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A deep learning model for discriminating true progression from pseudoprogression in glioblastoma patients
IntroductionGlioblastomas (GBMs) are highly aggressive tumors. A common clinical challenge after standard of care treatment is differentiating tumor...
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Progression independent of relapse activity in relapsing multiple sclerosis: impact and relationship with secondary progression
ObjectivesWe investigated the occurrence and relative contribution of relapse-associated worsening (RAW) and progression independent of relapse...
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Differentiating tumour progression from pseudoprogression in glioblastoma patients: a monoexponential, biexponential, and stretched-exponential model-based DWI study
BackgroundTo investigate the diagnostic performance of parameters derived from monoexponential, biexponential, and stretched-exponential...
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Low rCBV values in glioblastoma tumor progression under chemoradiotherapy
PurposeAfter standard treatment for glioblastoma, perfusion MRI remains challenging for differentiating tumor progression from post-treatment...
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Progression-free survival, disease-free survival and other composite end points in oncology: improved reporting is needed
Composite outcome measures such as progression-free survival and disease-free survival are increasingly used as surrogate end points in oncology...
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Endovascular coil-embolization of an unruptured, true UAA during early pregnancy- a case report
BackgroundTrue uterine artery aneurysms, especially during pregnancy, are a rare entity and not well understood. Clinical symptoms are unspecific...
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Two sample Mendelian Randomisation using an outcome from a multilevel model of disease progression
Identifying factors that are causes of disease progression, especially in neurodegenerative diseases, is of considerable interest. Disease...
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Detection and agreement of event-based OCT and OCTA analysis for glaucoma progression
ObjectiveTo examine event-based glaucoma progression using optical coherence tomography (OCT) and OCT angiography (OCTA).
MethodsIn this...
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A clinical model to predict the progression of knee osteoarthritis: data from Dryad
BackgroundKnee osteoarthritis (KOA) is a multifactorial, slow-progressing, non-inflammatory degenerative disease primarily affecting synovial joints....
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Genome-wide DNA methylation analysis related to ALS patient progression and survival
BackgroundEpigenetics contributes to the pathogenesis of amyotrophic lateral sclerosis (ALS). We aimed to characterize the DNA methylation profiles...
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Pulmonary Fibrosis Diagnosis and Disease Progression Detected Via Hair Metabolome Analysis
BackgroundFibrotic interstitial lung disease is often identified late due to non-specific symptoms, inadequate access to specialist care, and...
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Coil Embolization of True, Common and Proper, Hepatic Artery Aneurysms: Technique, Safety and Outcome
PurposeTo retrospectively assess the safety and efficacy of coil embolization for catheter-directed true common and proper hepatic artery aneurysm...
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Predictors of progression of multiple sclerosis in a sample of Egyptian patients
BackgroundMultiple sclerosis (MS) is a multifactorial neurodegenerative autoimmune disease with a varied clinical course and presentation, which is...
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Pursuing Clinical Predictors and Biomarkers for Progression in ILD: Analysis of the Pulmonary Fibrosis Foundation (PFF) Registry
IntroductionPulmonary fibrosis is a characteristic of various interstitial lung diseases (ILDs) with differing etiologies. Clinical trials in...
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WDR1 promotes prostate cancer progression through Wnt/β-catenin signaling
Prostate cancer (PCa) is the second most common cancer and the fifth leading cause of cancer-related death among men. A comprehensive understanding...
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Integrated FDG-PET/CT contribution over cross-sectional imaging in recurrence or progression of pancreaticobiliary neoplasms
PurposeWe aim to compare FDG-PET/CT and cross-sectional imaging (contrastenhanced CT/MRI) diagnostic abilities in detecting recurrence/progression of...
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Keratectasia severity staging and progression assessment based on the biomechanical E-staging
Until recently, corneal topography has been the gold standard in detecting keratectasia and monitoring its progression. The recently introduced ABCD...
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Alternative splicing in prostate cancer progression and therapeutic resistance
Prostate cancer (CaP) remains the second leading cause of cancer deaths in western men. CaP mortality results from diverse molecular mechanisms that...
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Sodium and water dynamics in the progression of chronic kidney disease: mechanisms and clinical significance
AimLifestyle modifications can postpone the progression of chronic kidney disease toward its terminal stage. This mini-review aims to explore the...
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Can blood-based markers predict RECIST progression in non-small cell lung cancer treated with immunotherapy?
PurposeIn this study, we aimed to evaluate the potential of routine blood markers, serum tumour markers and their combination in predicting...
