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Pharmacological Treatment of GHB Withdrawal Syndrome
Purpose of ReviewGamma-hydroxybutyrate (GHB) is an illicit drug used for many reasons: during music festivals or parties, for self-management of...
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Cannabinoid hyperemesis syndrome and cannabis withdrawal syndrome: a review of the management of cannabis-related syndrome in the emergency department
BackgroundCannabis-related medical consultations are increasing worldwide, a non-negligible public health issue; patients presenting to acute care...
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Withdrawal Syndrome Following Discontinuation of 28 Antidepressants: Pharmacovigilance Analysis of 31,688 Reports from the WHO Spontaneous Reporting Database
IntroductionEvidence is lacking on withdrawal syndrome related to individual antidepressants and relevant risk factors for severe reactions.
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Characteristics and outcomes of neonatal opioid withdrawal syndrome in preterm infants: a retrospective cohort study in the current era
ObjectiveCompare Neonatal Opioid Withdrawal Syndrome (NOWS) in preterm and term infants.
Study designSingle center, retrospective chart review of...
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Accuracy of diagnostic codes for prenatal opioid exposure and neonatal opioid withdrawal syndrome
ObjectiveDetermine the accuracy of diagnostic codes in identifying Prenatal Opioid Exposure (POE) and Neonatal Opioid Withdrawal Syndrome (NOWS).
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Implicit Racial Bias in Evaluation of Neonatal Opioid Withdrawal Syndrome
ObjectiveTo assess implicit bias by administrating the Modified Finnegan Score (MFS) for quantifying neonatal opioid withdrawal and to evaluate risk...
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ANK3 rs10994336 and ZNF804A rs7597593 polymorphisms: genetic interaction for emotional and behavioral symptoms of alcohol withdrawal syndrome
ObjectiveAlcohol withdrawal syndrome (AWS) is a complex condition associated with alcohol use disorder (AUD), characterized by significant variations...
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An epidemiological examination of neonatal opioid withdrawal syndrome and maternal and infant characteristics
PurposeAnalyze maternal and infant characteristics by Neonatal Opioid Withdrawal Syndrome (NOWS) status and examine the association between mothers...
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Modulation of intestinal TLR4 expression in infants with neonatal opioid withdrawal syndrome
ObjectiveNeonatal Opioid Withdrawal Syndrome (NOWS) has been associated with the development of necrotizing enterocolitis (NEC) in term and...
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Glucocorticoid Withdrawal Syndrome following treatment of endogenous Cushing Syndrome
Purpose:Literature regarding endogenous Cushing syndrome (CS) largely focuses on the challenges of diagnosis, subty**, and treatment. The enigmatic...
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Addressing drivers of healthcare utilization for neonatal opioid withdrawal syndrome
ObjectiveAim to reduce healthcare utilization (HU) for infants at risk of neonatal opioid withdrawal syndrome (NOWS) by 30% in 1 year and sustain for...
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Pragmatic, randomized, blinded trial to shorten pharmacologic treatment of newborns with neonatal opioid withdrawal syndrome (NOWS)
BackgroundThe incidence of maternal opioid use in the USA has increased substantially since 2000. As a consequence of opioid use during pregnancy,...
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Levoketoconazole in the treatment of patients with endogenous Cushing’s syndrome: a double-blind, placebo-controlled, randomized withdrawal study (LOGICS)
PurposeThe efficacy of levoketoconazole for endogenous Cushing’s syndrome was demonstrated in a phase 3, open-label study (SONICS). This study...
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Morphine versus methadone for neonatal opioid withdrawal syndrome: a randomized controlled pilot study
BackgroundNeonatal Opioid Withdrawal Syndrome (NOWS) is a significant public health issue and while millions of neonates are affected each year, an...
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Abstinence scoring algorithms for treatment of neonatal opioid withdrawal syndrome (NOWS)
ObjectiveChervoneva et al. (2020) developed an abbreviated score (sMNAS-9) derived from full modified Finnegan MOTHER NAS scale (MNAS) for evaluating...
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Opioid, sedative, preadmission medication and iatrogenic withdrawal risk in UK adult critically ill patients: a point prevalence study
BackgroundIatrogenic withdrawal syndrome, after exposure medication known to cause withdrawal is recognised, yet under described in adult intensive...
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Evaluating a web-based training curriculum for disseminating best practices for the care of newborns with neonatal opioid withdrawal syndrome in a rural hospital, the NOWS-NM Program
BackgroundThe incidence of neonatal opiate withdrawal syndrome (NOWS) in the US has grown dramatically over the past two decades. Many rural...
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The Influence of Mediators on the Relationship Between Antenatal Opioid Agonist Exposure and the Severity of Neonatal Opioid Withdrawal Syndrome
Objectives(1) To evaluate the direct (un-mediated) and indirect (mediated) relationship between antenatal exposure to opioid agonist medication as...
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Short term outcomes of neonatal opioid withdrawal syndrome: a comparison of two approaches
ObjectiveTo evaluate outcomes in opioid exposed neonates (OENs) assessed by the Eat, Sleep, Console (ESC) tool compared to the Finnegan Neonatal...
