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Considering Adverse Effects of Common Antihypertensive Medications in the ED
Purpose of ReviewTo evaluate the adverse effects of common antihypertensive agents utilized or encountered in the Emergency Department.
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Evaluating Monitoring Guidelines of Clozapine-Induced Adverse Effects: a Systematic Review
Background and ObjectivesDespite the evidence that no other antipsychotic is effective as clozapine for the treatment of resistant schizophrenia, it...
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Progress in the clinical effects and adverse reactions of ticagrelor
BackgroundTicagrelor is a novel receptor antagonist that selectively binds to the P2Y12 receptor, thereby inhibiting adenosine diphosphate...
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Sex Differences in Adverse Effects of Antiseizure Medications in Adults with Epilepsy: A Systematic Review
BackgroundSex differences in epilepsy have been described in prevalence, seizure propensity and response to treatment. Therefore, taking into account...
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Sex differences in autonomic adverse effects related to antipsychotic treatment and associated hormone profiles
Autonomic adverse effects of antipsychotic drugs (APs) cause clinical challenges, but few studies have investigated sex differences and their...
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Tamoxifen Dose De-Escalation: An Effective Strategy for Reducing Adverse Effects?
Tamoxifen, a cornerstone in the adjuvant treatment of estrogen receptor-positive breast cancer, significantly reduces breast cancer recurrence and...
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Seeking adverse effects in systematic reviews of orthodontic interventions: a cross-sectional study (part 1)
BackgroundSystematic reviews that assess the benefits of interventions often do not completely capture all dimensions of the adverse effects. This...
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Beliefs and counseling practices among dermatologists regarding sexual and other adverse effects of finasteride
Finasteride may cause low libido and erectile dysfunction and the product label of finasteride also includes post-marketing reactions of sexual...
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High circulating MIF levels indicate the association with atypical antipsychotic-induced adverse metabolic effects
Atypical antipsychotics (AAPs) are primary medications for schizophrenia (SZ). However, their use is frequently associated with the development of...
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Adverse effects associated with acupuncture therapies: An evidence map** from 535 systematic reviews
Background and ObjectiveConsidering that physicians and patients widely use acupuncture, it is necessary to explore its adverse effects during...
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Adverse effects of tyrosine kinase inhibitors in cancer therapy: pathophysiology, mechanisms and clinical management
Since their invention in the early 2000s, tyrosine kinase inhibitors (TKIs) have gained prominence as the most effective pathway-directed anti-cancer...
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Optimizing glucocorticoid therapy for Behçet's uveitis: efficacy, adverse effects, and advances in combination approaches
Behçet's uveitis (BU) is a debilitating manifestation of Behçet's disease, often requiring prompt and aggressive treatment to prevent vision loss....
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Endocrine Therapy for Surgeons: Practical Pearls for Managing Menopausal, Bone Loss and Sexual Adverse Effects
Breast cancer patients are living longer than ever before and as such the population of breast cancer survivors continues to grow. Approximately 80%...
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Advanced statistics identification of participant and treatment predictors associated with severe adverse effects induced by fluoropyrimidine-based chemotherapy
PurposeAdverse effects following fluoropyrimidine-based chemotherapy regimens are common. However, there are no current accepted diagnostic markers...
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Dental Adverse Effects of Anti-CD20 Therapies
IntroductionOver the past few years, anti-CD20 therapies like rituximab, ocrelizumab or ofatumumab have seen an increase in interest in the treatment...
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Managing Adverse Effects of Novel Therapeutic Agents in Gynecologic Malignancies
Gynecologic cancer treatments have evolved significantly. Several targeted therapies are approved for use in combination with cytotoxic therapy, as...
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Adverse effects following COVID-19 vaccination in Iran
BackgroundVaccination is a key intervention to prevent COVID-19. Many vaccines are administered globally, yet there is not much evidence regarding...
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Spin on adverse effects in abstracts of systematic reviews of orthodontic interventions: a cross-sectional study (part 2)
BackgroundIt is critical that abstracts of systematic reviews transparently report both the beneficial and adverse effects of interventions without...
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The effects of mesenchymal stromal cells and platelet-rich plasma treatments on cutaneous wound healing: ignoring the possibility of adverse events and side effects could compromise study results
Common medical events may be associated with decreased immunologic activity and dysregulation of functional epithelial and neuronal tissues caused by...
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Chemotherapy: how to reduce its adverse effects while maintaining the potency?
Chemotherapy is one of the widely used anticancer treatments that involves the use of powerful cytotoxic drugs to stop tumor growth by targeting...
