cases...
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CNS Viral Infections—What to Consider for Improving Drug Treatment: A Plea for Using Mathematical Modeling Approaches
Neurotropic viruses may cause meningitis, myelitis, encephalitis, or meningoencephalitis. These inflammatory conditions of the central nervous system...
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GC–MS and ADME profile analysis of Carcinoscorpius rotundicauda bioactive compounds and their potential as COVID-19 antiviral
BackgroundCarcinoscorpius rotundicauda is a species of horseshoe crab that is rarely studied. This animal is often used as part of the blood as a...
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Chinese herbal extracts with antiviral activity: evaluation, mechanisms, and potential for preventing PRV, PEDV and PRRSV infections
The rapid expansion of large-scale pig farming has brought about a surge in viral diseases with high morbidity rates and diverse manifestations. This...
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Estimation of Intangible Costs for Factors Associated with Oral Antiviral Drugs for COVID-19 Treatment: A Conjoint Analysis in Japan
IntroductionDuring the recent coronavirus disease 2019 (COVID-19) pandemic, preferences for factors associated with vaccines have been evaluated....
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SP2509, a specific antagonist of LSD1, exhibits antiviral properties against Porcine epidemic diarrhea virus
BackgroundPorcine epidemic diarrhea virus (PEDV), a type of coronavirus, is one of the main pathogens that can infect pigs of all ages. It causes...
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Assessing antiviral treatment efficacy and risk factors for severe COVID-19 in kidney transplant recipients during the Omicron subvariant-dominant period: a retrospective study
BackgroundKidney transplant recipients (KTRs) are at risk of severe coronavirus disease 2019 (COVID-19), and even now that Omicron subvariants have...
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Comparison between available early antiviral treatments in outpatients with SARS-CoV-2 infection: a real-life study
PurposeTo investigate the clinical impact of three available antivirals for early COVID-19 treatment in a large real-life cohort.
Methods ...
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Effect of prophylactic antiviral intervention on T cell immunity in hepatitis B virus-infected pregnant women
BackgroundAntiviral intervention in hepatitis B virus (HBV)-infected pregnant women can effectively reduce mother-to-child transmission. However, the...
