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Lay healthcare worker financial toxicity intervention: a pilot financial toxicity screening and referral program
PurposeFinancial toxicity is a source of significant distress for patients with urologic cancers, yet few studies have addressed financial burden in...
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Cardiovascular toxicity of checkpoint inhibitors: review of associated toxicity and design of the Spanish Immunotherapy Registry of Cardiovascular Toxicity
Immune checkpoint inhibitors (ICI) have changed the prognosis of many tumors. However, concerning associated cardiotoxicity has been reported. Little...
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Financial Toxicity
Despite universal health insurance and a well-established social security system in Germany, it is possible that cancer survivors will experience...
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Toxicity in Older Patients with Cancer Receiving Immunotherapy: An Observational Study
BackgroundCheckpoint inhibition has emerged as an effective treatment strategy for a variety of cancers, including in older adults. However, older...
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Evolution of predictive risk factor analysis for chemotherapy-related toxicity
The causes of variation in toxicity to the same treatment regimen among seemingly similar patients remain largely unknown. There was tremendous...
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Reporting time toxicity in prospective cancer clinical trials: A sco** review
PurposeThis review aimed to assess the measurement and reporting of time toxicity (i.e., time spent receiving care) within prospective oncologic...
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Comprehensive geriatric assessment predicts radiation-induced acute toxicity in prostate cancer patients
PurposeThe purpose of the present prospective study was to evaluate the significance of geriatric conditions measured by a comprehensive geriatric...
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Body composition measures as a determinant of Alpelisib related toxicity
BackgroundBody composition has emerged as an important prognostic factor in patients treated with cancer. Severe depletion of skeletal muscle,...
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Characterizing Utilization and Outcomes of Digoxin Immune Fab for Digoxin Toxicity
BackgroundDigoxin is a widely prescribed drug for congestive heart failure and atrial fibrillation. Digoxin has a narrow therapeutic index and...
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Factors associated with early hydroxychloroquine-induced retinal toxicity in patients with systemic lupus erythematosus
PurposeHydroxychloroquine is currently recommended for the treatment of systemic lupus erythematosus (SLE), but it can cause irreversible retinal...
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A prediction model for severe hematological toxicity of BTK inhibitors
Bruton’s tyrosine kinase inhibitor (BTKi) has revolutionized the treatment of B-cell lymphomas. However, BTKi-related hematological toxicity hinders...
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Characterization of time toxicity in older patients with metastatic breast cancer
PurposeRecognizing that receiving healthcare can be time intensive and burdensome, time toxicity has been conceptualized as the time spent by...
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Financial toxicity among cancer survivors: a conceptual model based on a feedback perspective
PurposeExperiencing financial toxicity following a cancer diagnosis is a circular and complex process. We investigate the circular causal mechanisms...
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Using maximum plasma concentration (Cmax) to personalize taxane treatment and reduce toxicity
Taxanes are a widely used class of anticancer agents that play a vital role in the treatment of a variety of cancers. However, toxicity remains a...
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CAR-T Cell Therapy: the Efficacy and Toxicity Balance
Purpose of ReviewChimeric antigen receptor (CAR) T cell therapy is an immunotherapy that has resulted in tremendous progress in the treatment of...
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Pulmonary Toxicity Associated with Immune Checkpoint Inhibitors-Based Therapy: Current Perspectives and Future Directions
Immune checkpoint inhibitors (ICIs) have shown efficacy in tumor therapy. However, the risk of pulmonary toxicity from ICI-based treatment regimens...
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Ivabradine toxicity: a case report
BackgroundWe describe a case of symptomatic bradycardia resulting from ivabradine toxicity by measurement of ivabradine levels, of which there are...
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Experiences of financial toxicity among caregivers of cancer patients: a meta-synthesis of qualitative studies
ObjectivesThe purpose of this study was to explore the experience of financial toxicity among caregivers of cancer patients and to provide...
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Toxicity of dose-escalated radiotherapy up to 84 Gy for prostate cancer
PurposeThe outcome of radiotherapy (RT) for prostate cancer (PCA) depends on the delivered dose. While the evidence for dose-escalated RT up to...
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Effectiveness and toxicity of five-fraction prone accelerated partial breast irradiation
PurposeOur institution was an early adopter of 5-fraction accelerated partial breast irradiation (ABPI) to treat women with early-stage breast...
