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Association of rs2282679 polymorphism in vitamin D binding protein gene (GC) with the risk of vitamin D deficiency in an iranian population: season-specific vitamin D status
BackgroundGenome-wide association studies in Western countries indicate a considerable impact of variations in vitamin D binding protein (GC) genes...
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Vitamin D receptor and vitamin D binding protein gene polymorphisms in patients with asthma: a pilot study
BackgroundThe effects of vitamin D are exerted by interaction with the vitamin D receptor (VDR) and vitamin D binding protein (VDBP). Polymorphisms...
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Alterations in circulating levels of vitamin D binding protein, total and bioavailability of vitamin D in diabetic retinopathy patients
AimsThis study aimed to investigate the association between circulating levels of vitamin D binding protein (VDBP) and its genotypes and diabetic...
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The association of vitamin D binding protein levels and genotypes with type 1 diabetes in the black South African population
BackgroundVitamin D deficiency and the vitamin D pathway have previously been associated with type 1 diabetes (T1D). The majority of vitamin D is...
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Modulation of the vitamin D/vitamin D receptor system in osteoporosis pathogenesis: insights and therapeutic approaches
Osteoporosis is a prevalent bone disorder characterized by low bone mineral density (BMD) and deteriorated bone microarchitecture, leading to an...
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Vitamin D and vitamin D receptor polymorphism in Asian adolescents with primary dysmenorrhea
BackgroundThe expression of vitamin D receptor in the normal endometrium and ovaries supports the role of vitamin D in local immunity and...
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Potential roles of vitamin D binding protein in attenuating liver injury in sepsis
BackgroundIn sepsis, vitamin D binding protein (VDBP) has been shown to be low-expressed. The current study examined the relationship between serum...
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Vitamin D metabolism in cancer: potential feasibility of vitamin D metabolism blocking therapy
In this review, we discuss the possibility of the vitamin D metabolizing enzyme CYP24A1 being a therapeutic target for various tumors including...
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Association of selected adipokines with vitamin D deficiency in children with inflammatory bowel disease
BackgroundAdipose tissue is significantly involved in inflammatory bowel disease (IBD). Vitamin D can affect both adipogenesis and inflammation. The...
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Vitamin D and Respiratory Diseases
The significance of Vitamin D has been appreciated beyond bone health and calcium metabolism. The importance of Vitamin D in respiratory health has...
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Dietary vitamin D intake and risk of colorectal cancer according to vitamin D receptor expression in tumors and their surrounding stroma
BackgroundColorectal Cancer (CRC) has been molecularly classified into several subtypes according to tumor, stromal, and immune components. Here, we...
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Vitamin D metabolic pathway genes polymorphisms and vitamin D levels in association with neonatal hyperbilirubinemia in China: a single-center retrospective cohort study
BackgroundNeonatal hyperbilirubinemia (NH) is a major cause of hospitalization after birth. Previous studies indicated that vitamin D deficiency...
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The Efficacy of Vitamin D Supplement in the Expression and Protein Levels of Endometrial Decidualization Factors in Women with Recurrent Implantation Failure
Recurrent implantation failure (RIF) is a challenging situation for infertility specialists, and its treatment is introduced as a difficult case in...
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Vitamin D3 supplementation improves spatial memory, muscle function, pain score, and modulates different functional physiological biomarkers in vitamin D3 deficiency diet (VDD)-induced rats model
BackgroundVitamin D Deficiency is recognized as a pandemic, which is associated with high mortality. An inadequate level of vitamin D is associated...
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FokI polymorphism of Vitamin D receptor gene and deficiency of serum Vitamin D increases the risk of breast cancer in North Indian women
IntroductionBreast cancer is a leading cause of cancer morbidity and mortality in females. Decreased availability of Vitamin D within breast cells,...
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Reduction in circulating vitamin D binding protein in patients with multiple sclerosis
BackgroundIn this study, we aimed to determine the risk association between vitamin D binding protein (VDBP) polymorphism in patients with multiple...
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Vitamin D and Toxic Metals in Pregnancy - a Biological Perspective
Purpose of ReviewTo discuss the potential biological mechanisms between vitamin D and toxic metals and summarize epidemiological studies examining...
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Optimisation of vitamin D status in global populations
AbstractVitamin D is important for musculoskeletal health. Concentrations of 25-hydroxyvitamin D, the most commonly measured metabolite, vary...
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Vitamin D status and leukocyte telomere length in middle childhood
Short telomere length is associated with chronic diseases and decreased lifespan. Vitamin D and its binding protein (DBP) may maintain telomeres...