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  1. The relationship between imaging features, therapeutic response, and overall survival in pediatric diffuse intrinsic pontine glioma

    We aimed to evaluate the relationship between imaging features, therapeutic responses (comparative cross-product and volumetric measurements), and...

    **aojun Yu, Mingyao Lai, ... Linbo Cai in Neurosurgical Review
    Article Open access 10 May 2024
  2. Therapeutic targets and biomarkers of tumor immunotherapy: response versus non-response

    Cancers are highly complex diseases that are characterized by not only the overgrowth of malignant cells but also an altered immune response. The...

    Dong-Rui Wang, **an-Lin Wu, Ying-Li Sun in Signal Transduction and Targeted Therapy
    Article Open access 19 September 2022
  3. Histopathology images-based deep learning prediction of prognosis and therapeutic response in small cell lung cancer

    Small cell lung cancer (SCLC) is a highly aggressive subtype of lung cancer characterized by rapid tumor growth and early metastasis. Accurate...

    Yibo Zhang, Zijian Yang, ... Meng Zhou in npj Digital Medicine
    Article Open access 18 January 2024
  4. Reclassification of therapeutic response of unresectable hepatocellular carcinoma to anti-angiogenic therapy and immunotherapy using alpha RECIST

    Objectives

    To assess the therapeutic response of HCC to antiangiogenic therapy plus immunotherapy by integrating RECIST 1.1 and alpha-fetoprotein...

    Ying Xu, Yi Yang, ... Hong Zhao in European Radiology
    Article 23 September 2023
  5. Changes in therapeutic response, ocular manifestations of Graves’ orbitopathy and quality of life during the first year after orbital radiotherapy

    Purpose

    The aim of our study was to assess the changes in the therapeutic response, ocular manifestations of GO and quality of life during the first...

    Mariya Asenova Stoynova, Alexander Dimitrov Shinkov, ... Roussanka Dimitrova Kovatcheva in International Ophthalmology
    Article 10 August 2023
  6. Serum uric acid predicts therapeutic response to midodrine hydrochloride in children with vasovagal syncope: a pilot study

    Abstract

    Serum uric acid (UA) level has been proven to be related to several cardiovascular and metabolic diseases. In the present study, we examined...

    **aojuan Du, Xueying Li, ... Hongfang ** in European Journal of Pediatrics
    Article Open access 31 October 2023
  7. Targeting CD73 increases therapeutic response to immunogenic chemotherapy by promoting dendritic cell maturation

    The CD39-CD73–adenosinergic pathway converts adenosine triphosphate (ATP) to adenosine for inhibiting anti-tumor immune responses. Therefore,...

    Yun-Shan Lin, Shu-Fen Chiang, ... Kevin Chih-Yang Huang in Cancer Immunology, Immunotherapy
    Article 07 March 2023
  8. Effect of direct therapeutic ultrasound exposure of ovaries on histopathology, inflammatory response, and oxidative stress in dogs

    Background

    This research was designed to evaluate the effects of therapeutic ultrasound waves on ovarian germinal tissue and inflammatory cytokines...

    Arian Rajabi, Asghar Mogheiseh, ... Amin Bigham-Sadegh in BMC Veterinary Research
    Article Open access 20 July 2023
  9. Activation of STING by the novel liposomal TLC388 enhances the therapeutic response to anti-PD-1 antibodies in combination with radiotherapy

    Current immune checkpoint inhibiters (ICIs) have contrasting clinical results in poorly immunogenic cancers such as microsatellite-stable colorectal...

    Jhen-Yu Chen, Po-Yu Lin, ... Kevin Chih-Yang Huang in Cancer Immunology, Immunotherapy
    Article Open access 02 April 2024
  10. Early assessment of the pharmacokinetic and pharmacodynamic effects following acetylsalicylic acid loading: toward a definition for acute therapeutic response

    Despite decades of investigations, the optimal assessment of the “therapeutic response” to early after loading dose of acetylsalicylic acid (ASA)...

