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Racial disparities in treatment-related cardiovascular toxicities amongst women with breast cancer: a sco** review
PurposeBlack women often experience poorer breast cancer-related outcomes and higher mortality than white women. A contributor to this disparity may...
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Measuring symptoms and toxicities: a 35-year experience
PurposeWhen conducting trials aimed at the improvement of cancer-related and/or cancer treatment-related toxicities, it is important to determine the...
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Gastrointestinal toxicities of proteasome inhibitor therapy
PurposeProteasome inhibitors (PIs), which cause cell death via tumor suppressor and pro-apoptotic proteins, are integral to treatment of many...
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Toxicities from BRAF and MEK Inhibitors: Strategies to Maximize Therapeutic Success
Purpose of ReviewThis report highlights several of the recent therapeutic advancements in the treatment of BRAF -mutant tumors, discusses the most...
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Current understanding and management of CAR T cell-associated toxicities
Chimeric antigen receptor (CAR) T cell therapy has revolutionized the treatment of several haematological malignancies and is being investigated in...
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Anti-Angiogenic Tyrosine Kinase Inhibitor-Related Toxicities Among Cancer Patients: A Systematic Review and Meta-Analysis
BackgroundTargeting of angiogenesis has become a major therapeutic approach for the treatment of various advanced cancers. There are many unresolved...
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Circulating microRNAs can predict chemotherapy-induced toxicities in patients being treated for primary breast cancer
PurposePrescribing NAC for breast cancer is a pragmatic treatment strategy for several reasons; however, certain patients suffer chemotherapy-induced...
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Body composition and chemotherapy toxicities in breast cancer: a systematic review of the literature
PurposeBreast cancer is the most diagnosed cancer in women with chemotherapy being a common treatment. Toxicities due to chemotherapy can result in...
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The role of dermocosmetics in the management of cancer-related skin toxicities: international expert consensus
Skin toxicities are very common in patients undergoing cancer treatment and have been found to occur with all types of cancer therapeutic...
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Influence of malnutrition according to the glim criteria on the chemotherapy toxicities in patients with advanced lung cancer
BackgroundCancer-associated malnutrition is highly prevalent in advanced lung cancer, and 50% of global cancer-related deaths are attributed to...
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Asparaginase: How to Better Manage Toxicities in Adults
Purpose of ReviewThis review aims to help oncologists who predominantly treat adults better understand and manage asparaginase associated toxicities...
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Hematologic toxicities, sarcopenia, and body composition change in breast cancer patients undergoing neoadjuvant chemotherapy
PurposeEvaluation of body composition and sarcopenia status could provide evidence for more sensitive prediction of chemotherapy toxicities and...
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Life-threatening toxicities upon Pembrolizumab intake: could pharmacokinetics be the bad guy?
PurposeWe report the case of an adult patient diagnosed with Hodgkin’s lymphoma who was scheduled for Pembrolizumab after failure of standard...
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A real-world pharmacovigilance study investigating the toxicities of histone deacetylase inhibitors
Histone deacetylase (HDAC) inhibitors are emerging as promising treatments for hematological malignancies, with potential applications extending to...
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Toxicities, intensive care management, and outcome of chimeric antigen receptor T cells in adults: an update
BackgroundChimeric antigen receptor T cells are a promising new immunotherapy for haematological malignancies. Six CAR-T cells products are currently...
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Evaluation of the additional prophylactic effect of topical steroid ointment to systemic minocycline against anti-epidermal growth factor antibody-induced skin toxicities in metastatic colorectal cancer treatment
BackgroundAnti-epidermal growth factor receptor (EGFR) antibodies often cause skin toxicities. Preemptive skin treatments using systemic antibiotics...
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Risk factor analysis for anti-epidermal growth factor receptor monoclonal antibody–induced skin toxicities in real-world metastatic colorectal cancer treatment
PurposeAnti-epidermal growth factor receptor (anti-EGFR) monoclonal antibodies are effective in treating RAS wild-type metastatic colorectal cancer...
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Cardiovascular Toxicities Associated with Tyrosine Kinase Inhibitors
Purpose of ReviewTo provide a detailed overview of cardiovascular adverse events associated with the use of tyrosine kinase inhibitors across...
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Exploring a multi-disciplinary model of supportive cancer care for monoclonal antibody treatment-related dermatological symptoms
Context and objectivesThe present study examined the perspectives of healthcare providers (HCPs) in designing a multi-disciplinary model of...
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Microbiome-gut-brain axis in cancer treatment-related psychoneurological toxicities and symptoms: a systematic review
PurposeThe microbiome-gut-brain (MGB) axis provides a dynamic model to understand associations between the gut microbiota and psychoneurological...
