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Topiramate Utilization After Phentermine/Topiramate Approval for Obesity Management: Risk Minimization in the Era of Drug Repurposing
IntroductionThe US FDA required a Risk Evaluation and Mitigation Strategy (REMS) for phentermine/topiramate, an anti-obesity medication, to prevent...
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Narrative Review of Topiramate: Clinical Uses and Pharmacological Considerations
Due to the diverse mechanisms of action of antiseizure drugs, there has been a rise in prescriptions of these drugs for non-epileptic pathologies....
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Phentermine/Topiramate: Pediatric First Approval
Phentermine/topiramate extended-release capsule (Qsymia ® ) is a fixed-dose combination of phentermine and topiramate, which is being developed by...
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Examining the molecular mechanisms of topiramate in alleviating insulin resistance: A study on C2C12 myocytes and 3T3L-1 adipocytes
PurposeMigraine, a severely debilitating condition, may be effectively managed with topiramate, known for its migraine prevention and weight loss...
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Carbonation and Sweet Taste Dysgeusia with Topiramate Therapy for Migraine Prevention Treatment: a Case Report
Migraine is a common disorder with a reported prevalence of up to 12% in the European general population. It has been shown to cause a reduction in...
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European Headache Federation (EHF) critical reappraisal and meta-analysis of oral drugs in migraine prevention – part 3: topiramate
ObjectiveTopiramate is a repurposed first-line treatment for migraine prophylaxis. The aim of this systematic review and meta-analysis is to...
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Comparison between the effectiveness of three prophylactic drugs for vestibular migraine; cinnarizine, propranolol, and topiramate: prospective study
BackgroundVestibular migraine (VM) is considered one of the most common causes of episodic vertigo. Acute attacks may interfere or hinder daily...
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Brivaracetam and topiramate serum levels during pregnancy and delivery: a case report and a review of literature
BackgroundAn increasing use of newer antiseizure medication (ASM) such as SV2A ligand brivaracetam is observed. However, data on newer antiseizure...
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Erenumab versus topiramate: post hoc efficacy analysis from the HER-MES study
ObjectiveHER-MES was the first head-to-head, phase 4 trial to assess the tolerability and effectiveness of erenumab against standard of care...
