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Bone turnover decreases and bone structure improves during treatment with weekly high-dose methylprednisolone for 12 weeks in Graves’ orbitopathy
PurposeWeekly treatment with the intravenous glucocorticoid methylprednisolone for 12 weeks is mainstay in the treatment of Graves’ orbitopathy but...
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Clinical observation of menopause hormone therapy in postmenopausal women with euthyroid and mild subclinical hypothyroidism
BackgroundTo evaluate the endocrine hormone and metabolic indices in postmenopausal women with euthyroid and mild subclinical hypothyroidism after...
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Pleiomorphism plurihormonal Pit-1-positive macroadenoma with central hyperthyroidism: a rare case report and literature review
BackgroundThyrotropin-secreting pituitary neuroendocrine tumors (PitNETs) are rare pituitary adenomas that are occasionally accompanied by...
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Subclinical thyroid dysfunction and autoantibodies in acute ischemic and hemorrhagic stroke patients: relation to long term stroke outcome
BackgroundData regarding the relation between both subclinical thyroid dysfunction, thyroid autoantibodies and clinical outcomes in stroke patients...
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The prevalence of thyroid dysfunction in Jordan: a national population-based survey
BackgroundThe objectives of this study are to assess the prevalence of clinical and subclinical hypo- and hyperthyroidism and their associated...
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Primary hypothyroidism and quality of life
In the 1970s, treatment with thyroid extract was superseded by levothyroxine, a synthetic l form of tetraiodothyronine. Since then, no major...
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Thyroid dysfunction in COVID-19
The COVID-19 pandemic has affected over 772 million people globally. While lung damage is the major contributor to the morbidity and mortality of...
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The ageing thyroid: implications for longevity and patient care
Thyroid hormones have vital roles in development, growth and energy metabolism. Within the past two decades, disturbances in thyroid hormone action...
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Influence of thyroid autoimmunity at various clinical stages of hypothyroidism on the risk of miscarriage before 20 weeks of gestation
PurposeWe aimed to clarify the influence of thyroid autoantibodies at various clinical stages of hypothyroidism on the risk of pregnancy loss before...
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Paediatric hepatic angiosarcoma with consumptive hypothyroidism—an important diagnostic pitfall to avoid during evaluation of hepatic vascular tumours
Hepatic angiosarcoma is an extremely rare primary malignant vascular tumour in children with very poor prognosis. Radiological diagnosis of hepatic...
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Safety and Pharmacokinetics of HRS-2261, a P2X3 Receptor Antagonist, in Healthy Subjects: A Randomized, Double-Blind, Placebo-Controlled Phase 1 Study
BackgroundP2X3 receptor antagonists hold promising potential as a therapeutic option for patients with refractory or unexplained chronic cough, a...
