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Personalized ventilatory strategy based on lung recruitablity in COVID-19-associated acute respiratory distress syndrome: a prospective clinical study
BackgroundHeterogeneity is an inherent nature of ARDS. Recruitment-to-inflation ratio has been developed to identify the patients who has lung...
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High-flow nasal cannula therapy with sequential noninvasive ventilation versus noninvasive ventilation alone as the initial ventilatory strategy in acute COPD exacerbations: study protocol for a randomized controlled trial
BackgroundNoninvasive ventilation (NIV) is the recommended mode of ventilation used in acute respiratory failure secondary to an acute exacerbation...
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Diagnostic and prognostic value of ventilatory power in pulmonary hypertension
BackgroundVentilatory power is a novel index which could reflect both ventilation efficiency and peripheral blood flow. However, its clinical value...
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The Diaphragmatic Initiated Ventilatory Assist (DIVA) trial: study protocol for a randomized controlled trial comparing rates of extubation failure in extremely premature infants undergoing extubation to non-invasive neurally adjusted ventilatory assist versus non-synchronized nasal intermittent positive pressure ventilation
BackgroundInvasive mechanical ventilation contributes to bronchopulmonary dysplasia (BPD), the most common complication of prematurity and the...
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Development and assessment of the performance of a shared ventilatory system that uses clinically available components to individualize tidal volumes
ObjectivesTo develop and assess a system for shared ventilation using clinically available components to individualize tidal volumes.
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Effects of changes in trunk inclination on ventilatory efficiency in ARDS patients: quasi-experimental study
BackgroundTrunk inclination from semirecumbent head-upright to supine-flat positioning reduces driving pressure and increases respiratory system...
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The effect of intraoperative transnasal humidified rapid-insufflation ventilatory exchange on emergence from general anesthesia in patients undergoing microlaryngeal surgery: a randomized controlled trial
BackgroundTransnasal humidified rapid-insufflation ventilatory exchange (THRIVE) has received extensive attention for its utility in tubeless...
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Non-invasive ventilation in neuromuscular diseases: should we use higher levels of ventilatory support?
PurposeIn patients with COPD, one of the leading indications for domiciliary non-invasive ventilation (NIV), a major paradigm shift has been observed...
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Ten rules for optimizing ventilatory settings and targets in post-cardiac arrest patients
Cardiac arrest (CA) is a major cause of morbidity and mortality frequently associated with neurological and systemic involvement. Supportive...
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Comparison of neurally adjusted ventilatory assist and synchronized intermittent mandatory ventilation in preterm infants after patent ductus arteriosus ligation: a retrospective study
ObjectiveThis study aimed to compare the efficacy of neurally adjusted ventilatory assist (NAVA) to synchronized intermittent mandatory ventilation...
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Respiratory challenges and ventilatory management in different types of acute brain-injured patients
Acute brain injury (ABI) covers various clinical entities that may require invasive mechanical ventilation (MV) in the intensive care unit (ICU). The...
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Established severe BPD: is there a way out? Change of ventilatory paradigms
AbstractImproved survival of extremely preterm newborn infants has increased the number of infants at risk for develo** bronchopulmonary dysplasia...
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Heart Rate Variability-Derived Thresholds for Exercise Intensity Prescription in Endurance Sports: A Systematic Review of Interrelations and Agreement with Different Ventilatory and Blood Lactate Thresholds
BackgroundExercise intensities are prescribed using specific intensity zones (moderate, heavy, and severe) determined by a ‘lower’ and a ‘higher’...
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Effects of an open lung extubation strategy compared with a conventional extubation strategy on postoperative pulmonary complications after general anesthesia: a single-centre pilot randomized controlled trial
PurposePostoperative pulmonary complications (PPCs) are a common cause of morbidity. Postoperative atelectasis is thought to be a significant risk...
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Transnasal Humidified Rapid Insufflation Ventilatory Exchange in children requiring emergent intubation (Kids THRIVE): a statistical analysis plan for a randomised controlled trial
The placement of an endotracheal tube for children with acute or critical illness is a low-frequency and high-risk procedure, associated with high...
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Ventilatory settings in the initial 72 h and their association with outcome in out-of-hospital cardiac arrest patients: a preplanned secondary analysis of the targeted hypothermia versus targeted normothermia after out-of-hospital cardiac arrest (TTM2) trial
PurposeThe optimal ventilatory settings in patients after cardiac arrest and their association with outcome remain unclear. The aim of this study was...
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Neurally adjusted ventilatory assist as a weaning mode for adults with invasive mechanical ventilation: a systematic review and meta-analysis
BackgroundProlonged ventilatory support is associated with poor clinical outcomes. Partial support modes, especially pressure support ventilation,...
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Lung (extracorporeal CO2 removal) and renal (continuous renal replacement therapy) support: the role of ultraprotective strategy in Covid 19 and non-Covid 19 ARDS. A case-control study
BackgroundPreliminary studies suggest that moderate ARDS and acute renal failure might benefit from extracorporeal CO 2 removal (ECCO 2 R) coupled with...
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High flow nasal therapy versus noninvasive ventilation as initial ventilatory strategy in COPD exacerbation: a multicenter non-inferiority randomized trial
BackgroundThe efficacy and safety of high flow nasal therapy (HFNT) in patients with acute hypercapnic exacerbation of chronic obstructive pulmonary...
