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Real-World Effectiveness of a Third Dose of mRNA-1273 Versus BNT162b2 on Inpatient and Medically Attended COVID-19 Among Immunocompromised US Adults
IntroductionRecent data have shown elevated infection rates in several subpopulations at risk of SARS-CoV-2 infection and COVID-19, including...
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Efficacy of second and third lines of treatment in advanced soft tissue sarcomas: a real-world study
BackgroundSoft tissue sarcomas (STSs) are an uncommon and heterogeneous group of tumours. Several drugs and combinations have been used in clinical...
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Real-World Cost Effectiveness of a Policy of KRAS Testing to Inform Cetuximab or Panitumumab for Third-Line Therapy of Metastatic Colorectal Cancer in British Columbia, Canada
BackgroundCetuximab and panitumumab, two anti-EGFR therapies, are widely used for third-line therapy of metastatic colorectal cancer (mCRC) with...
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Real-world effectiveness of third- or later-line treatment in Japanese patients with HER2-positive, unresectable, recurrent or metastatic gastric cancer: a retrospective observational study
BackgroundReal-world evidence on the preference for and effectiveness of third- or later-line (3L +) monotherapy for HER2-positive gastric cancer is...
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From real world data to real world evidence to improve outcomes in neuro-ophthalmology
Real-world data (RWD) can be defined as all data generated during routine clinical care. This includes electronic health records, disease-specific...
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Real-world Management of CML: Outcomes and Treatment Patterns
Purpose of ReviewChronic myeloid leukemia (CML) is a disease that previously signified a poor prognosis, but treatment options and outcomes have...
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Real-world experience with filgotinib for rheumatoid arthritis in Germany
BackgroundReal-world data for filgotinib, a Janus kinase (JAK)1 inhibitor, are limited in patients with rheumatoid arthritis (RA).
Objectives ...
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Real-world efficacy and safety of anlotinib as third- or further-line treatment in refractory small cell lung cancer
PurposeAs a novel antiangiogenic multi-target tyrosine kinase inhibitor recently approved in China, anlotinib has exhibited promising anticancer...
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Evaluation of Blood Loss in Third-Generation Internal Ultrasound-Assisted Liposuction
BackgroundIn large-volume liposuction procedures, one of the most important limitations of total lipoaspirate volume is blood loss. In this study, we...
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Prevalence and Pattern of Impacted Mandibular Third Molar: An Institution-Based Retrospective Study
IntroductionClassifications of impaction based on panoramic radiographs such as the ones of Pell and Gregory and Winter are essential to allow a...
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The current state of anesthesia safety in a third world country: a cross-sectional survey among anesthesia providers in Ethiopia
BackgroundImproving patient safety during anesthesia and surgery becomes a major global public health issue due to the increasing in surgical burden....
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Third-child fertility intention and its socioeconomic factors among women aged 20–34 years in China
BackgroundThe low birth rates and rapid population aging has drawn considerable attention from scholars and policymakers in China and around the...
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Virological outcomes of third-line antiretroviral therapy in a global context: a systematic reviews and meta-analysis
BackgroundDespite remarkable progress, HIV’s influence on global health remains firm, demanding continued attention. Understanding the effectiveness...
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Harnessing the Potential of Real-World Evidence in the Treatment of Colorectal Cancer: Where Do We Stand?
Treatment guidelines for colorectal cancer (CRC) are primarily based on the results of randomized clinical trials (RCTs), the gold standard...
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The impact of COVID-19 on the intention of third-child in China: an empirical analysis based on survey data
BackgroundAgainst the grim background of declining intention to have children, the ravages of COVID-19 have pushed China and the world into a more...
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Applying the World Stroke Organization roadmap in planning a model for stroke service implementation in Matrouh Governorate-Egypt: a World Stroke Organization young future stroke leaders’ analytical study
BackgroundThe global incidence of stroke is on the rise, primarily due to an increase in the aging population and the prevalence of vascular risk...
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Diagnosis of sepsis in the emergency department: a real-world analysis from Lombardy, Italy
Early identification of sepsis is particularly important in the emergency department (ED). However, data on the diagnosis of sepsis in the ED are...
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Health economic analysis of third-line interventions in diffuse large B-cell lymphomas in Germany: applying the efficiency frontier
BackgroundIn the past decades, highly innovative treatments in the field of diffuse large B-cell lymphoma (DLBCL) became available in clinical...
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SARS-CoV-2 vaccination and multiple sclerosis: a large multicentric study on relapse risk after the third booster dose
BackgroundCOVID-19 vaccines have been recommended to people with multiple sclerosis (pwMS) and, to ensure durable immunity, a third booster dose has...
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Distribution of nursing workforce in the world using Gini coefficient
IntroductionUnequal Access to human resources for health, reduces access to healthcare services, worsens the quality of services and reduces health...
