Search
Search Results
-
Treatment outcome of IDH1/2 wildtype CNS WHO grade 4 glioma histologically diagnosed as WHO grade II or III astrocytomas
BackgroundIsocitrate dehydrogenase ( IDH)1/2 wildtype (wt) astrocytomas formerly classified as WHO grade II or III have significantly shorter PFS and...
-
Diffusion histogram profiles predict molecular features of grade 4 in histologically lower-grade adult diffuse gliomas following WHO classification 2021
ObjectivesIn the latest World Health Organization classification 2021, grade 4 adult diffuse gliomas can be diagnosed with several molecular features...
-
Tumour growth rate predicts overall survival in patients with recurrent WHO grade 4 glioma
PurposeAccurate prognostication may aid in the selection of patients who will benefit from surgery at recurrent WHO grade 4 glioma. This study aimed...
-
Prognosis Individualized: Survival predictions for WHO grade II and III gliomas with a machine learning-based web application
WHO grade II and III gliomas demonstrate diverse biological behaviors resulting in variable survival outcomes. In the context of glioma prognosis,...
-
Perifocal edema is a risk factor for preoperative seizures in patients with meningioma WHO grade 2 and 3
BackgroundPatients with intracranial meningiomas frequently suffer from tumor-related seizures prior to resection, impacting patients’ quality of...
-
Long-term outcomes of CNS WHO grade 2 oligodendroglioma in adult patients: a single-institution experience
PurposeOligodendrogliomas (ODGs) are a subtype of diffuse lower-grade gliomas with overall survival of > 10 years. This study aims to analyze...
-
Associations between contrast-enhanced ultrasound features and WHO/ISUP grade of clear cell renal cell carcinoma: a retrospective study
BackgroundClear cell renal cell carcinoma (CCRCC) comprises 70%–80% of RCCs. The World Health Organization/International Society of Urology Pathology...
-
Long-term follow up of patients with WHO grade 2 oligodendroglioma
PurposeSince the introduction of the molecular definition of oligodendrogliomas based on isocitrate dehydrogenase ( IDH )-status and the...
-
Analysis of safety and efficacy of proton radiotherapy for IDH-mutated glioma WHO grade 2 and 3
PurposeProton beam radiotherapy (PRT) has been demonstrated to improve neurocognitive sequelae particularly. Nevertheless, following PRT, increased...
-
Loss of H3K27me3 in WHO grade 3 meningioma
Immunohistochemical quantification of H3K27me3 was reported to distinguish meningioma patients with an unfavorable prognosis but is not yet...
-
Is location more determining than WHO grade for long-term clinical outcome in patients with meningioma in the first two decades of life?
ObjectiveTo identify factors for tumor relapse and poor outcome in patients with meningiomas in the first two decades of life.
MethodsAll patients...
-
A comprehensive genomic study of 390 H3F3A-mutant pediatric and adult diffuse high-grade gliomas, CNS WHO grade 4
Malignant brain tumors, known as H3K27-altered diffuse midline glioma (DMG) and H3G34-mutant diffuse hemispheric glioma (DHG), can affect individuals...
-
Particle beam radiotherapy in the treatment of WHO grade 2 and 3 meningiomas: an early experience from Shanghai Proton and Heavy Ion Center
PurposeTo investigate the efficacy and safety of particle beam radiotherapy (PBRT) in the management of patients with WHO grade 2 and 3 meningiomas.
...
-
Radiomics predict the WHO/ISUP nuclear grade and survival in clear cell renal cell carcinoma
ObjectivesThis study aimed to assess the predictive value of radiomics derived from intratumoral and peritumoral regions and to develop a radiomics...
-
Decision system for extent of resection in WHO grade 3 gliomas: a Chinese Glioma Genome Atlas database analysis
BackgroundExtensive surgical resection has been found to be associated with longer survival in patients with gliomas, but the interactive prognostic...
-
Association of sex-specific abdominal adipose tissue with WHO/ISUP grade in clear cell renal cell carcinoma
ObjectivesTo explore the association between computed tomography (CT)-measured sex-specific abdominal adipose tissue and the pathological grade of...
-
Association of partial T2-FLAIR mismatch sign and isocitrate dehydrogenase mutation in WHO grade 4 gliomas: results from the ReSPOND consortium
PurposeWhile the T2-FLAIR mismatch sign is highly specific for isocitrate dehydrogenase (IDH)-mutant, 1p/19q-noncodeleted astrocytomas among...
-
Occurrence of non-central nervous system cancers during postoperative follow-up of patients who underwent surgery for a WHO grade II glioma: implications for therapeutic management
PurposeSurvival is currently prolonged in WHO grade II glioma (GIIG). Although exceptionally described, long-term survivors may develop second...
-
Combined utility of Ki-67 index and tumor grade to stratify patients with pancreatic ductal adenocarcinoma who underwent upfront surgery
ObjectiveTo investigate the prognostic prediction of a new indicator, combined by tumor grade and Ki-67, in patients with resected pancreatic ductal...
-
Integration of molecular pathology with histopathology to accurately evaluate the biological behaviour of WHO grade 2 meningiomas and patient prognosis
PurposeA molecular pathological grading method was tested in WHO grade 2 meningiomas to judge whether this molecular grading can more accurately...
