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Outcomes of one-stage feminizing genitoplasty in children with congenital adrenal hyperplasia and severe virilization
PurposeTo present our surgical experience and outcomes in congenital adrenal hyperplasia (CAH) patients with severe virilization using a combined...
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Testosterone serum levels are not predictive of maternal virilization in hyperreactio luteinalis
BackgroundElevated concentrations of circulating testosterone are present in hyperreactio luteinalis (HL), a pregnancy-specific, self-limited...
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Rare virilizing tumor: ovarian steroid cell tumor, not otherwise specified: a case report
BackgroundOvarian steroid cell tumors, not otherwise specified is a rare sex cord-stromal tumor. Almost 60% of all steroid cell tumors are...
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Estimation of Reference Values for External Genitalia Parameters in North Indian Preterm and Term Female Newborns
ObjectivesTo establish gestation-wise normative data of external genitalia measurements in North Indian term and preterm female newborns.
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Laparoscopic assisted removal of large ovarian mass causing precocious puberty in an infant—a case report
BackgroundSex cord and stromal tumors are a heterogeneous group of tumors that arise from gonadal sex cord cells, gonadal stromal cells, or both....
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Pubertal development in 46,XY patients with NR5A1 mutations
PurposeMutations in the NR5A1 gene, encoding the transcription factor Steroidogenic Factor-1, are associated with a highly variable genital...
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Adrenal carcinoma: a case report
BackgroundAdrenocortical carcinoma is a rare malignancy (0.5–2 cases/million/year) with a poor prognosis. Hypercortisolism, virilization, and...
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Puberty and Bone Health in Chronic Disease
Linear growth, onset of and progress through puberty are all adversely affected by chronic diseases during childhood and adolescence. Peak bone mass...
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Ovarian steroid cell tumors, not otherwise specified: analysis of nine cases with a literature review
BackgroundOvarian steroid cell tumors (SCTs), not otherwise specified (NOS), are rare, with few large studies. The purpose of this study was to...
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Postmenopausal onset of androgen excess: a diagnostic and therapeutic algorithm based on extensive clinical experience
PurposePostmenopausal hyperandrogenism is a rare condition that requires identifying those women bearing a life-threatening tumor. We aimed to study...
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Androgen insensitivity syndrome: a review
PurposeAndrogen insensitivity syndrome (AIS) is a disorder characterized by peripheral androgen resistance due to androgen receptor mutations in...
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Long-term Prophylaxis with Androgens in the management of Hereditary Angioedema (HAE) in emerging countries
Hereditary angioedema (HAE) is a rare autosomal dominant genetic disease characterized by repetitive subcutaneous or submucosal angioedema,...
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Safety of gender affirming treatment in assigned female at birth transgender people and association of androgen and estrogen β receptor polymorphisms with clinical outcomes
PurposeGender affirming hormone treatment (GAHT) with androgens in assigned female at birth (AFAB) people with Gender Incongruence (GI) can induce...
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Sexual function of transgender assigned female at birth seeking gender affirming care: a narrative review
Sexual health is pivotal to the overall health and well-being of individuals. To date, transgender persons’ sexual function results to be poorly...
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Recurrent maternal virilization during pregnancy in patients with PCOS: two clinical cases
BackgroundMaternal virilization during pregnancy is a rare phenomenon. Polycystic ovary syndrome (PCOS), luteoma and luteinic cysts are the most...
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Feminizing adrenocortical adenoma in a girl from a resource-limited setting: a case report
BackgroundAn adrenocortical tumor is a rare tumor in pediatrics, which can be functional or nonfunctional. Functional tumors present with...
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A rare ovarian hilus cell tumour accompanying bilateral serous cystadenomas: report of a case
BackgroundHilus cell tumours is considered an uncommon branch of androgen producing neoplasms that accounts for < 5% of all ovarian tumours. They are...
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Imaging features of intra-abdominal and intra-pelvic causes of hirsutism
Hirsutism is a relatively common disorder which affects approximately 5% to 15% of women. It is defined by excessive growth of terminal hair in...
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Efficacy of topical minoxidil in enhancing beard growth in a group of transgender assigned female at birth individuals on gender affirming hormone therapy
PurposeTestosterone therapy represents the cornerstone of gender affirming hormone therapy (GAHT) among t-AFAB (transgender Assigned Female At Birth)...
