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Macular lesions associated with age-related macular degeneration in pachydrusen eyes
BackgroundTo investigate the prevalence of macular lesions associated with age-related macular degeneration (AMD) in eyes with pachydrusen.
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Volume-rendering three-dimensional image analysis of macular neovascularization in age-related macular degeneration
BackgroundTo visualize and investigate the three-dimensional (3D) images of macular neovascularization (MNV) in eyes with neovascular age-related...
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Serum adropin level in wet-type age-related macular degeneration
PurposeOur objective was to compare the serum Adropin levels between patients with wet-type Age-Related Macular Degeneration (AMD) and otherwise...
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Diurnal variation of optical coherence tomography–based macular fluid in exudative age-related macular degeneration
BackgroundSignificant diurnal fluctuation of optical coherence tomography (OCT)-based macular fluid occurs in patients with several macular...
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Tyrosine Kinase Inhibitors and their role in treating neovascular age-related macular degeneration and diabetic macular oedema
The advent of intravitreal anti-VEGF injections has revolutionised the treatment of both neovascular age-related macular degeneration (nAMD or wet...
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Mast cells in human choroid and their role in age-related macular degeneration (AMD)
The role of mast cells in physiologic and pathological processes extends far beyond the allergy processes: they are involved in wound healing,...
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Optical Coherence Tomography Angiography: A 2023 Focused Update on Age-Related Macular Degeneration
Optical coherence tomography angiography (OCTA) has extensively enhanced our comprehension of eye microcirculation and of its associated diseases. In...
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Anti-VEGF Drugs in Age-Related Macular Degeneration: A Focus on Dosing Regimen-Related Safety and Efficacy
Age-related macular degeneration (AMD) is one of the main causes of visual impairment and severe visual loss, and can progress to two advanced...
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Shedding Light on Photobiomodulation Therapy for Age-Related Macular Degeneration: A Narrative Review
BackgroundPhotobiomodulation (PBM) relies on the pathophysiological mechanism whereby red to near-infrared light can target mitochondrial activity...
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Quantitative response of macular neovascularisation to loading phase of aflibercept in neovascular age-related macular degeneration
PurposeTo evaluate quantitative morphological changes in macular neovascularisation (MNV) network after aflibercept therapy in neovascular...
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Advancements in Imaging and Therapeutic Options for Dry Age-Related Macular Degeneration and Geographic Atrophy
Age-related macular degeneration (AMD) is a leading cause of vision loss in the elderly, with dry AMD (d-AMD) leading to geographic atrophy (GA) and...
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AI-based support for optical coherence tomography in age-related macular degeneration
Artificial intelligence (AI) has emerged as a transformative technology across various fields, and its applications in the medical domain,...
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Association of NLRPs with pathogenesis of dry age-related macular degeneration
BackgroundAge-related macular degeneration (AMD) is the leading cause of blindness in the elderly population, and Dry AMD is the most common clinical...
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Faricimab for neovascular age-related macular degeneration and diabetic macular edema: from preclinical studies to phase 3 outcomes
Intravitreal anti–vascular endothelial growth factor (VEGF) therapy is the standard of care for diabetic macular edema (DME) and neovascular...
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Association between ambient air pollution and age-related macular degeneration: a meta-analysis
BackgroundSeveral epidemiological studies have investigated the association between ambient air pollution and age-related macular degeneration (AMD)....
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Qualitative and quantitative comparisons of type 1 macular neovascularizations between pachychoroid neovasculopathy and neovascular age-related macular degeneration using optical coherence tomography angiography
ObjectivesTo compare qualitative and quantitative features of type 1 macular neovascularizations (MNV) in pachychoroid neovasculopathy (PNV) and...
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Biomarkers for the Progression of Intermediate Age-Related Macular Degeneration
Age-related macular degeneration (AMD) is a leading cause of severe vision loss worldwide, with a global prevalence that is predicted to...
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Short-term outcomes of intravitreal faricimab for refractory neovascular age-related macular degeneration
PurposeTo assess the short-term outcomes of intravitreal faricimab (IVF) for previously treated refractory neovascular age-related macular...
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Subclinical Angioid Streaks with Pseudodrusen: A New Phenotype of Age-Related Macular Degeneration
IntroductionTo describe subclinical angioid streaks (AS) as a frequent, peculiar age-related macular degeneration (AMD) phenotype, comparing features...
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Diagnostic accuracy of self-reported age-related macular degeneration in the ASPREE Longitudinal Study of Older Persons
BackgroundThe validity of findings from epidemiological studies using self-report of ophthalmic conditions depends on several factors. We assessed...