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Tocotrienol-rich fraction reduces retinal inflammation and angiogenesis in rats with streptozotocin-induced diabetes
BackgroundDiabetic retinopathy (DR) is the second commonest microvascular complication of diabetes mellitus. It is characterized by chronic...
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Effect of defatted rice bran supplementation on metabolic parameters and inflammatory status in overweight/obese adults with hypercholesterolemia: a randomized, placebo-controlled intervention
BackgroundDefatted rice bran (DRB) is a byproduct of rice bran oil production rich in fiber, protein, and antioxidant compounds that may confer...
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Atypical retinopathy in ataxia with vitamin E deficiency: report of a sibship
Typical retinitis pigmentosa (RP) may not be the only retinal phenotype encountered in ataxia with vitamin E deficiency (AVED). The following short...
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The effect of palm oil-derived tocotrienol-rich fraction in preserving normal retinal vascular diameter in streptozotocin-induced diabetic rats
PurposeAngiogenesis in diabetic retinopathy (DR) is associated with increased retinal expression of angiopoietin-2 (Ang-2) and protein kinase C...
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Molecular Aspects in the Potential of Vitamins and Supplements for Treating Diabetic Neuropathy
Purpose of ReviewTo discuss and provide evidence-based data on dietary supplements as part of treating diabetic neuropathy
Recent Findings ...
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Investigation of frailty markers including a novel biomarker panel in emergency laparotomy: protocol of a prospective cohort study
BackgroundEmergency laparotomy (EmLAP) is one of the commonest emergency operations performed in the United Kingdom (approximately 30, 000...
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Effect of bovine milk fat-based infant formulae on microbiota, metabolites and stool parameters in healthy term infants in a randomized, crossover, placebo-controlled trial
BackgroundNatural enrichment of sn-2 palmitate content of infant formulae by using bovine milk fat is known to reduce formation of faecal fatty acid...
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The impact of the Mediterranean diet on immune function in older adults
Diet is one of the lifestyle factors that is most amenable to intervention, and has a substantial effect on the potential for successful aging and...
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Eosinophil extracellular traps in asthma: implications for pathogenesis and therapy
Asthma is a common, chronic inflammatory disease of the airways that affects millions of people worldwide and is associated with significant...
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Dietary vitamin intake and cancer risk in patients with chronic kidney disease: results from the National Health and Nutrition Examination Survey (2007–2018)
PurposeThe relationship between vitamin intake and cancer risk in the chronic kidney disease (CKD) population is unknown. For this reason, we...
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Serum metabolism alteration behind different etiology, diagnosis, and prognosis of disorders of consciousness
BackgroundPatients with disorders of consciousness (DoC) exhibit varied revival outcomes based on different etiologies and diagnoses, the mechanisms...
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Vitamin E and Alzheimer’s disease: the mediating role of cellular aging
BackgroundVitamin E represents a potent antioxidant and anti-inflammatory system, playing a role in Alzheimer’s disease (AD). Different plasma...
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Metabolomic analysis of serum alpha-tocopherol among men in the Alpha-Tocopherol, Beta-Carotene Cancer Prevention (ATBC) Study
Background/ObjectivesThe role of vitamin E in chronic disease risk remains incompletely understood, particularly in an un-supplemented state, and...
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Associations between food groups and liver cancer: a systematic review and meta-analysis of observational studies
ContextDiet is emerging as a modifiable component of lifestyle for influencing the incidence of liver cancer.
ObjectiveTo investigate and quantify...
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Effect of surgery on oxidative stress and endogenous tocopherol concentrations in juvenile female dogs
BackgroundSurgery such as ovariectomy causes an inflammatory and oxidative stress. This study was designed to evaluate endogenous tocopherol levels...
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Vitamins as regulators of calcium-containing kidney stones — new perspectives on the role of the gut microbiome
Calcium-based kidney stone disease is a highly prevalent and morbid condition, with an often complicated and multifactorial aetiology. An abundance...
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Koetjapic acid: unveiling its potential as a saviour in the realm of biological and medicinal properties, with a focus on anticancer mechanism of action
Scientists have been compelled to search for alternative treatments due to the increasing prevalence of chemoresistance as well as the agonising and...
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The role of infections and inflammation in schizophrenia: review of the evidence
BackgroundSchizophrenia is a severe mental illness affecting approximately 1% of the population worldwide. While its exact causes remain unknown,...
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Effects of Royal Jelly and Tocotrienol Rich Fraction in obesity treatment of calorie-restricted obese rats: a focus on white fat browning properties and thermogenic capacity
BackgroundObesity has reached an alarming rate worldwide. Promoting thermogenesis via increasing the function of brown adipose tissue (BAT) or white...
