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Prevalence of thyroid carcinoma in nodules with thy 3 cytology: the role of preoperative ultrasonography and strain elastography
BackgroundFine needle aspiration (FNA) cytology, the gold standard in assessing thyroid nodules, is limited by its inability to determine the true...
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Low dose post-transplant cyclophosphamide and sirolimus induce mixed chimerism with CTLA4-Ig or lymphocyte depletion in an MHC-mismatched murine allotransplantation model
Allogeneic hematopoietic cell transplantation (allo-HCT) offers a curative option for patients with certain non-malignant hematological diseases....
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Thyrogrit, supplemented with a sub-optimal dose of levothyroxine, restores thyroid function in rat model of propylthiouracil-induced hypothyroidism
BackgroundHypothyroidism is a common endocrine ailment, whose current standard of care is hormonal replacement therapy with levothyroxine (LT4)....
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Activated CD90/Thy-1 fibroblasts co-express the Δ133p53β isoform and are associated with highly inflamed rheumatoid arthritis
BackgroundThe p53 isoform Δ133p53β is known to be associated with cancers driven by inflammation. Many of the features associated with the...
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Thy-1 predicts poor prognosis and is associated with self-renewal in ovarian cancer
BackgroundOvarian cancer is the leading cause of gynecologic cancer death in the United States despite effective first-line systemic chemotherapy....
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Assessment of quality of life in thyroid cancer patients using the EORTC thyroid-specific questionnaire: a prospective cross-sectional study
BackgroundMany studies on the quality of life (QoL) among the thyroid cancer survivors have shown conflicting results. This may be since many of...
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Causal Relationship Between Basal Metabolic Rate and Alzheimer’s Disease: A Bidirectional Two-sample Mendelian Randomization Study
IntroductionObjective observational studies have shown that basal metabolic rate (BMR) decreases in patients with Alzheimer’s disease (AD), but the...
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Is repeat fine needle aspiration required in thyroid nodules with initial benign cytology? Results from a large Irish series
BackgroundFine needle aspiration (FNA) cytology is the preferred method for assessing thyroid nodules for malignancy. Concern remains about the rate...
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Long-term survival with mixed chimerism in patients with AML and MDS transplanted after conditioning with targeted busulfan, fludarabine, and thymoglobulin
We evaluated long-term outcome in 40 patients with MDS or AML, transplanted from related or unrelated donors following conditioning with targeted...
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Thy-1 depletion and integrin β3 upregulation-mediated PI3K-Akt-mTOR pathway activation inhibits lung fibroblast autophagy in lipopolysaccharide-induced pulmonary fibrosis
Lipopolysaccharide (LPS)-induced autophagy inhibition in lung fibroblasts is closely associated with the activation of the phosphatidylinositol...
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Comparison of a thymine challenge test and endogenous uracil–dihydrouracil levels for assessment of fluoropyrimidine toxicity risk
PurposeStandard dosages of fluoropyrimidine chemotherapy result in severe toxicity in a substantial proportion of patients, however, routine...
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Causal relationship between basal metabolic rate and intervertebral disc degeneration: a Mendelian randomization study
BackgroundThe role of basal metabolic rate (BMR) in intervertebral disc degeneration (IVDD) is still uncertain. To address this gap, we conducted a...
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Platelet-rich plasma therapy in erectile dysfunction and Peyronie’s disease: a systematic review of the literature
PurposePlatelet-rich plasma (PRP) as a regenerative therapy has gained interest in the field of andrology for the treatment of erectile dysfunction...
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Prediction of liver-related events in patients with compensated HBV-induced cirrhosis receiving antiviral therapy
Background and aimsMany models have been developed to predict liver-related events (LRE) in chronic hepatitis B, few focused on compensated...
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Do pentraxin 3 and neural pentraxin 2 have different facet function in hepatocellular carcinoma?
The long pentraxin (PTX) 3 and the neuronal pentraxin (NPTX) 2 has been found to exert pleiotropic roles in cancers due to their action in...
