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Imaging of aqueous outflow in health and glaucoma. Justifying the re-direction of aqueous
A wave of less invasive surgical options that target or bypass the conventional aqueous outflow system has been incorporated into routine clinical...
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RNA-seq analysis of human trabecular endothelial cells after treatment with timolol maleate
PurposeTimolol maleate (timolol), a β-receptor blocker, reduces intraocular pressure by decreasing aqueous humor production. Timolol reportedly also...
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VEGF-A-induced changes in distal outflow tract structure and function
PurposeTo investigate changes in distal outflow tract vessels caused by VEGF-A and their impact on outflow.
MethodsWe compared VEGF-A perfused...
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Double trouble - dual outflow tract obstruction in congenital heart disease: a case report
BackgroundDouble chambered right ventricle is a rare congenital heart disease that is characterised by the presence of an anomalous muscle bundle...
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Five-Year Outcomes of Single Trabecular Microbypass Stent (iStent®) Implantation with Phacoemulsification in Korean Patients
IntroductionThis study reports the long-term intraocular pressure (IOP)-lowering efficacy and safety of a single trabecular microbypass stent (iStent
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The effect of uneventful cataract surgery on Schlemm’s canal and the trabecular meshwork in cases with pseudoexfoliation
PurposeTo evaluate the effect of uneventful cataract surgery on Schlemm’s canal (SC) and the trabecular meshwork (TM) in cases with pseudoexfoliation...
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Ten-Year Effectiveness and Safety of Trabecular Micro-Bypass Stent Implantation with Cataract Surgery in Patients with Glaucoma or Ocular Hypertension
IntroductionThis study evaluated 10-year results of implanting one iStent trabecular micro-bypass stent during cataract surgery in eyes with...
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7-Year Efficacy and Safety of iStent inject Trabecular Micro-Bypass in Combined and Standalone Usage
IntroductionThis study evaluated 7-year effectiveness and safety of second-generation trabecular micro-bypass implantation (iStent inject ) either in...
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Efficacy and Safety of Pairing iStent Inject Trabecular Micro-Bypass and iAccess Precision Blade Goniotomy in Patients with Open-Angle Glaucoma
IntroductionThis study evaluated efficacy and safety of implanting two second-generation trabecular micro-bypass stents (iStent inject /iStent inject ...
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Paeoniflorin alleviates TGF-β2-mediated extracellular matrix remodeling and oxidative stress in human trabecular meshwork cells
BackgroundThe multifunctional profibrotic cytokine transforming growth factor-beta2 (TGF-β2) is implicated in the pathophysiology of primary open...
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Corneal endothelial cell loss after EX-PRESS surgery depends on site of insertion, cornea or trabecular meshwork
PurposePreviously, we reported that the Ex-press® shunt (EXP) was associated with more rapid reduction in corneal endothelial cells when inserted...
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The relation of right ventricular outflow tract measurements with in-hospital clinical outcomes after tricuspid valve surgery
Right ventricular (RV) function is a determining factor for clinical outcomes in patients undergoing tricuspid valve surgery (TVS). Our aim was to...
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Comparing the trabecular outflow by the response to topical pilocarpine in patients with and without glaucoma filtering surgery
PurposeTo compare the trabecular outflow by the response to topical pilocarpine administration in patients with and without prior glaucoma filtering...
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Comparative Effectiveness and Safety of Two Different Trabecular MIGS Devices With and Without Ab Interno Canaloplasty in Patients with Primary Open-Angle Glaucoma
IntroductionThis study compared outcomes of the iStent inject trabecular micro-bypass system versus the Hydrus Microstent in patients with primary...
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Canaloplasty and trabeculotomy with the OMNI® surgical system in OAG with prior trabecular microbypass stenting
PurposeEvaluate effectiveness and safety outcomes for patients treated with canaloplasty and trabeculotomy previously treated with a trabecular...
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The effect of ET1-CTGF mediated pathway on the accumulation of extracellular matrix in the trabecular meshwork and its contribution to the increase in IOP
PurposeTo investigate the effect of endothelin-1 (ET-1) in excessive accumulation of extracellular matrix (ECM) of the trabecular meshwork (TM) and...
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Sampling trabecular meshwork using TrabEx+
BackgroundTo report sampling of the trabecular meshwork using the TrabEx+ (MicroSurgical Technology, Redmond, Washington, USA) device in ab interno...
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Aqueous humour outflow imaging: seeing is believing
Elevated intraocular pressure (IOP) is the primary risk factor for blindness in glaucoma. IOP is determined by many factors including aqueous humour...
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Relationship of degrees of gonioscopy assisted transluminal trabeculotomy and trabecular shelf to success using a marker suture technique
ObjectiveTo evaluate the safety and efficacy of gonioscopy-assisted transluminal trabeculotomy (GATT) using a marker suture which could be a viable...
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Comparison of outflow facility before and after the microhook ab interno trabeculotomy
PurposesTo elucidate the mechanism of intraocular pressure (IOP) reduction by microhook ab interno trabeculotomy (μLOT), the aqueous humour outflow...