    Paul A. Gurbel, Kevin P. Bliden, ... Udaya S. Tantry in Journal of Thrombosis and Thrombolysis
    Article Open access 08 December 2023
  11. Therapeutic hypothermia modulates the neurogenic response of the newborn piglet subventricular zone after hypoxia-ischemia

    Background

    Neuroprotection combined with neuroregeneration may be critical for optimizing functional recovery in neonatal encephalopathy. To...

    Daniel Alonso-Alconada, Pierre Gressens, ... Nicola J. Robertson in Pediatric Research
    Article Open access 12 August 2023
  12. Pretreatment Pan-Immune-Inflammation Value (PIV) in Predicting Therapeutic Response and Clinical Outcomes of Neoadjuvant Immunochemotherapy for Esophageal Squamous Cell Carcinoma

    Purpose

    The pan-immune-inflammation value (PIV), which reflects the balance between the host immune and inflammatory status, is a readily available...

    Jifeng Feng, Liang Wang, ... **angdong Cheng in Annals of Surgical Oncology
    Article 14 October 2023
  13. Integrated dose–response metabolomics with therapeutic effects and adverse reactions may demystify the dosage of traditional Chinese medicine

    Background

    Traditional Chinese medicine (TCM) has been used to treat various diseases for thousands of years. However, the uncertainty of dosage as...

    Yan-Yan Chen, Jia-Qian Chen, ... **-Ao Duan in Chinese Medicine
    Article Open access 19 November 2022
  14. Therapeutic Response After Immunosuppressive Drug Prescription in Non-infectious Uveitis: A Survival Analysis

    Introduction

    To identify factors affecting the response rate to immunosuppressive drugs (ISDs) in patients with non-infectious uveitis (NIU).

    ...
    Alejandro Gómez-Gómez, Alfredo Madrid-Garcia, ... Luis Rodriguez-Rodriguez in Ophthalmology and Therapy
    Article Open access 20 October 2022
  15. Evaluation of 18F-FAPI-04 Imaging in Assessing the Therapeutic Response of Rheumatoid Arthritis

    Purpose

    Fibroblast activating protein (FAP) is highly expressed in the synovial tissues of rheumatoid arthritis (RA) patients. The aim of this study...

    Qingyun Zhang, Xuehong Lin, ... **xiang Han in Molecular Imaging and Biology
    Article 05 April 2023
  16. Molecular subtypes of lung adenocarcinoma patients for prognosis and therapeutic response prediction with machine learning on 13 programmed cell death patterns

    Background

    Lung adenocarcinoma (LUAD) seriously threatens people’s health worldwide. Programmed cell death (PCD) plays a critical role in regulating...

    Qin Wei, **aoyu Jiang, ... Pengju Zhang in Journal of Cancer Research and Clinical Oncology
    Article 28 June 2023
  17. Usefulness of circulating EPAC1 as biomarkers of therapeutic response to GLP-1 receptor agonists

    Aims

    The response to Glucagon-like peptide-1 receptor agonists (GLP-1RAs) is highly varia-ble among patients. Thus, the identification of predictive...

    Cristina Hernández, Fernando Gómez-Peralta, ... Rafael Simó in Acta Diabetologica
    Article 04 August 2022
  18. Disulfidptosis-Related lncRNA for the Establishment of Novel Prognostic Signature and Therapeutic Response Prediction to Endometrial Cancer

    Disulfidptosis, a newly discovered cellular death mechanism initiated by disulfide stress, features elevated expression of SLC7A11 and restricted...

    Shan** Shi, **aojian Tang, Hua Liu in Reproductive Sciences
    Article 25 October 2023
  19. Identification of genomic drivers for the therapeutic response of Cabozantinib in patients with metastatic renal cell carcinoma

    Purpose

    Cabozantinib (CAB) as monotherapy or in combination with immune checkpoint inhibitors is used for systemic treatment of metastatic renal cell...

    Angelika Borkowetz, Ulrich Sommer, ... Christian Thomas in World Journal of Urology
    Article Open access 22 February 2024
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