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Specificity of serological screening tests and reference laboratory tests to diagnose gambiense human African trypanosomiasis: a prospective clinical performance study
BackgroundSerological screening tests play a crucial role to diagnose gambiense human African trypanosomiasis (gHAT). Presently, they preselect...
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Estimating sensitivity and specificity of diagnostic tests using latent class models that account for conditional dependence between tests: a simulation study
BackgroundLatent class models are increasingly used to estimate the sensitivity and specificity of diagnostic tests in the absence of a gold...
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GH provocative tests stimulate the growth in children with idiopathic short stature
ContextGrowth hormone (GH) deficiency in a child with short stature is diagnosed by GH secretion provocative tests. When the test response is...
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Respiratory Exposure Tests in Aspirin Exacerbated Respiratory Disease
Purpose of reviewControlled oral provocation test with aspirin is considered the “gold standard” for diagnosing hypersensitivity to NSAIDs...
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Lung Function Tests in Infants and Children
Lung function testing is an essential modality of investigation in children as it provides objective evidence of lung disease/health. With advances...
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An update on tests used for intraoperative monitoring of cognition during awake craniotomy
PurposeMap** higher-order cognitive functions during awake brain surgery is important for cognitive preservation which is related to postoperative...
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MAFLD in adults: non-invasive tests for diagnosis and monitoring of MAFLD
Metabolic dysfunction-associated fatty liver disease (MAFLD) is the liver manifestation of a metabolic syndrome and is highly prevalent in the...
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Serum and 24-hour urinary tests cost-effectiveness in stone formers
ObjectiveTo assess the routine serum and 24-hour urine tests proficiency in diagnosing the baseline metabolic abnormality of kidney stone formers.
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Clinical Utility of Sperm Function Tests in Predicting Male Fertility: A Systematic Review
Routine semen analysis provides considerable information regarding sperm parameters; however, it is not solely adequate to predict male fertility...
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Modified thromboelastometric tests provide improved sensitivity and specificity to direct oral anticoagulants compared to standard thromboelastometric tests in-vitro
BackgroundThe detection of direct oral anticoagulants (DOACs) is still challenging but important in emergency patients. We recently demonstrated that...
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Detection of sensitivity and vestigiality of presumptive tests for swabbed blood stains
It is a common practice in forensic casework to use presumptive tests for blood stains before DNA extraction and testing. Stains are usually swabbed...
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Use of Epicutaneous Tests in the Study of Drug Allergy
Purpose of ReviewEpicutaneous or patch tests (PT) are a common diagnostic tool in the study of adverse skin reactions related to the topical or...
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Modelling the Cost-Effectiveness of Diagnostic Tests
Diagnostic tests are used to determine whether a disease or condition is present or absent in a patient, who will typically be suspected of having...
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Acceptable performance of blood biomarker tests of amyloid pathology — recommendations from the Global CEO Initiative on Alzheimer’s Disease
Anti-amyloid treatments for early symptomatic Alzheimer disease have recently become clinically available in some countries, which has greatly...
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Augmented reality versus standard tests to assess cognition and function in early Alzheimer’s disease
Augmented reality (AR) apps, in which the virtual and real world are combined, can recreate instrumental activities of daily living (IADL) and are...
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A retrospective study of accuracy and usefulness of electrophysiological exercise tests
ObjectivesThis study aimed to determine the usefulness of electrophysiological exercise tests. The significance of slightly abnormal exercise tests...
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Performance of intraoperative neurocognitive tests during awake surgery for patients with diffuse low-grade glioma
Despite great advancements and the diffusion of awake surgery for brain tumors, the literature shows that the tests applied during the procedure are...
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Exploring pre-MRI imaging tests: patient survey reveals potential implications for healthcare efficiency in Israel
BackgroundMedical imaging tests are vital in healthcare but can be costly, impacting national health expenditures. Magnetic resonance imaging (MRI)...
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Reliability and measurement error of sensorimotor tests in patients with neck pain: a systematic review
BackgroundNeck pain is one of the leading causes of years lived with disability, and approximately half of people with neck pain experience recurrent...
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Integration of the expanded disability status scale with ambulation, visual and cognitive tests
IntroductionThe Expanded Disability Status Scale (EDSS) is usually calculated through a neurological examination with self-reported performance. This...