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Proteomic aptamer analysis reveals serum markers that characterize preclinical systemic sclerosis (SSc) patients at risk for progression toward definite SSc
BackgroundThe study of molecular mechanisms characterizing disease progression may be relevant to get insights into systemic sclerosis (SSc)...
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Assessing dyspnea-related kinesiophobia in patients with systemic sclerosis (SSc): validity and reliability of Turkish Breathlessness Beliefs Questionnaire for SSc
Introduction/objectiveThe respiratory system is often affected by systemic sclerosis (SSc), a connective tissue disease characterized by fibrosis,...
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Biomarkers in Systemic Sclerosis Associated Interstitial Lung Disease (SSc-ILD)
Purpose of ReviewInterstitial lung disease (ILD) is the leading cause of mortality in systemic sclerosis, a rare autoimmune disease characterised by...
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Sirtuin3 and Sirtuin7 are promising biomarkers in systemic sclerosis
BackgroundSystemic sclerosis (SSc) is an autoimmune disease that results in micro-vasculopathy, leading to organ dysfunction. Sirtuins are known for...
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Diagnosis of interstitial lung disease (ILD) secondary to systemic sclerosis (SSc) and rheumatoid arthritis (RA) and identification of ‘progressive pulmonary fibrosis’ using chest CT: a narrative review
Interstitial lung disease (ILD) is a frequent manifestation of connective tissue diseases (CTDs), with incidence and prevalence variously assessed in...
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Recent Advances in Treatment of Systemic Sclerosis and Morphea
Systemic sclerosis (SSc) and morphea are autoimmune sclerosing diseases that cause significant morbidity, and in the case of SSc, mortality. The...
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Managing Symptoms of Systemic Sclerosis for the Allergist-Immunologist
Purpose of ReviewSystemic sclerosis (SSc) is a chronic, multisystem, autoimmune disease characterized by fibrosis, vasculopathy and immune system...
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Respiratory failure in systemic sclerosis
Systemic sclerosis (SSc) can lead to dyspnea and respiratory failure through multiple mechanisms, making a precise diagnosis particularly...
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Late-age onset systemic sclerosis—clinical and serological characteristics
The clinical course and serological profile of the late-age onset systemic sclerosis (LAO SSc) and the early-age onset SSc (EAO SSc) was compared....
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Macular choroidal thickness, volume, and vascularity index in patients with systemic sclerosis
PurposeThe aim of this study was to investigate choroidal parameters in patients with systemic sclerosis (SSc) using enhanced depth imaging...
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Serum markers in systemic sclerosis with cardiac involvement
Cardiac involvement in systemic sclerosis is a common clinical entity that may range from subclinical to life-threatening complications. The...
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A Rare Case of Renal Crisis in Systemic Sclerosis–Systemic Lupus Eritematosus Overlap Syndrome: A Case Report and Literature Review
We present a patient with systemic sclerosis–systemic lupus eritematosus (SSc-SLE) overlap syndrome who was initially diagnosed as SLE. The patient...
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Clinical characteristics of systemic sclerosis patients with occupational silicosis
To explore the clinical characteristics of systemic sclerosis complicated with silicosis. The systemic sclerosis patients treated in the Guangxi...
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Systemic sclerosis interstitial lung disease: unmet needs and potential solutions
Systemic sclerosis (SSc), or scleroderma, is a rare, complex, systemic autoimmune disease of unknown aetiology, characterized by high morbidity and...
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Proteomic biomarkers for survival in systemic sclerosis-associated pulmonary hypertension
BackgroundInterstitial lung disease (ILD) and pulmonary hypertension (PH) represent the major causes of mortality in systemic sclerosis (SSc)....
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Treatable Traits in Systemic Sclerosis
Systemic sclerosis (SSc) is a chronic systemic disease within the spectrum of connective tissue diseases, specifically characterized by vascular...
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Systemic sclerosis associated respiratory involvement: Scopus-based analysis of articles in 2013–2022
BackgroundSystemic sclerosis (SSc), a complex autoimmune disorder, manifests as a convergence of rheumatologic, dermatologic, and pulmonary...
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Significance of serum Krebs von den Lungen-6 in systemic sclerosis
BackgroundSystemic sclerosis (SSc) is a well-known multi-system connective tissue disease, it has an unidentified aetiology that is characterised by...
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Myopericarditis revealing a systemic sclerosis-systemic lupus erythematosus overlap syndrome complicated by fatal cytomegalovirus infection: a case report
BackgroundSystemic sclerosis (SSc)-systemic lupus erythematosus (SLE) overlap syndrome is rarely described in the literature, and its morbidity and...
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Systemic Sclerosis-Associated Myopathy: How to Treat
Purpose of ReviewSystemic sclerosis (SSc) and myositis are two different entities that may coexist as an overlap syndrome. Immunological biomarkers...
