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  1. Iatrogenic adrenal insufficiency in adults

    Iatrogenic adrenal insufficiency (IAI) is the most common form of adrenal insufficiency in adult patients, although its overall exact prevalence...

    Julie Martin-Grace, Maria Tomkins, ... Mark Sherlock in Nature Reviews Endocrinology
    Article 25 January 2024
  2. Rare forms of genetic paediatric adrenal insufficiency: Excluding congenital adrenal hyperplasia

    Adrenal insufficiency (AI) is a severe endocrine disorder characterized by insufficient glucocorticoid (GC) and/or mineralocorticoid (MC) secretion...

    Valeria Hasenmajer, Rosario Ferrigno, ... Martin O. Savage in Reviews in Endocrine and Metabolic Disorders
    Article Open access 10 February 2023
  3. Adrenal insufficiency in liver diseases - pathophysiology and underlying mechanisms

    Relative adrenal insufficiency (RAI) is common in critically ill patients with cirrhosis, but it has been also documented in non-critically ill...

    Maria Kalafateli, Ioanna Aggeletopoulou, Christos Triantos in Reviews in Endocrine and Metabolic Disorders
    Article 02 February 2024
  4. SCARB1 downregulation in adrenal insufficiency with Allgrove syndrome

    Background

    Allgrove disease is a rare genetic syndrome characterized by adrenal insufficiency, alacrimia, achalasia and complex neurological...

    Giacomo Bitetto, Gianluca Lopez, ... Alessio Di Fonzo in Orphanet Journal of Rare Diseases
    Article Open access 19 June 2023
  5. Primary adrenal insufficiency due to bilateral adrenal hemorrhage-adrenal infarction in a patient with systemic lupus erythematosus and antiphospholipid syndrome: case presentation and review of the literature

    Primary adrenal insufficiency (PAI) is a rare disease which represents the end stage of a destructive process involving the adrenal cortex....

    K. Bouki, V. Venetsanaki, ... Paraskevi Xekouki in Hormones
    Article Open access 12 July 2023
  6. Adrenal insufficiency after curative-intent gastric cancer treatment: a case report

    Background

    Adrenal insufficiency is a life-threatening condition, and advanced gastric cancer is associated with very poor prognosis. Adrenalectomy...

    Johan Hardvik Åkerström, Cecilia Radkiewicz in Journal of Medical Case Reports
    Article Open access 11 April 2023
  7. Bilateral adrenal infarction and insufficiency associated with antiphospholipid syndrome and surgery: a case report

    Background

    Antiphospholipid syndrome causes systemic arterial and venous thromboses due to the presence of antiphospholipid antibodies. Adrenal...

    Yoshihito Iijima, Masahito Ishikawa, ... Hidetaka Uramoto in International Journal of Emergency Medicine
    Article Open access 21 December 2023
  8. Infections and gender: clues for diagnosis of adrenal insufficiency—a case report and a review of the literature

    The clinical presentation of adrenal insufficiency, a condition causing adrenal hormone deficiency, is characterised by non-specific symptoms and...

    Giacomo Grandi, Michele Di Stefano, ... Antonio Di Sabatino in Internal and Emergency Medicine
    Article Open access 18 June 2024
  9. Autoimmune adrenal insufficiency in children: a hint for polyglandular syndrome type 2?

    Background

    Primary adrenal insufficiency (PAI) in childhood is a life-threatening disease most commonly due to impaired steroidogenesis. Differently...

    Marta Arrigoni, Paolo Cavarzere, ... Franco Antoniazzi in Italian Journal of Pediatrics
    Article Open access 29 July 2023
  10. Hyponatremia due to adrenal insufficiency after a Mamushi bite: a case report

    Background

    Mamushi bites are the most common venomous snake bites in Japan, with known complications including rhabdomyolysis and acute kidney...

