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Participant attention on the intervention target during repetitive passive movement improved spinal reciprocal inhibition enhancement and joint movement function
This study aimed to evaluate the effects of the participant’s attention target during repetitive passive movement (RPM) intervention on reciprocal...
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Sacroiliac Joint Denervation—A Novel Approach to Target Sacral Lateral Branches: A Practical Approach
IntroductionSacroiliac joint (SIJ) pain is a relatively common cause of low back pain. Percutaneous radiofrequency (RF) techniques for SIJ are...
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Achieving osteoporosis treat-to-target goals with teriparatide or alendronate: sub-analysis of Japanese Osteoporosis Intervention Trial-05 (JOINT-05)
IntroductionThe purpose of this study was to evaluate whether bone mineral density (BMD) ≥ −2.5 SD could be used as the treat-to-target (T2T) goal...
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Direct MR arthrography without image guidance: a practical guide, joint-by-joint
Direct MR arthrography (dMRA) is a fundamental technique in diagnosing pathology in major peripheral joints, allowing for precise evaluation of...
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Subclinical joint inflammation in rheumatoid arthritis: comparing thermal and ultrasound imaging at the metacarpophalangeal joint
BackgroundWhile ultrasound and MRI are both superior to clinical examination in the detection of joint inflammation, there is presently a lack of...
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Tibial intraneural ganglion cysts at the superior tibiofibular joint treated with joint resection alone: a proof of concept
BackgroundIntraneural ganglion cysts involving the tibial nerve are rare. Recent evidence has supported an articular (synovial) theory to explain the...
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A pathological joint–liver axis mediated by matrikine-activated CD4+ T cells
The knee joint has long been considered a closed system. The pathological effects of joint diseases on distant organs have not been investigated....
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Mechanistic target of rapamycin (mTOR): a potential new therapeutic target for rheumatoid arthritis
Rheumatoid arthritis (RA) is an autoimmune disease characterized by systemic synovitis and bone destruction. Proinflammatory cytokines activate...
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Relationship Between Cetuximab Target-Mediated Pharmacokinetics and Progression-Free Survival in Metastatic Colorectal Cancer Patients
Background and ObjectiveCetuximab, an anti-epidermal growth factor receptor (EGFR) monoclonal immunoglobulin (Ig)G1 antibody, has been approved for...
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Fibroblast expression of neurotransmitter receptor HTR2A associates with inflammation in rheumatoid arthritis joint
The study of neuroimmune crosstalk and the involvement of neurotransmitters in inflammation and bone health has illustrated their significance in...
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Bone marrow lesions in osteoarthritis: biomarker or treatment target? A narrative review
Osteoarthritis (OA) is a leading cause of pain, functional impairment, and disability in older adults. However, there are no effective treatments to...
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Imaging approach to prosthetic joint infection
The diagnosis of prosthetic joint infection (PJI) remains challenging, despite multiple available laboratory tests for both serum and synovial fluid...
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At the Crux of Joint Crosstalk: TGFβ Signaling in the Synovial Joint
Purpose of ReviewThe effect of the transforming growth factor beta (TGFβ) signaling pathway on joint homeostasis is tissue-specific, non-linear, and...
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Profiling joint tissues at single-cell resolution: advances and insights
Advances in the profiling of human joint tissues at single-cell resolution have provided unique insights into the organization and function of these...
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Is asymptomatic bacteriuria a noticeable risk factor for periprosthetic joint infection following total joint arthroplasty? A systematic review and meta-analysis
IntroductionTotal joint arthroplasty (TJA) is a common procedure that improves the quality of life for severe arthritis patients. The rising demand...
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Time course of changes in passive properties and joint position sense after static stretching
PurposeStatic stretching (SS) improves flexibility but may impair the accuracy of joint position sense. Therefore, this study aimed to investigate...
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Inflammatory diseases causing joint and bone destruction: rheumatoid arthritis and hemophilic arthropathy
Various diseases and conditions cause joint disorders. Osteoarthritis (OA) is characterized by the degeneration of articular cartilage, synovitis,...
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Joint manifestations revealing inborn metabolic diseases in adults: a narrative review
Inborn metabolic diseases (IMD) are rare conditions that can be diagnosed during adulthood. Patients with IMD may have joint symptoms and the...
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Critical distance of the sacroiliac joint for open reduction using screw fixation for traumatic sacroiliac joint diastasis: a retrospective study
BackgroundOsteosynthesis for sacroiliac joint (SIJ) diastasis using an iliosacral screw (ISS) and a trans-iliac-trans-sacral screw (TITSS) can be...
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Loss of β-arrestin2 aggravated condylar cartilage degeneration at the early stage of temporomandibular joint osteoarthritis
ObjectiveTemporomandibular joint osteoarthritis (TMJOA) is a chronic degenerative joint disorder characterized by extracellular matrix degeneration...