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Lymphoproliferative disorder during temozolomide therapy; a representative case of a formidable complication and management challenges
BackgroundLymphoproliferative disorder represents a heterogeneous clinicopathological spectrum characterized by uncontrolled proliferation of...
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Cordycepin improves sensitivity to temozolomide in glioblastoma cells by down-regulating MYC
PurposeGlioblastoma is one of the malignant tumors with poor prognosis and no effective treatment is available at present.
MethodsTo study the...
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A combined analysis of two prospective randomised studies exploring the impact of extended post-radiation temozolomide on survival outcomes in newly diagnosed glioblastoma
PurposeThe optimal duration of post-radiation temozolomide in newly diagnosed glioblastoma remains unclear, with no published phase III randomised...
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Patterns, predictors and prognostic relevance of high-grade hematotoxicity after temozolomide or temozolomide-lomustine in the CeTeG/NOA-09 trial
PurposeIn the randomized phase III trial CeTeG/NOA-09, temozolomide (TMZ)/lomustine (CCNU) combination therapy was superior to TMZ in newly diagnosed...