    Ryu Sugimoto, Tsuneaki Kenzaka, Hogara Nishisaki in BMC Endocrine Disorders
    Article Open access 11 October 2023
  11. Basal cortisol in relation to metyrapone confirmation in predicting adrenal insufficiency after pituitary surgery

    Purpose

    Pituitary surgery can lead to post-surgical adrenal insufficiency with the need for glucocorticoid replacement and significant disease related...

    Pieter E. Huisman, Sarah E. Siegelaar, ... Eveline Bruinstroop in Pituitary
    Article Open access 19 January 2024
  12. Adrenal insufficiency management in the pediatric emergency setting and risk factors for adrenal crisis development

    Background

    In patients with adrenal insufficiency (AI), adrenal crisis (AC) represents a clinical emergency. Early recognition and prompt management...

    Enrica Abrigo, Jessica Munarin, ... Patrizia Matarazzo in Italian Journal of Pediatrics
    Article Open access 06 June 2023
  13. Clinical insights of pregnancy management, adrenal insufficiency as a possible cause of elevated TSH: a pilot study of case series

    Background

    The upper limit for thyroid-stimulating hormone has been strictly defined for pregnancy management, at which point levothyroxine...

    Ken Kanazawa, Tatsuro Inaba, ... Koichiro Kuwabara in BMC Pregnancy and Childbirth
    Article Open access 04 October 2023
  14. A schedule for tapering glucocorticoid treatment in patients with severe SARS-CoV 2 infection can prevent acute adrenal insufficiency in the geriatric population

    Objective and design

    Glucocorticoids (GCs) have been widely used in symptomatic patients for the treatment of COVID-19. The risk for adrenal...

    Irene Tizianel, Elena Ruggiero, ... Filippo Ceccato in Hormones
    Article Open access 17 May 2024
  15. Primary adrenal insufficiency and myocarditis in COVID-19 disease: a case report

    Background

    COVID-19 has different manifestations from respiratory to GI problems, and some of them are more common, but some are rare. Reporting rare...

    Delaram Eskandari, Amir Ziaee, ... Atefe Tirkan in BMC Endocrine Disorders
    Article Open access 31 December 2022
  16. Predicting iatrogenic adrenal insufficiency in neonates exposed to prolonged steroid courses: do cortisol levels help?

    Objective

    To determine whether random cortisol levels obtained in neonates to assess for secondary adrenal insufficiency (AI) after prolonged steroid...

    Kristen Rosano, Saya Bery, ... Rita M. Ryan in Journal of Perinatology
    Article Open access 20 May 2024
  17. Dual-release hydrocortisone improves body composition and the glucometabolic profile in patients with secondary adrenal insufficiency

    Purpose

    Studies have suggested improved metabolic profiles in patients with adrenal insufficiency treated with dual-release hydrocortisone (DR-HC)...

    Nanna Thurmann Jørgensen, Victor Brun Boesen, ... Marianne Klose in Endocrine
    Article Open access 12 February 2024
  18. An unusual cause of adrenal insufficiency with elevation of 17-hydroxyprogesterone: case report

    Background

    We present an intriguing case of primary adrenal lymphoma, with associated primary adrenal insufficiency (PAI), in a patient presenting a...

    Claudia Teti, Giampaolo Bezante, ... Mara Boschetti in BMC Endocrine Disorders
    Article Open access 29 May 2023
  19. Symptoms and steroid dose adjustments following the Covid-19 vaccine in patients with adrenal insufficiency

    Background

    A proportion of patients with adrenal insufficiency (AI) require increases in their maintenance glucocorticoids following the Covid-19...

    David S. McLaren, Grace Crowe, ... Robert D. Murray in Pituitary
    Article 17 November 2023
  20. Primary adrenal insufficiency developed 22 years after the diagnosis of light and heavy chain deposition disease: a case report

    Monoclonal immunoglobulin deposition diseases (MIDDs), including light and heavy chain deposition disease (LHCDD), are rare and heterogeneous...

    Eriko Eguchi in CEN Case Reports
    Article 20 May 2024
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