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Synthetic cannabinoids impact on cognitive functions
BackgroundSynthetic cannabinoids SC are now becoming progressively popular among young people worldwide; little is known about their negative...
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Radiological findings in poisoning by synthetic cannabinoids adulterated with brodifacoum
ObjectivesSevere coagulopathy due to consumption of synthetic cannabinoids adulterated with brodifacoum, a long-acting anticoagulant, is an emerging...
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Death after smoking of fentanyl, 5F-ADB, 5F-MDMB-P7AICA and other synthetic cannabinoids with a bucket bong
PurposeWe report a case of a polydrug user who consumed various synthetic cannabinoids and fentanyl from a transdermal patch via a bucket bong....
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The synthetic cannabinoids menace: a review of health risks and toxicity
Synthetic cannabinoids (SCs) are chemically classified as psychoactive substances that target the endocannabinoid system in many body organs. SCs can...
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Synthetic Cannabinoids and Cannabis: How the Patterns of Use Differ: Results from the European Web Survey on Drugs
The aim of the current study is to assess if the patterns of use, socio-demographic characteristics, and use of other drugs differ among people who...
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Clinical pattern of synthetic cannabinoids users in Upper Egypt: cross-sectional study
BackgroundThere is an expanding use of new psychoactive substances containing synthetic cannabinoids in the last years. This study was conducted to...
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Cannabinoids for Acute Pain Management: Approaches and Rationale
Purpose of the ReviewAcute pain management remains a challenge and postoperative pain is often undermanaged despite many available treatment options,...
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Fatal intoxication with new synthetic cannabinoids 5F-MDMB-PICA and 4F-MDMB-BINACA—parent compounds and metabolite identification in blood, urine and cerebrospinal fluid
Synthetic cannabinoids (SCs) remain one of the largest groups of new psychoactive substances. Recently, new synthetic cannabinoids 5F-MDMB-PICA and...
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Cytotoxicity associated with acute and chronic administration of synthetic cannabinoids “Strox” in the brain, liver, heart, and testes of male albino rats: histological and immunohistochemical study
BackgroundSynthetic cannabinoids are one of the largest groups of new psychoactive substances that invaded Egypt’s drug abuse market over the past...
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Cannabinoids in Symptomatic Treatment for People with Multiple Sclerosis: a Systematic Review of Randomised Studies
Purpose of ReviewThe use of cannabinoid-based medicines in symptomatic treatment for people with multiple sclerosis (MS) is high. This review aimed...
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Review: Cannabinoids as Medicinals
Purpose of reviewThere have been many debates, discussions, and published writings about the therapeutic value of cannabis plant and the hundreds of...
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Phase I-metabolism studies of the synthetic cannabinoids PX-1 and PX-2 using three different in vitro models
PurposeSynthetic cannabinoids (SCs), highly metabolized substances, are rarely found unmodified in urine samples. Urine screening relies on SC...
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Examining the role of cannabinoids on osteoporosis: a review
PurposePrior research studies have shown that the endocannabinoid system, influenced by CBD and THC, plays a role in bone remodeling. As both the...
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Cannabinoids as a Potential Alternative to Opioids in the Management of Various Pain Subtypes: Benefits, Limitations, and Risks
IntroductionPain is a global phenomenon encompassing many subtypes that include neuropathic, musculoskeletal, acute postoperative, cancer, and...
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Gastrointestinal manifestations of synthetic cannabinoids: a retrospective cohort study
BackgroundSynthetic cannabinoids (SC) are chemical substances which activate cannabinoid receptors similarly to tetrahydrocannabinol, but with a...
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Semi-quantitative analysis of cannabinoids in hemp (Cannabis sativa L.) using gas chromatography coupled to mass spectrometry
BackgroundHemp ( Cannabis sativa L.) is a producer of cannabinoids. These organic compounds are of increasing interest due to their potential...
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Medical cannabinoids: a pharmacology-based systematic review and meta-analysis for all relevant medical indications
BackgroundMedical cannabinoids differ in their pharmacology and may have different treatment effects. We aimed to conduct a pharmacology-based...
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Cannabinoids in the management of behavioral, psychological, and motor symptoms of neurocognitive disorders: a mixed studies systematic review
AimWe undertook this systematic review to determine the efficacy and safety of cannabis-based medicine as a treatment for behavioral, psychological,...
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Cannabinoids in the landscape of cancer
IntroductionCannabinoids are a group of terpenophenolic compounds derived from the Cannabis sativa L. plant. There is a growing body of evidence...
