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Long-term outcomes of high-dose-rate brachytherapy and external beam radiotherapy without hormone therapy for high-risk localized prostate cancer
PurposeUntil March 2018, patients with high-risk localized prostate cancer had been administered high-dose-rate brachytherapy (HDR-BT) combined with...
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Effects of Hormone Replacement Therapy on Women's Lung Health and Disease
This review provides an overview of menopausal hormone therapy and pulmonary disease risk, with a focus on the effect of hormone replacement therapy...
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Pelvic Floor Dysfunction in Transgender Men on Gender-affirming Hormone Therapy: A Descriptive Cross-sectional Study
Introduction and HypothesisThe objective of this research is to explore the effects of hormone therapy using testosterone on pelvic floor dysfunction...
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Long-term breast cancer incidence trends by mammography, obesity, and menopausal hormone therapy
PurposeOver the past half century, the annual age-adjusted breast cancer incidence in the USA has fluctuated, potentially influenced by changes in...
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Impact of medical therapy for hormone-secreting Pituitary tumors on bone
PurposeBone health is often impaired in patients with hormone-secreting pituitary tumors. Since medical therapy is central to their care,...
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Menopausal hormone therapy reduces the risk of fracture regardless of falls risk or baseline FRAX probability—results from the Women’s Health Initiative hormone therapy trials
SummaryIn a combined analysis of 25,389 postmenopausal women aged 50–79 years, enrolled in the two Women’s Health Initiative hormone therapy trials,...
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Postmenopausal Osteoporosis: Menopause Hormone Therapy and Selective Estrogen Receptor Modulators
IntroductionOsteoporosis is a debilitating silent disease with a huge socio-economic impact. Prevention strategies and early detection of...
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Menopausal Hormone Therapy in Older Women: Examining the Current Balance of Evidence
Menopause occurs in all women. During the menopause transition, 80% of women experience vasomotor symptoms that can last an average of 7–10 years or...
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Differentiated thyroid cancer: a focus on post-operative thyroid hormone replacement and thyrotropin suppression therapy
PurposeThis review focuses on post-operative thyroid hormone replacement and thyrotropin suppression therapy in patients with differentiated thyroid...
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The effect of hormone therapy on physiological uptake of the endometrium on [18F]F-FDG PET in postmenopausal women
ObjectiveThe effects of hormonal therapy, estrogen-based hormone replacement therapy (HRT), and anti-tumor hormone therapy, such as tamoxifen, on the...
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Persistent vaginal bleeding during gender-affirming hormone therapy in transgender men
PurposeWhile it is common for menstrual cycles to cease within the initial 6 months of treatment, there are instances where some transgender men may...
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Genomic Testing to Guide Local Therapy Decisions in Hormone Receptor-Positive Breast Cancer
Purpose of ReviewTo explore how genomic testing has changed local therapy decision-making, specifically surgical timing and opportunities for...
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Menopausal Hormone Therapy in Women with Type 2 Diabetes Mellitus: An Updated Review
Menopause is accompanied by several metabolic adaptations, which are related to insulin resistance, increased total body fat mass, and central...
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The outcomes of growth hormone therapy in the obstructive sleep apnea parameters of Prader–Willi syndrome patients: a systematic review
PurposePrader–Willi syndrome is a serious genetic condition, capable of causing endocrinological imbalance, which has as one of its main treatments...
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Metastatic Hormone–Sensitive Prostate Cancer in the Era of Doublet and Triplet Therapy
Treatment for metastatic hormone–sensitive prostate cancer has undergone significant evolution in recent years, leading to substantial improvements...
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Vaginal Hormone Therapy for Conditions of the Lower Urinary Tract
Purpose of ReviewUp to half of postmenopausal women experience genitourinary symptoms secondary to hormone deficiency, and there is little consensus...
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Evidence and emerging trends in local therapy for metastatic hormone-sensitive prostate cancer: a narrative review
IntroductionMetastatic hormone-sensitive prostate cancer (mHSPC) displays both simultaneous and sequential patterns of metastasis, emphasizing...
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Growth hormone increase by luteinizing hormone-releasing hormone reflects gonadotroph-related characteristics in acromegaly
PurposeWe previously showed the clinical characteristics of acromegaly with a paradoxical growth hormone (GH) response to oral glucose or...
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A Non-Inferiority Study on Endometrial Preparation Prior to FET-Letrozole Versus Hormone Replacement Therapy
BackgroundTo compare the efficacy of letrozole-stimulated cycles to the more conventional artificial programmed cycles, in endometrial preparation...
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Combined pituitary hormone deficiency harboring CHD7 gene missense mutation without CHARGE syndrome: a case report
BackgroundHeterozygous loss-of-function mutations in the chromodomain helicase DNA-binding protein 7 ( CHD7 ) gene cause CHARGE syndrome characterized...
