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Advances in viscosupplementation and tribosupplementation for early-stage osteoarthritis therapy
Joint kinematic instability, arising from congenital or acquired musculoskeletal pathoanatomy or from imbalances in anabolism and catabolism induced...
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The efficacy of intraarticular viscosupplementation after arthroscopic partial meniscectomy: a randomized controlled trial
BackgroundThis study aimed to evaluate the efficacy of viscosupplementation after arthroscopic partial meniscectomy.
MethodA randomized controlled...
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A Review of the Clinical Effectiveness and Safety of Hybrid Cooperative Complexes in Intra-articular Viscosupplementation
Viscosupplementation by intra-articular (i.a.) injection of the non-sulfated glycosaminoglycan (GAG) hyaluronic acid (HA) is a conservative therapy...
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Bone marrow aspirate concentrate injections provide similar results versus viscosupplementation up to 24 months of follow-up in patients with symptomatic knee osteoarthritis. A randomized controlled trial
PurposeThe purpose of this double-blind randomized controlled trial (RCT) was to compare clinical improvement and radiographic findings up to 2 years...
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Demonstrating antibiotic stewardship while diagnosing and treating bilateral pseudoseptic arthritis: a case report
IntroductionAlthough viscosupplementation is a commonly used treatment for osteoarthritis and is widely regarded as a safe treatment option, it is...
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Viscosupplementation may preserve tibial cartilage and collagen in osteoarthritis: findings from a preclinical model of osteoarthritis
PurposeIntraarticular (IA) hyaluronic acid (HA) injection is used to reduce pain and improve mobility in knee osteoarthritis (OA). Little is known...
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To stop or not to stop novel oral anticoagulants prior to performing joint interventional maneuvers? Evidence from a prospective study that the therapy can be maintained
AbstractAnticoagulation is common in patients undergoing routine musculoskeletal interventional maneuvers. Previous retrospective studies have...
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Hyaluronic Acid Therapy in Hip OA Does Not Perform Equally in Osteoarthritis Secondary to Juvenile Idiopathic Arthritis When Compared to Primary Osteoarthritis: A 2-Year Preliminary Evaluation
ObjectiveHip involvement in juvenile idiopathic arthritis (JIA) is one of most important causes of pain and disability. Total hip arthroplasty (THA)...
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Konservative Optionen zur Therapie der Sprunggelenkarthrose
In this article the causes of arthritis in the region of the ankle are introduced and the conservative treatment options are described and discussed...
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Impact of obesity, structural severity and their combination on the efficacy of viscosupplementation in patients with knee osteoarthritis
BackgroundObesity and radiological severity have been identified to be independent predictors of a low rate of response to viscosupplementation (VS),...
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Impact of hyaluronic acid injection on the knee joint friction
PurposeThe purpose of this in vitro study was to investigate whether or not hyaluronic acid supplementation improves knee joint friction during...
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Viscosupplementation for Management of Knee Osteoarthritis from an Indian Perspective: An Expert Consensus Report
IntroductionKnee osteoarthritis (OA) is a progressive degenerative condition and is a significant contributor toward physical disability in the aging...
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Predictors for patient satisfaction of a single intra-articular injection of crosslinked hyaluronic acid combined with mannitol (HANOX-M-XL) in patients with temporomandibular joint osteoarthritis. Results of a prospective open-label pilot study (HAPPYMINI-ARTEMIS trial)
BackgroundChronic pain and functional impairment interfere with the quality of life of subjects suffering from temporomandibular joint (TMJ)...
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Non-Arthroplasty Surgical Treatments for Knee Osteoarthritis and Cartilage Damage: a 10 Year Update
Osteoarthritis is a chronic, degenerative disease leading to pain and decreased functionality in millions of people in the United States every year....
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Randomised, double-blind comparison of a fixed co-formulation of intra-articular polynucleotides and hyaluronic acid versus hyaluronic acid alone in the treatment of knee osteoarthritis: two-year follow-up
BackgroundA first-year interim analysis of this two-year study suggested that intra-articular injections of highly purified, natural-origin...
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Non-surgical Treatment Recommendations for Knee Osteoarthritis
Purpose of ReviewOsteoarthritis (OA) of the knee is a common disease with associated direct and indirect costs having a significant societal impact....
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Hylan G-F20 and galactomannan joint flares are associated to acute synovitis and release of inflammatory cytokines
BackgroundInjection of Hylan G-F20 (HY) into joints may provoke local flares, which mechanisms may involve reaction to protein contaminants. We have...
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Ultrasound-guided injection with hyaluronic acid in hip osteoarthritis: efficacy and safety in a real-life setting
BackgroundFor knee OA, EULAR has included hyaluronic acid (HA) intra-articular injection in the 2003 recommendations, making the intra-articular...
