Search
Search Results
-
Seasonal variations in endothelium-dependent flow-mediated vasodilation and endothelium-independent nitroglycerine-induced vasodilation
Cardiovascular mortality has been shown to vary seasonally. However, it has not been determined whether vascular function is affected by the season....
-
TMAO Impairs Mouse Aortic Vasodilation by Inhibiting TRPV4 Channels in Endothelial Cells
Trimethylamine oxide (TMAO) is an intestinal flora metabolite associated with risk of cardiovascular diseases. Transient receptor potential vanilloid...
-
New device for assessment of endothelial function: plethysmographic flow-mediated vasodilation (pFMD)
Measurement of flow-mediated vasodilation (FMD) in the brachial artery by using ultrasound is a well-established technique for evaluating endothelial...
-
Aerobic exercise improves BKCa channel-mediated vasodilation in diabetic vascular smooth muscle via AMPK/Nrf2/HO-1 pathway
AimsThis study aims to investigate the effect of aerobic exercise training on BK Ca channel in diabetic vascular smooth muscle and explore the...
-
Absorbed Bioactive Compounds Replicate Guanxin II-Induced Endothelium-Associated in/ex vivo Vasodilation
ObjectiveTo develop an interference-free and rapid method to elucidate Guanxin II (GX II)’s representative vasodilator absorbed bioactive compounds...
-
Effects of nitroglycerin-induced vasodilation on elastic and muscular artery stiffness in older Veterans
Vascular smooth muscle tone may play an important role in the physiology of increased arterial stiffness that occurs with aging. This study evaluated...
-
Endothelial and exercise vasodilation are reduced in postmenopausal females with obesity versus lean and overweight
BackgroundObesity (OB) is highly prevalent in females after menopause, especially visceral adipose tissue (VAT) accumulation which contributes to...
-
Silybin induces endothelium-dependent vasodilation via TRPV4 channels in mouse mesenteric arteries
Silybin is a flavonolignan extracted from the seeds of Silybum marianum that has been used as a dietary supplement for treating hepatic diseases and...
-
Mitochondrial DNA integrity and function are critical for endothelium-dependent vasodilation in rats with metabolic syndrome
Endothelial dysfunction in diabetes is generally attributed to oxidative stress, but this view is challenged by observations showing antioxidants do...
-
NADPH oxidase 4 contributes to TRPV4-mediated endothelium-dependent vasodilation in human arterioles by regulating protein phosphorylation of TRPV4 channels
Impaired endothelium-dependent vasodilation has been suggested to be a key component of coronary microvascular dysfunction (CMD). A better...
-
The effect of Lu AG09222 on PACAP38- and VIP-induced vasodilation, heart rate increase, and headache in healthy subjects: an interventional, randomized, double-blind, parallel-group, placebo-controlled study
BackgroundPituitary adenylate cyclase-activating polypeptide (PACAP), structurally related to vasoactive intestinal peptide (VIP), is one of the...
-
Evaluating the Effect of Compound Solution of Papaverine, Lidocaine, and Heparin on Vasodilation of Vessels for Microvascular Anastomosis
Topical application of 3 vasodilators has been used in 19 patients and 20 free flaps to facilitate microvascular anastomosis. The author by hit and...
-
Short stature is associated with low flow-mediated vasodilation in Japanese men
An inverse association between height and the risk of cardiovascular disease has been reported. The objective of this study was to examine the...
-
Mechanism of the switch from NO to H2O2 in endothelium-dependent vasodilation in diabetes
Coronary microvascular dysfunction is prevalent among people with diabetes and is correlated with cardiac mortality. Compromised...
-
Nitric oxide storage levels modulate vasodilation and the hypotensive effect induced by photobiomodulation using an aluminum gallium arsenide (AlGaAs) diode laser (660 nm)
The aim of this study was to evaluate the participation of nitric oxide (NO) in the hypotensive and vasorelaxation effect induced by PBM using an...
-
Pharmacodynamic Mechanism of Kuanxiong Aerosol for Vasodilation and Improvement of Myocardial Ischemia
ObjectiveTo explore the effect of Kuanxiong Aerosol (KXA) on isoproterenol (ISO)-induced myocardial injury in rat models.
MethodsTotally 24 rats...
-
Violet LED induces vasodilation in rat aortic rings by soluble guanylate cyclase–dependent mechanism and increases SOD activity
We found several studies that have used the aortic rings as an experimental model, mainly for the testing of new drugs or new therapies that try to...
-
Pulmonary vasodilation by sildenafil in acute intermediate-high risk pulmonary embolism: a randomized explorative trial
BackgroundTo investigate if acute pulmonary vasodilation by sildenafil improves right ventricular function in patients with acute intermediate-high...
