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Replacing the Clinical Institute Withdrawal Assessment—Alcohol revised with the modified Richmond Agitation and Sedation Scale for alcohol withdrawal to support management of alcohol withdrawal symptoms: potential impact on length of stay and complications
PurposeWe evaluated impact on length of stay and possible complications of replacing the Clinical Institute Withdrawal Assessment—Alcohol Revised...
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Pharmacological Treatment of GHB Withdrawal Syndrome
Purpose of ReviewGamma-hydroxybutyrate (GHB) is an illicit drug used for many reasons: during music festivals or parties, for self-management of...
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Inpatient opioid withdrawal: a qualitative study of the patient perspective
Opioid withdrawal is common among hospitalized patients. Those with substance use disorders exhibit higher rates of patient-directed discharge. The...
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Inhibition of dorsal raphe GABAergic neurons blocks hyperalgesia during heroin withdrawal
Opioid withdrawal signs, such as hyperalgesia, are manifestations of opioid use disorder that may contribute to opioid seeking and taking. We have...
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Video-EEG-monitoring to guide antiseizure medication withdrawal
BackgroundDiscontinuing anti-seizure medication (ASM) should be considered in persons with epilepsy with long-term seizure freedom. Clinicians should...
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Withdrawal during outpatient low dose buprenorphine initiation in people who use fentanyl: a retrospective cohort study
BackgroundBuprenorphine is an effective treatment for opioid use disorder (OUD); however, buprenorphine initiation can be complicated by withdrawal...
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Dialysis withdrawal and symptoms of anxiety and depression: a prospective cohort study
BackgroundAn important aspect of end-of-life decisions in dialysis patients is elective withdrawal from dialysis therapy. Several studies have shown...
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Different projection neurons of basolateral amygdala participate in the retrieval of morphine withdrawal memory with diverse molecular pathways
Context-induced retrieval of drug withdrawal memory is one of the important reasons for drug relapses. Previous studies have shown that different...
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Menstrual migraine is caused by estrogen withdrawal: revisiting the evidence
ObjectiveTo explore and critically appraise the evidence supporting the role of estrogen withdrawal in menstrual migraine.
Main bodyMenstrual...
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Kidney histopathology in predicting flares following drug withdrawal in proliferative lupus nephritis in clinical remission
Residual renal histopathological activity at clinical remission in Proliferative Lupus Nephritis (PLN) can predict renal flare upon immunosuppression...
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Prazosin Enhances the Effectiveness of Mirtazapine on Anxiety- and Depression-Like Behaviors in Rats during Cocaine Withdrawal
Anxiety and depression, key symptoms of the cocaine withdrawal syndrome in human addicts, are considered the main factors that precipitate relapse in...
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Estimating Risk of Antidepressant Withdrawal from a Review of Published Data
Adaptation of the brain to the presence of a drug predicts withdrawal on cessation. The outcome of adaptation is often referred to as ‘physical...
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Brain-derived neurotrophic factor serum levels as a candidate biomarker for withdrawal in crack heroin dependence
BackgroundCrack heroin is a novel opiate derivative with highly addictive properties and unfamiliar health consequences. It causes a variety of brain...
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Insular cortex subregions have distinct roles in cued heroin seeking after extinction learning and prolonged withdrawal in rats
Evidence indicates that the anterior (aIC), but not posterior (pIC), insular cortex promotes cued reinstatement of cocaine seeking after extinction...
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Social withdrawal behaviour in Nepalese infants and the relationship with future neurodevelopment; a longitudinal cohort study
BackgroundSocial withdrawal in infants may be a signal of distress and a precursor for non-optimal development.
ObjectiveTo examine the relationship...
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An acute phase reaction from zoledronate mimicking symptoms seen in opioid withdrawal: a case report
BackgroundZoledronate, a bisphosphonate, is a potent first-line treatment for osteoporosis. It is also a preferred treatment for hypercalcemia...
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Unravelling complex choices: multi-stakeholder perceptions on dialysis withdrawal and end-of-life care in kidney disease
BackgroundFor patients on dialysis with poor quality of life and prognosis, dialysis withdrawal and subsequent transition to palliative care is...
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Perineuronal nets affect memory and learning after synapse withdrawal
Perineuronal nets (PNNs) enwrap mature neurons, playing a role in the control of plasticity and synapse dynamics. PNNs have been shown to have...
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Predominant affective temperaments in depressive patients with severe social withdrawal
BackgroundHikikomori (HK) is characterized by self-isolation and social refusal, being more likely also associated with affective disorders,...
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An innovative inpatient protocol for alcohol withdrawal prevention in a 16-year-old adolescent: a case report
BackgroundAlcohol cessation in youth with daily drinking poses a risk of severe and life-threatening alcohol withdrawal. If unsupervised, alcohol...
