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Travel related histoplasmosis – a diagnostic challenge in a patient with tumor necrosis factor alpha (TNF-α) inhibitor therapy
IntroductionIn a non-endemic setting, disseminated histoplasmosis is a rare travel-related health problem of immunosuppressed returnees from endemic...
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Photobiomodulation effect in tumoral necrosis factor-alpha(TNF-α) on the viability of random skin flap in rats
The aim of this study was to investigate the effect of red laser (660 nm) photobiomodulation (PBM) with different energies on tumor necrosis...
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Polymorphisms of TNF-alpha (− 308), IL-1beta (+ 3954) and IL1-Ra (VNTR) are associated to severe stage of endometriosis in Mexican women: a case control study
BackgroundEndometriosis is an estrogen-dependent and chronic inflammatory disease affecting up to 10% of women. It is the result of a combined...
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Discontinuation and Switchback After Non-Medical Switching from Originator Tumor Necrosis Factor Alpha (TNF) Inhibitors to Biosimilars: A Meta-Analysis of Real-World Studies from 2012 to 2018
IntroductionTo examine the prevalence rates of biosimilar discontinuation and switchback to the originator tumor necrosis factor alpha (TNF)...
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TNF-alpha, IL-6, IL-10 and fatty acids in rheumatoid arthritis patients receiving cDMARD and bDMARD therapy
ObjectiveThe present study aimed to examine the effects of cDMARD and bDMARD therapy on both gene expressions and protein levels of TNF-α, IL-6,...
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Serum levels of soluble interleukin 2 receptor (sIL-2R), tumor necrosis factor-alpha (TNF-α), and immunoglobulin M are correlated with the disease extent in childhood Langerhans cell histiocytosis
PurposeThis study aimed to identify peripheral parameters associated with the severity of Langerhans cell histiocytosis (LCH) and to look for...
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Screening for latent tuberculosis before starting TNF-alpha inhibitors in a population with high BCG vaccination rates
It is assumed that in candidates for TNF-alpha inhibitor (TNFi) treatment, tuberculin skin test (TST) may be unreliable, since BCG vaccination causes...
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The effect of systemic levels of TNF-alpha and complement pathway activity on outcomes of VEGF inhibition in neovascular AMD
Background/ObjectivesSystemic levels of pro-inflammatory cytokines and activated complement components affect the risk and/or progression of...
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Genetic polymorphism of tumor necrosis factor alpha (TNF-α) and tumor necrosis factor beta (TNF-β) genes and risk of oral pre-cancer and cancer in North Indian population
ObjectiveThere are inconclusive data connecting single-nucleotide polymorphisms (SNPs) of TNF - α (rs361525) and TNF - β (rs909253) to potential...
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Effects of citral on serum inflammatory factors and liver gene expression of IL-6 and TNF-alpha in experimental diabetes
Citral is the main ingredient of the lemongrass plant with anti-inflammatory properties. In this study, the effects of citral on reducing...
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Evaluation of tumor necrosis factor-alpha (TNF-α); gamma interferon (IFN-γ) genes and oxidative stress in sheep: immunological responses induced by Oestrus ovis (Diptera: Oestridae) infestation
This study aimed to evaluate the cell mediated immune responses against Oestrus ovis ( O. ovis ) in sheep through measurement of the changes in mRNA...
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Efficacy of enteral nutrition in patients with Crohn’s disease on maintenance anti-TNF-alpha antibody therapy: a meta-analysis
Enteral nutrition (EN) is effective in Crohn’s disease (CD) patients and has been shown to have an inhibitory effect on loss of response to...
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Clinical manifestations and anti-TNF alpha therapy of juvenile Behçet’s disease in Taiwan
BackgroundsBehçet’s disease (BD) is a rare vasculitic disorder affecting all sizes of vessels. Among BD patients, 4 to 25% of patients with diagnosed...
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Role of Montelukast in modulation of response to sepsis in preterm infants: a randomized-controlled trial
BackgroundSince inflammatory mediators play a crucial role in the pathophysiology of neonatal sepsis. Montelukast, as an anti-inflammatory drug,...
