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Improving the diagnosis of active tuberculosis: a novel approach using magnetic particle-based chemiluminescence LAM assay
ObjectivesTuberculosis (TB) is a significant global health concern, given its high rates of morbidity and mortality. The diagnosis using urine...
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Role of detection of lipoarabinomannan (LAM) in urine for diagnosis of pulmonary tuberculosis in HIV patients: Egyptian experience
BackgroundTuberculosis remains a worldwide problem fueled by the HIV epidemic. TB infection impacts HIV progression and mortality even with...
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Diagnostic accuracy of Lipoarabinomannan detection by lateral flow assay in pleural tuberculosis
BackgroundLipoarabinomannan (LAM) antigen serves as an attractive biomarker to diagnose Tuberculosis (TB). Given the limitations of current...
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Risk factor mining and prediction of urine protein progression in chronic kidney disease: a machine learning- based study
BackgroundChronic kidney disease (CKD) is a global public health concern. Therefore, to provide timely intervention for non-hospitalized high-risk...
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Determine TB-LAM point-of-care tuberculosis assay predicts poor outcomes in outpatients during their first year of antiretroviral therapy in South Africa
BackgroundDetermine TB-LAM is the first point-of-care test (POC) for HIV-associated tuberculosis (TB) and rapidly identifies TB in those at high-risk...
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Implementation of a rapid diagnostic assay package for cryptococcosis, histoplasmosis and tuberculosis in people living with HIV in Paraguay
BackgroundOpportunistic infections (OIs) are common causes of mortality among people living with HIV (PLHIV). We determined prevalence and 30-day...
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Implementation of tuberculosis and cryptococcal meningitis rapid diagnostic tests amongst patients with advanced HIV at Kamuzu Central Hospital, Malawi, 2016–2017
BackgroundCryptococcal meningitis (CM) and tuberculosis (TB) remain leading causes of hospitalization and death amongst people living with HIV,...
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Accuracy of the tuberculosis point-of-care Alere determine lipoarabinomannan antigen diagnostic test using α-mannosidase treated and untreated urine in a cohort of people living with HIV in Guatemala
BackgroundImproved point-of-care diagnostic tests for tuberculosis (TB) in severe immune suppressed people living with HIV (PLWH) are needed to...
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Testing novel strategies for patients hospitalised with HIV-associated disseminated tuberculosis (NewStrat-TB): protocol for a randomised controlled trial
BackgroundHIV-associated tuberculosis (TB) contributes disproportionately to global tuberculosis mortality. Patients hospitalised at the time of the...
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Perioperative management of thoracic surgery in patients with lymphangioleiomyomatosis
BackgroundGeneral surgery for patients with lymphangioleiomyomatosis (LAM) is infrequent, however, general surgeons also occasionally experience it....
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Study on Fine-Grained Visual Classification of Low-Resolution Urinary Erythrocyte
The morphological analysis test item of urine red blood cells is referred to as “extracorporeal renal biopsy,” which holds significant importance for...
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A stool based qPCR for the diagnosis of TB in children and people living with HIV in Uganda, Eswatini and Mozambique (Stool4TB): a protocol for a multicenter diagnostic evaluation
BackgroundTuberculosis (TB) is a major cause of mortality worldwide. Children and people living with HIV (PLHIV) have an increased risk of mortality,...
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Usefulness of transperineal shear wave elastography of levator ani muscle in women with stress urinary incontinence
This study aimed to quantitatively assess the quality of levator ani muscle (LAM) using shear wave elastography (SWE) and to evaluate the association...
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Study of female pelvic floor muscle in overactive bladder based on MRI 3D reconstruction
BackgroundThis study examined the three-dimensional (3D) morphological changes of the urination and urinary continence anatomical structures in...
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Advanced HIV disease management practices within inpatient medicine units at a referral hospital in Zambia: a retrospective chart review
BackgroundZambia recently achieved UNAIDS 90-90-90 treatment targets for HIV epidemic control; however, inpatient facilities continue to face a large...
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Gene mutations in sporadic lymphangioleiomyomatosis and genotype–phenotype correlation analysis
BackgroundSporadic lymphangioleiomyomatosis (S-LAM) is a rare neoplasm with heterogeneous clinical features that is conventionally considered to be...
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Pelvic floor parameters predict postpartum stress urinary incontinence: a prospective MRI study
ObjectiveTo investigate the pelvic floor changes in primiparas with postpartum stress urinary incontinence (SUI) after vaginal delivery using pelvic...
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Methylprednisolone in the treatment of lymphangioleiomyomatosis
This case report proposes the use of pulsed methylprednisolone in a patient with lymphangioleiomyomatosis (LAM) who was invasively ventilated. A...
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Episiotomy in vacuum extraction, do we cut the levator ani muscle? A prospective cohort study
Introduction and hypothesisVaginal delivery may lead to levator ani muscle (LAM) injury or avulsion. Episiotomy may reduce obstetric anal sphincter...
