Search

Search Results

1. Amino acid metabolism in health and disease

   Amino acids are the building blocks of protein synthesis. They are structural elements and energy sources of cells necessary for normal cell growth,...

   Zhe-Nan Ling, Yi-Fan Jiang, ... Jian Wu in Signal Transduction and Targeted Therapy

   Article Open access 13 September 2023
   

2. Amino Acid Metabolism in Bone Metastatic Disease

   Purpose of Review

   Breast and prostate tumors frequently metastasize to the bone, but the underlying mechanisms for osteotropism remain elusive. An...

   Deanna N. Edwards in Current Osteoporosis Reports

   Article 06 June 2023
   

3. Possible-sarcopenic screening with disturbed plasma amino acid profile in the elderly

   Background

   The mass and strength of skeletal muscle decline with age, leading to its progressive dysfunction. High-throughput metabolite profiling...

   Yushuang Duan, Kuan Tao, ... Yifan Lu in BMC Geriatrics

   Article Open access 12 July 2023
   

4. L-2hydroxyglutaric acid rewires amino acid metabolism in colorectal cancer via the mTOR-ATF4 axis

   Oncometabolites, such as D/L-2-hydroxyglutarate (2HG), have directly been implicated in carcinogenesis; however, the underlying molecular mechanisms...

   Sho Tabata, Yasushi Kojima, ... Tomoyoshi Soga in Oncogene

   Article Open access 06 March 2023
   

5. The correlation between serum total bile acid and alanine aminotransferase of pregnant women and the disorders of neonatal hyperbilirubinemia-related amino acid metabolism

   Background

   To explore the association between liver metabolism-related indicators in maternal serum and neonatal hyperbilirubinemia (NHB), and further...

   **zhenzi Fan, Huijuan Rong, ... Tianxiao Yu in BMC Pregnancy and Childbirth

   Article Open access 03 January 2024

6. Prognostic value of amino acid metabolism-related gene expression in invasive breast carcinoma

   Background

   An increasing number of studies indicated that metabolic reprogramming of amino acid metabolism may either promote or inhibit tumor...

   Zilin Wang, **nyu Guo, ... Kangan Li in Journal of Cancer Research and Clinical Oncology

   Article 21 June 2023
   

7. Dietary Methionine and Total Sulfur Amino Acid Restriction in Healthy Adults

   Objectives

   Dietary restriction of methionine (Met) and cysteine (Cys) delays the aging process and aging-related diseases, improves glucose and fat...

   John P. Richie Jr., Raghu Sinha, ... D. Orentreich in The journal of nutrition, health & aging

   Article 23 January 2023
   

8. Amino acid availability enhanced through glucose coadministration of amino acid supplementation during hemodiafiltration: two case reports

   Background

   Intravenous administration of amino acid (AA) formulation (IVAA) as intradialytic parenteral nutrition is widely used for malnourished...

   Masako Fujiwara, Itiro Ando, ... Hiroyuki Terawaki in Renal Replacement Therapy

   Article Open access 25 June 2022
   

9. Guanidine acetic acid supplementation altered plasma and tissue free amino acid profiles in finishing pigs

   Background

   As a nutritive feed additive, guanidine acetic acid (GAA) participates in the metabolism of energy and proteins. This study aimed to...

   Yiyan Cui, Zhimei Tian, ... Limin Wang in Porcine Health Management

   Article Open access 07 June 2022
   

10. Amino acid metabolism in immune cells: essential regulators of the effector functions, and promising opportunities to enhance cancer immunotherapy

    Amino acids are basic nutrients for immune cells during organ development, tissue homeostasis, and the immune response. Regarding metabolic...

    Luming Yang, Zhaole Chu, ... Bin Wang in Journal of Hematology & Oncology

    Article Open access 05 June 2023
    

11. Mothers’ lived experience of caring for children with inborn errors of amino acid metabolism

    Background

    Inborn errors of amino acid metabolism are chronic conditions that have many sequels. Mothers of these children are facing different...

