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Transformation of Rasch model logits for enhanced interpretability
BackgroundThe Rasch model allows for linear measurement based on ordinal item responses from rating scales commonly used to assess health outcomes....
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Single-cell RNA sequencing of a new transgenic t(8;21) preleukemia mouse model reveals regulatory networks promoting leukemic transformation
T(8;21)(q22;q22), which generates the AML1-ETO fusion oncoprotein, is a common chromosomal abnormality in acute myeloid leukemia (AML) patients....
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A clinical–radiomics model based on noncontrast computed tomography to predict hemorrhagic transformation after stroke by machine learning: a multicenter study
ObjectiveTo build a clinical–radiomics model based on noncontrast computed tomography images to identify the risk of hemorrhagic transformation (HT)...
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Radiomics using non-contrast CT to predict hemorrhagic transformation risk in stroke patients undergoing revascularization
ObjectivesThis study explores whether textural features from initial non-contrast CT scans of infarcted brain tissue are linked to hemorrhagic...
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Prediction of cerebral hemorrhagic transformation after thrombectomy using a deep learning of dual-energy CT
ObjectivesTo develop and validate a deep learning model for predicting hemorrhagic transformation after endovascular thrombectomy using dual-energy...
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Transformation risk and associated survival outcome of marginal zone lymphoma: A nationwide study
Histological transformation into an aggressive B-cell lymphoma indicates a poor survival outcome for patients with indolent marginal zone lymphoma...
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A fully automated and explainable algorithm for predicting malignant transformation in oral epithelial dysplasia
Oral epithelial dysplasia (OED) is a premalignant histopathological diagnosis given to lesions of the oral cavity. Its grading suffers from...
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Digital Transformation in the Control of Neglected Tropical Diseases: A Sco** Review
Purpose of ReviewThere is an increasing interest in the role of digital health in the healthcare industry, focusing on enhancing patient care through...
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Care transformation defined by conditions, mechanisms, and outcomes: a systematic literature review
BackgroundQuality of care is under pressure due to demographic changes (shifting age of the population), epidemiological trends (more chronic...
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Artificial intelligence-driven enhanced skin cancer diagnosis: leveraging convolutional neural networks with discrete wavelet transformation
BackgroundArtificial intelligence (AI) has shown great promise in the field of healthcare as a means of improving the diagnosis of skin cancer. The...
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Facilitators of and barriers to County Behavioral Health System Transformation and Innovation: an interview study
BackgroundInadequate and inequitable access to quality behavioral health services and high costs within the mental health systems are long-standing...
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Bridging the voice of healthcare to digital transformation in practice – a holistic approach
BackgroundDigital transformation is key for healthcare to meet future needs and expectations and compete equally with new actors on the market....
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The digital transformation in pharmacy: embracing online platforms and the cosmeceutical paradigm shift
In the face of rapid technological advancement, the pharmacy sector is undergoing a significant digital transformation. This review explores the...
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Pretreatment parameters associated with hemorrhagic transformation among successfully recanalized medium vessel occlusions
Although pretreatment radiographic biomarkers are well established for hemorrhagic transformation (HT) following successful mechanical thrombectomy...
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Domain transformation using semi-supervised CycleGAN for improving performance of classifying thyroid tissue images
PurposeA large number of research has been conducted on the classification of medical images using deep learning. The thyroid tissue images can be...
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Reduced smooth muscle-fibroblasts transformation potentially decreases intestinal wound healing and colitis-associated cancer in ageing mice
Cancer and impaired tissue wound healing with ageing are closely related to the quality of life of the elderly population. Given the increased...
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RUNX1 mutations mitigate quiescence to promote transformation of hematopoietic progenitors in Fanconi anemia
Many inherited bone marrow failure syndromes (IBMFSs) present a high risk of transformation to myelodysplastic syndrome (MDS) and acute myeloid...
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The gut microbiome modulates the transformation of microglial subtypes
Clinical and animal studies have shown that gut microbiome disturbances can affect neural function and behaviors via the microbiota–gut–brain axis,...
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PARs in the inflammation-cancer transformation of CRC
Colorectal cancer (CRC) is one of the common malignancies with a global trend of increasing incidence and mortality. There is an urgent need to...
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Metabolomics analysis of serum metabolites during endometrial transformation: association with recurrent implantation failure in hormonal replacement therapy-frozen embryo transfers cycles
PurposeThe purpose of this study was to investigate alterations in serum metabolites during endometrial transformation and possible associations...
