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Colorectal cancer with synchronous unresectable liver metastases: resecting the primary tumor improves survival
PurposeThe optimal treatment strategy of patients affected by colorectal cancer (CRC) with synchronous unresectable liver metastases (SULM) is at...
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Pathological complete response of initially unresectable multiple liver metastases achieved using combined peptide receptor radionuclide therapy and somatostatin analogs following pancreatic neuroendocrine tumor resection: a case report
BackgroundPeptide receptor radionuclide therapy (PRRT) serves as a novel and effective treatment option for somatostatin receptor-positive...
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Laparoscopic Portal Vein Ligation and Embolization During First-Stage Hepatectomy for Initially Unresectable Colorectal Liver Metastases
BackgroundTwo-stage hepatectomy (TSH) is the only treatment for the patients with multiple bilobar colorectal liver metastases (CRMs) who are not...
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Combined Hepatic Arterial Infusion Pump and Systemic Chemotherapy in the Modern Era for Chemotherapy-Naive Patients with Unresectable Colorectal Liver Metastases
PurposeChemotherapy-naive patients with unresectable colorectal liver metastases (CRLM) have been the best responders to hepatic arterial infusion...
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Intersurgeon Variability in Local Treatment Planning for Patients with Initially Unresectable Colorectal Cancer Liver Metastases: Analysis of the Liver Expert Panel of the Dutch Colorectal Cancer Group
BackgroundConsensus on resectability criteria for colorectal cancer liver metastases (CRLM) is lacking, resulting in differences in therapeutic...
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Retrospective analysis of colorectal cancer patients with metachronous initially unresectable liver metastases (and no other) achieving no evidence of disease after first-line comprehensive therapy: a multicenter real-world study
PurposeTo explore the optimal timing of locoregional therapy in patients with colorectal cancer (CRC) recurrence after radical resection and...
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Outcomes of Hepatic Artery-Based Therapies and Systemic Multiagent Chemotherapy in Unresectable Colorectal Liver Metastases: A Systematic Review and Meta-analysis
BackgroundTreatment of unresectable colorectal liver metastases (UCRLM) includes locoregional and systemic therapy. A comprehensive analysis...
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A Modified Floxuridine Reduced-Dose Protocol for Patients with Unresectable Colorectal Liver Metastases Treated with Hepatic Arterial Infusion
BackgroundMost patients treated with the standard dosing protocol (SDP) of hepatic arterial infusion (HAI) floxuridine require dose holds and...
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Metabolic tumor volume predicts long-term survival after transplantation for unresectable colorectal liver metastases: 15 years of experience from the SECA study
ObjectiveTo report 15 years of experience with metabolic tumor volume (MTV) of liver metastases from the preoperative 18 F-FDG PET/CT to predict...
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Unresectable Intermediate-Size (3–5 cm) Colorectal Liver Metastases: Stereotactic Ablative Body Radiotherapy Versus Microwave Ablation (COLLISION-XL): Protocol of a Phase II/III Multicentre Randomized Controlled Trial
BackgroundAlthough microwave ablation (MWA) has a low complication rate and good efficacy for small-size (≤ 3 cm) colorectal liver metastases (CRLM),...
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The Role of Liver Transplantation in the Treatment of Liver Metastases from Neuroendocrine Tumors
Transplant oncology is a new field of medicine referred to the use of solid organ transplantation, particularly the liver, to improve prognosis and...
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Successful R0 resection after chemotherapy, including nivolumab, for gastric cancer with liver metastases: three case reports
BackgroundAdvances in chemotherapy have increased clinical experience with conversion surgery for inoperable advanced gastric cancer. This report...
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Advancements in the Management of Synchronous Colorectal Liver Metastases: A Comprehensive Review of Surgical, Systemic, and Local Treatment Modalities
Purpose of ReviewThis review addresses the current landscape of colorectal cancer (CRC) with a focus on liver metastases, the third most common...
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Gemcitabine with Cisplatin Versus Hepatic Arterial Infusion Pump Chemotherapy for Liver-Confined Unresectable Intrahepatic Cholangiocarcinoma
BackgroundA post-hoc analysis of ABC trials included 34 patients with liver-confined unresectable intrahepatic cholangiocarcinoma (iCCA) who received...
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Liver Transplantation for Nonresectable Colorectal Liver Metastases (CRLM)
Transplantation represents the most radical locoregional therapy through removal of the liver, associated vasculature and locoregional lymph nodes,...
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Predictive Parameters in Patients Undergoing Percutaneous Hepatic Perfusion with Melphalan for Unresectable Liver Metastases from Uveal Melanoma: A Retrospective Pooled Analysis
PurposeThe aim of this study was to identify positive predictors for survival in uveal melanoma (UM) patients treated with percutaneous hepatic...
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Deep learning models for automatic tumor segmentation and total tumor volume assessment in patients with colorectal liver metastases
BackgroundWe developed models for tumor segmentation to automate the assessment of total tumor volume (TTV) in patients with colorectal liver...
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Current Management of Neuroendocrine Tumour Liver Metastases
Purpose of reviewThis article aims to illustrate the current state of investigations and management of liver metastases in patients with...
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Where Are We Now with Liver Transplantation in Neuroendocrine Neoplasms? The Place of Liver Transplantation for Grades 1 and 2 Well-Differentiated Unresectable Liver Metastatic Neuroendocrine Tumours
Purpose of ReviewThis review outlines the role of liver transplantation in selected patients with unresectable neuroendocrine tumour liver...