    Sara Shirdelzade, Monir Ramezani, ... Abbas Heydari in BMC Pediatrics

    Article Open access 07 June 2023

12. Dietary amino acid intake and sleep duration are additively involved in future cognitive decline in Japanese adults aged 60 years or over: a community-based longitudinal study

    Background

    Sleep duration and amino acid intake are independently associated with cognitive decline. This study aimed to determine the longitudinal...

    Kaori Kinoshita, Rei Otsuka, ... Hidenori Arai in BMC Geriatrics

    Article Open access 11 October 2023

13. Effect of an enteral amino acid blend on muscle and gut functionality in critically ill patients: a proof-of-concept randomized controlled trial

    Background

    A defining feature of prolonged critical illness is muscle wasting, leading to impaired recovery. Supplementation with a tailored blend of...

    Nicholas Heming, Robert Carlier, ... Djillali Annane in Critical Care

    Article Open access 17 November 2022
    

14. Effects of amino acid supplementation on muscle mass, muscle performance and functional capacity in subjects undergoing total knee arthroplasty: a systematic review of randomized clinical trials

    The aim of the present study was to summarize the effectiveness of amino acid supplementation on muscle strength, muscle volume, and functional...

    Jose Humberto de Souza Borges, Paulo Lobo Junior, ... Fabrício Reichert Barin in European Journal of Orthopaedic Surgery & Traumatology

    Article 18 January 2024
    

15. N-thiocarboxyanhydrides, amino acid-derived enzyme-activated H₂S donors, enhance sperm mitochondrial activity in presence and absence of oxidative stress

    Background

    Hydrogen sulfide (H ₂ S) donors are crucial tools not only for understanding the role of H ₂ S in cellular function but also as promising...

    Eliana Pintus, Abigail F. Chinn, ... José Luis Ros-Santaella in BMC Veterinary Research

    Article Open access 16 February 2023
    

16. HA gene amino acid mutations contribute to antigenic variation and immune escape of H9N2 influenza virus

    Based on differences in the amino acid sequence of the protein haemagglutinin (HA), the H9N2 avian influenza virus (H9N2 virus) has been clustered...

    Rui Zhu, Shunshun Xu, ... **ufan Liu in Veterinary Research

    Article Open access 15 June 2022
    

17. A position statement on the post gene-therapy rehabilitation of aromatic I-amino acid decarboxylase deficiency patients

    Aromatic l -amino acid decarboxylase (AADC) deficiency is a rare genetic disorder of monoamine neurotransmitter synthesis that presents with a range...

    Hui-Min Lee, Saadet Mercimek-Andrews, ... Wuh-Liang Hwu in Orphanet Journal of Rare Diseases

    Article Open access 18 January 2024
    

18. The effect of continuous venovenous hemodiafiltration on amino acid delivery, clearance, and removal in children

    Background

    In critically ill children with acute kidney injury (AKI), continuous kidney replacement therapy (CKRT) enables nutrition provision. The...

    Richard P Lion, Molly R Vega, ... Ayse Akcan Arikan in Pediatric Nephrology

    Article 12 August 2021
    

19. Cationic amino acid transporter-1 (CAT-1) promotes fibroblast-like synoviocyte proliferation and cytokine secretion by taking up L-arginine in rheumatoid arthritis

    Background

    Abnormal proliferation of fibroblast-like synoviocytes (FLSs) in the synovial lining layer is the primary cause of synovial hyperplasia and...

    Ying Lu, Chongbo Hao, ... Lieying Fan in Arthritis Research & Therapy

    Article Open access 17 October 2022
    

20. Serum Amino Acid Profile Changes After Repetitive Breath-Hold Dives: A Preliminary Study

    Background

    The aim of this work was to investigate the serum amino acid (AA) changes after a breath-hold diving (BH-diving) training session under...

    Danilo Cialoni, Andrea Brizzolari, ... Alessandra Barassi in Sports Medicine - Open

    Article Open access 20 June 2022