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Involvement of tissue changes induced by neoadjuvant treatment in total mesorectal excision (TME): novel suggestions for determining TME quality
BackgroundFew studies to date have investigated morphological changes after neoadjuvant treatment (NAT) and their implications in total mesorectal...
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Pan-cancer analysis of the TRAF family genes and their correlation with prognosis, TME, immune and drug sensitivity
BackgroundTumor necrosis factor receptor-associated factors family genes play a pivotal role in tumorigenesis and metastasis, functioning as adapters...
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Does the mesorectal fat area impact the histopathology metrics of the specimen in males undergoing TME for distal rectal cancer?
The aim of this study was to evaluate whether the mesorectal fat area (MFA) has an impact on the histopathology metrics of the specimen in male...
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Crosstalk among m6A RNA methylation, hypoxia and metabolic reprogramming in TME: from immunosuppressive microenvironment to clinical application
The tumor microenvironment (TME), which is regulated by intrinsic oncogenic mechanisms and epigenetic modifications, has become a research hotspot in...
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Outcomes of open vs laparoscopic vs robotic vs transanal total mesorectal excision (TME) for rectal cancer: a network meta-analysis
BackgroundTotal mesorectal excision (TME) for rectal cancer can be achieved using open (OpTME), laparoscopic (LapTME), robotic (RoTME), or transanal...
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Meta-analysis and Systematic Review in Patients with Locally Advanced Rectal Cancer with Total Mesorectal Excision (TME) Alone and TME Combined with Extended Pelvic Lymph Node Dissection After Neoadjuvant Chemoradiotherapy
AbstractLocally advanced rectal cancer with lateral pelvic lymph node metastasis connotates a poor prognosis. In the West, neoadjuvant...
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“Near-TME”: proposed standardisation of the technique for proctectomy in male patients with ulcerative colitis
BackgroundThe aim of the present study was to describe in detail an approach to proctectomy in ulcerative colitis (UC), which can be standardized;...
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Circ_16601 facilitates Hippo pathway signaling via the miR-5580-5p/FGB axis to promote my-CAF recruitment in the TME and LUAD progression
BackgroundLung cancer represents a significant public health issue in China, given its high incidence and mortality rates. Circular RNAs (circRNAs)...
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Long-term oncologic outcomes of transanal TME compared with transabdominal TME for rectal cancer: a systematic review and meta-analysis
BackgroundTransanal total mesorectal excision (TaTME) appears to have favorable surgical and pathological outcomes. However, the evidence on survival...
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Early experience with the ARTISENTIAL® articulated instruments in laparoscopic low anterior resection with TME
BackgroundThe notion of articulation in surgery has been largely synonymous with robotics. The ARTISENTIAL ® instruments aim at bringing advanced...
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Surgical coaching applied to laparoscopic TME for continuous professional development in rectal surgery: proof of concept
BackgroundCoaching is maturing as a strategy for surgeons’ continuous professional development in different types of surgery. Laparoscopic total...
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Extended Total Mesorectal Excision (e-TME) for Locally Advanced Rectal Cancer
BackgroundLocally advanced rectal cancer (LARC) can involve surrounding pelvic organs requiring multivisceral resection. Extended total mesorectal...
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Completion surgery vs. primary TME for early rectal cancer: a national study
PurposeWhile local excision by transanal endoscopic microsurgery (TEM) or transanal minimally invasive surgery (TAMIS) is an option for low-risk...
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Construction of TME and Identification of crosstalk between malignant cells and macrophages by SPP1 in hepatocellular carcinoma
Liver cancer accounts for 6% of all malignancies causing death worldwide, and hepatocellular carcinoma (HCC) is the most common histological type....