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Troponin elevation as a marker of short deterioration and one-year death in a high-risk surgical patient cohort in a low and middle income country setting: a postoperative approach to increase surveillance
PurposeMyocardial injury after noncardiac surgery is common and mostly asymptomatic. The ideal target population that will benefit from routine...
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Magnitude of troponin elevation in patients with biomarker evidence of myocardial injury: relative frequency and outcomes in a cohort study across a large healthcare system
BackgroundSerum troponin levels correlate with the extent of myocyte necrosis in acute myocardial infarction (AMI) and predict adverse outcomes....
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Cardiac dysfunction and high-sensitive C-reactive protein are associated with troponin T elevation in ischemic stroke: insights from the SICFAIL study
BackgroundTroponin elevation is common in ischemic stroke (IS) patients. The pathomechanisms involved are incompletely understood and comprise...
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GRACE scores or high-sensitivity troponin for timing of coronary angiography in non-ST-elevation acute coronary syndromes
BackgroundThe GRACE risk score is generically recommended by guidelines for timing of invasive coronary angiography without stating which score...
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Clinical and organizational impact of the use of different cardiac troponin assays for the diagnosis of myocardial infarction without persistent elevation of the ST segment at presentation (NSTEMI) in 12 Italian emergency departments (EDs): the TROCAR study
The management of acute chest pain is one of the challenges for emergency departments (EDs) worldwide. This study aims to provide insights into...
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Troponin dependent 30-day mortality in patients with acute pulmonary embolism
Background: Troponin concentrations above upper reference are associated with increased mortality in patients with pulmonary embolism (PE). We aimed...
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Current Evidence for the Use of High-Sensitivity Troponin Assays in the Emergency Department
Purpose of ReviewThis paper will review the published literature on the implementation of high-sensitivity troponin in the diagnosis and treatment of...
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High-Sensitivity Cardiac Troponin Algorithms and the Value of Likelihood Ratios
High-sensitivity cardiac troponin (hs-cTn) is now the recommended biomarker for diagnosis of non-ST-elevation myocardial infarction, but proper...
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Troponin as a predictor of outcomes in transcatheter aortic valve implantation: systematic review and meta-analysis
BackgroundTranscatheter aortic valve implantation (TAVI) is emerging as a therapeutic gold standard in the management of aortic stenosis. However,...
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Cardiovascular biomarkers: exploring troponin and BNP applications in conditions related to carbon monoxide exposure
BackgroundThe diagnosis and prognosis of cardiovascular disorders are greatly aided by cardiovascular biomarkers. The uses of troponin and B-type...
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Effect of a national guideline on postoperative troponin surveillance: a retrospective cohort study
PurposeWe aimed to evaluate the effect of the 2017 Canadian Cardiovascular Society (CCS) guidelines on troponin surveillance after noncardiac surgery.
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Serum Troponin I Assessments in 5- to 30-Year-Olds After BNT162b2 Vaccination
IntroductionRare myocarditis and pericarditis cases have occurred in coronavirus disease 2019 (COVID-19) messenger RNA (mRNA) vaccine recipients....
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Prognostic significance of troponin in patients with malignancy (NIHR Health Informatics Collaborative TROP-MALIGNANCY study)
BackgroundCardiac troponin is commonly raised in patients presenting with malignancy. The prognostic significance of raised troponin in these...
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Prognostic Implications of Coronary Artery Sclerosis in Troponin-Positive Patients with Non-Obstructive Coronary Arteries
IntroductionCoronary sclerosis is a risk factor for the progression to obstructive coronary artery disease (CAD). However, understanding its impact...
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High sensitivity troponin-I threshold to predict perioperative myocardial infarction
BackgroundHigh-sensitivity Troponin I (hs-cTnI) has largely replaced conventional troponin assays in an effort to improve detection of myocardial...
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Postoperative Troponin Levels in Children Undergoing Open Heart Surgery With and Without Coronary Intervention
We aimed to characterize the ranges, temporal trends, influencing factors, and prognostic significance of postoperative troponin levels after...
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Troponin I New Biomarker in Traumatic Brain Injury
Mortality in traumatic brain injury (TBI) is thought to be pathology in the heart-brain axis but its effect on the prognosis of traumatic brain...
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Differentiating Cardiac Troponin Levels During Cardiac Myosin Inhibition or Cardiac Myosin Activation Treatments: Drug Effect or the Canary in the Coal Mine?
Purpose of ReviewCardiac myosin inhibitors (CMIs) and activators are emerging therapies for hypertrophic cardiomyopathy (HCM) and heart failure with...
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The impact of sleep disordered breathing on cardiac troponin in acutely decompensated heart failure
PurposeSleep disordered breathing in decompensated heart failure has physiological consequences (e.g., intermittent hypoxemia) that may predispose to...
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Improved Utilization of Serial Testing Without Increased Admissions after Implementation of High-Sensitivity Troponin I: a Controlled Retrospective Cohort Study
BackgroundGuidelines recommend high-sensitivity cardiac troponin (hs-cTn) for diagnosis of myocardial infarction. Use of hs-cTn is increasing across...